Abstract: A method and system for mitigating a threat associated with network data packets are provided. The method commences with receiving, by an authentication server, a request for access to a server from a client. The method further includes authenticating the client by the authentication server. The authentication includes providing an authentication token to the client. The method continues with receiving, by a mitigation device, from the client, at least one network packet directed to the server. The at least one network packet embeds the authentication token. The method further includes validating, by the mitigation device, authenticity of the authentication token and selectively forwarding, based on the validation, the at least one network packet to the server. The authentication token is independently generated by the authentication server, the mitigation device, and the server using a shared token generation algorithm based on a hash salt value.

Abstract: A method and system for mitigating a threat associated with network data packets are provided. The method commences with receiving, by an authentication server, a request for access to a server from a client. The method further includes authenticating the client by the authentication server. The authentication includes providing an authentication token to the client. The method continues with receiving, by a mitigation device, from the client, at least one network packet directed to the server. The at least one network packet embeds the authentication token. The method further includes validating, by the mitigation device, authenticity of the authentication token and selectively forwarding, based on the validation, the at least one network packet to the server. The authentication token is independently generated by the authentication server, the mitigation device, and the server using a shared token generation algorithm based on a hash salt value.

Abstract: A method and system for mitigating a threat associated with network data packets are provided. The method commences with receiving, by an authentication server, a request for access to a server from a client. The method further includes authenticating the client by the authentication server. The authentication includes providing an authentication token to the client. The method continues with receiving, by a mitigation device, from the client, at least one network packet directed to the server. The at least one network packet embeds the authentication token. The method further includes validating, by the mitigation device, authenticity of the authentication token and selectively forwarding, based on the validation, the at least one network packet to the server. The authentication token is independently generated by the authentication server, the mitigation device, and the server using a shared token generation algorithm based on a hash salt value.

Abstract: The invention relates to antigen-binding molecules that specifically binds ALPPL2 and/or ALPP but not ALPL or ALPI. It also relates to a pharmaceutical composition, an immunoconjugate and a chimeric antigen receptor comprising said antigen-binding molecules. The invention also relates to methods for reducing the expression or activity of ALPPL2 in a cancer cell and methods of treating a cancer in a subject.

Abstract: A method and system for mitigating a threat associated with network data packets are provided. The method commences with receiving, by an authentication server, a request for access to a server from a client. The method further includes authenticating the client by the authentication server. The authentication includes providing an authentication token to the client. The method continues with receiving, by a mitigation device, from the client, at least one network packet directed to the server. The at least one network packet embeds the authentication token. The method further includes validating, by the mitigation device, authenticity of the authentication token and selectively forwarding, based on the validation, the at least one network packet to the server. The authentication token is independently generated by the authentication server, the mitigation device, and the server using a shared token generation algorithm based on a hash salt value.

Abstract: We describe an antibody or antigen-binding fragment thereof comprising a heavy chain variable region (VH) sequence and a light chain variable region (VL) sequence of a clone selected from: 5C4, 4H1, 1D2, 1C4, 2B5, 1F1, 1H1, 4A5, 1D8, 1D3, 2F1, 3C6, 3D12, 3A9, 1F4, 1H10, 3C12, 4G11, 4A12, 1A12, 3G12, 4F9, 4G4 and 1E1 which is capable of specifically binding to glypican-3 (GPC-3) (GenBank Accession Number: NP_004475.1), or a sequence having at least 75%, 80%, 85%, 90%, 95%, 96%, 97%, 98% or 99% sequence identity thereto.

Abstract: Antibodies and fragments thereof which bind to peptide-MHC complexes are described. In particular, an antibody binding to a peptide-MHC complex comprising a peptide of p53 and a MHC Class I molecule comprising ?-chain encoded by an HLA-A*24 allele is claimed. Also disclosed are compositions comprising such antibodies and fragments, and uses and methods of treating, preventing and diagnosing cancers using the same.

Abstract: An active output compensation circuit is adopted for use on a power supply which receives input power and regulates to become a plurality of different output power. The power supply has a transformer to transform the input power. The transformer has a secondary side connecting to a plurality of output regulation units to deliver the output power. The active output compensation circuit includes a voltage difference judgment unit electrically connected to the output regulation units and a plurality of compensation channel switches. The compensation channel switches bridge two output regulation units and the voltage difference judgment unit. The voltage difference judgment unit judges the voltage difference of two output power and determines whether to output an ON signal. The compensation channel switches are driven by the ON signal and set ON so that one output power can compensate another output power.

Abstract: An active output compensation circuit is adopted for use on a power supply which receives input power and regulates to become a plurality of different output power. The power supply has a transformer to transform the input power. The transformer has a secondary side connecting to a plurality of output regulation units to deliver the output power. The active output compensation circuit includes a voltage difference judgment unit electrically connected to the output regulation units and a plurality of compensation channel switches. The compensation channel switches bridge two output regulation units and the voltage difference judgment unit. The voltage difference judgment unit judges the voltage difference of two output power and determines whether to output an ON signal. The compensation channel switches are driven by the ON signal and set ON so that one output power can compensate another output power.

Abstract: The invention is an assay for detection of Watermelon silver mottle virus (WSMoV)-serogroup tospoviruses using a monoclonal antibody and a method for preparing the monoclonal antibody. A hybridoma cell line that produces a monoclonal antibody against the NSs proteins of WSMoV-serogroup tospoviruses was produced. The hybridoma cell line produces a monoclonal antibody binding with peptide SEQ ID No. 19.

Abstract: A transforming circuit for power supplier includes a primary winding coil; a secondary winding coil and a secondary rectifier circuit, an AC power being transformed by the secondary winding coil in accordance with a winding turns ratio relative to the primary winding coil and converted by the secondary rectifier circuit into a first-potential DC power; N+1 sets of potential modifying circuits, connected in parallel with the first-potential DC power, each set of potential modifying circuits being based on the first-potential DC power and transformed thereof into N+1 sets of second-potential DC power at differential potential, N?1. Thereby, DC power at different potentials can be provides so that the power output can be more flexible and effective.

Abstract: A transformer having a leakage inductance control structure includes a primary coil, a secondary coil formed at a selected coil ratio relative to the primary coil to transform voltage and output electric power, and a leakage inductance control coil which is wound on the secondary coil in an insulation manner according to a selected coupling efficiency and electrically connected to the primary coil. Through electromagnetic coupling of the leakage inductance control coil and the secondary coil a power control signal is output and sent to the primary coil to control leakage inductance of the primary coil.

Abstract: A multiple safety monitoring system comprises a weight meter in a first control section; a door of a control section having a card reader for identifying a card for determining a person; the weight meter serving for measuring a weight of a person; the value of measured weight being transferred and stored in a central control system of a computer through a protocol converter and a hub for contrasting and determining whether the weight is within a permissible range; in the first control section, each time, only a person is permitted to enter into the door of the first control section; monitors arranged in the second and third control section for determining movement of persons in the control sections; the monitors having monitor recording systems which are connected to a programmable logic device electrically; and signals being transferred to the programmable logic device for processing.