Patents by Inventor Ching-Yue Lai

Ching-Yue Lai has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Publication number: 20240010949
    Abstract: Provided among other things is a cleaning composition comprising: a carrier fluid; and Minute Fibrils suspended in the carrier fluid, wherein the composition is protein cleaning effective.
    Type: Application
    Filed: May 2, 2023
    Publication date: January 11, 2024
    Inventors: Mohamed Emam Labib, Stanislav S. Dukhin, Yacoob Tabani, Ching-Yue Lai, James L. Manganaro, Peter Materna, Jeffrey C. Robertson
  • Patent number: 11680226
    Abstract: Provided among other things is a cleaning composition comprising: a carrier fluid; and Minute Fibrils suspended in the carrier fluid, wherein the composition is protein cleaning effective.
    Type: Grant
    Filed: May 5, 2022
    Date of Patent: June 20, 2023
    Assignee: Novaflux, Inc..
    Inventors: Mohamed Emam Labib, Stanislav S. Dukhin, Yacoob Tabani, Ching-Yue Lai, James L. Manganaro, Peter Materna, Jeffrey C. Robertson
  • Publication number: 20220396752
    Abstract: Provided among other things are a cleaning composition comprising a carrier fluid comprising in the carrier fluid polymer comprising particulate super absorbent polymer (PSAP), wherein the PSAP as in the cleaning composition is substantially at the percolation volume fraction or higher; wherein the cleaning composition can be passed over a surface driven by a pressure drop effective to render the composition traditional biofilm (TBF) cleaning effective and protein cleaning effective.
    Type: Application
    Filed: May 23, 2022
    Publication date: December 15, 2022
    Inventors: Mohamed Emam Labib, Stanislav S. Dukhin, Yacoob Tabani, Ching-Yue Lai, James L. Manganaro, Peter Materna, Jeffrey C. Robertson, Seo Yean Sohn
  • Publication number: 20220267698
    Abstract: Provided among other things is a cleaning composition comprising: a carrier fluid; and Minute Fibrils suspended in the carrier fluid, wherein the composition is protein cleaning effective.
    Type: Application
    Filed: May 5, 2022
    Publication date: August 25, 2022
    Inventors: Mohamed Emam Labib, Stanislav S. Dukhin, Yacoob Tabani, Ching-Yue Lai, James L. Manganaro, Peter Materna, Jeffrey C. Robertson
  • Patent number: 11345878
    Abstract: Provided among other things are a cleaning composition comprising a carrier fluid comprising in the carrier fluid polymer comprising particulate super absorbent polymer (PSAP), wherein the PSAP as in the cleaning composition is substantially at the percolation volume fraction or higher; wherein the cleaning composition can be passed over a surface driven by a pressure drop effective to render the composition traditional biofilm (TBF) cleaning effective and protein cleaning effective.
    Type: Grant
    Filed: April 3, 2019
    Date of Patent: May 31, 2022
    Assignee: Novaflux Inc.
    Inventors: Mohamed Emam Labib, Stanislav S. Dukhin, Yacoob Tabani, Ching-Yue Lai, James L. Manganaro, Peter Materna, Jeffrey C. Robertson, Seo Yean Sohn
  • Patent number: 11326128
    Abstract: Provided among other things is a cleaning composition comprising: a carrier fluid; and Minute Fibrils suspended in the carrier fluid, wherein the composition is protein cleaning effective.
    Type: Grant
    Filed: February 19, 2019
    Date of Patent: May 10, 2022
    Assignee: Novaflux, Inc.
    Inventors: Mohamed Emam Labib, Stanislav S. Dukhin, Yacoob Tabani, Ching-Yue Lai, James L. Manganaro, Peter Materna, Jeffrey C. Robertson
  • Publication number: 20220008335
    Abstract: Hollow fiber drug delivery devices are described. Device can contain structural or solid fibers. Fabric can be formed by fibers being interwoven or joined to each other. All or some of the fibers can be resorbable. Fibers can be subdivided, by deformations or closure points, into numerous compartments that separately deliver drug. Deformations can be located at points of fiber intersection or joining. Different drug or drug formulation can be provided in different places. Fibers can be given appropriate surface treatments or coatings to achieve desired properties such as wetting of pores and surfaces. Different release characteristics in different directions can be achieved. The hollow fibers can contain solid particles of drug, and can contain gel. Possible applications include hernia meshes, pouches, sutures, catheters, wound dressings, stents, nerve regrowth guides, refillable/drainable devices, and devices that deliver drug to lymphatic flow.
    Type: Application
    Filed: March 18, 2021
    Publication date: January 13, 2022
    Inventors: Mohamed E. Labib, Stanislav S, Dukhin, Peter Materna, Jeffrey C. Robertson, Ching-Yue Lai, Yacoob Tabani
  • Patent number: 11191613
    Abstract: Provided among other things is a sampling system for determining an amount or type of contamination a narrow, elongated passageway in a medical device, said sampling system comprising: (a) a fluid supply system that supplies to said passageway a sampling liquid for flowing through said passageway and a gas for flowing through said passageway; and (b) a receiving container that receives liquid from said passageway, wherein said sampling liquid is sterile, wherein said sampling liquid is configured to allow recovery of viable pathogens from the passageway, and wherein said sampling liquid comprises an amount and selection of surfactant effective to enhance the dislodgement of Enterococcus faecalis and Pseudomonas aeruginosa bacteria from the narrow passageways.
    Type: Grant
    Filed: August 29, 2019
    Date of Patent: December 7, 2021
    Assignee: Novaflux, Inc.
    Inventors: Mohamed E. Labib, Stanislav S. Dukhin, Jeffrey C. Robertson, Peter Materna, Ching-Yue Lai, Yacoob Tabani
  • Patent number: 10952961
    Abstract: Hollow fiber drug delivery devices are described. Device can contain structural or solid fibers. Fabric can be formed by fibers being interwoven or joined to each other. All or some of the fibers can be resorbable. Fibers can be subdivided, by deformations or closure points, into numerous compartments that separately deliver drug. Deformations can be located at points of fiber intersection or joining. Different drug or drug formulation can be provided in different places. Fibers can be given appropriate surface treatments or coatings to achieve desired properties such as wetting of pores and surfaces. Different release characteristics in different directions can be achieved. The hollow fibers can contain solid particles of drug, and can contain gel. Possible applications include hernia meshes, pouches, sutures, catheters, wound dressings, stents, nerve regrowth guides, refillable/drainable devices, and devices that deliver drug to lymphatic flow.
    Type: Grant
    Filed: December 12, 2019
    Date of Patent: March 23, 2021
    Assignee: Novaflux, Inc.
    Inventors: Mohamed E. Labib, Stanislav S. Dukhin, Peter Materna, Jeffrey C. Robertson, Ching-Yue Lai, Yacoob Tabani
  • Publication number: 20200270551
    Abstract: Provided among other things are a cleaning composition comprising a carrier fluid comprising in the carrier fluid polymer comprising particulate super absorbent polymer (PSAP), wherein the PSAP as in the cleaning composition is substantially at the percolation volume fraction or higher; wherein the cleaning composition can be passed over a surface driven by a pressure drop effective to render the composition traditional biofilm (TBF) cleaning effective and protein cleaning effective.
    Type: Application
    Filed: April 3, 2019
    Publication date: August 27, 2020
    Inventors: Mohamed Emam LABIB, Stanislav S. DUKHIN, Yacoob TABANI, Ching-Yue LAI, James L. MANGANARO, Peter MATERNA, Jeffrey C. ROBERTSON, Seo Yean SOHN
  • Publication number: 20200138708
    Abstract: Hollow fiber drug delivery devices are described. Device can contain structural or solid fibers. Fabric can be formed by fibers being interwoven or joined to each other. All or some of the fibers can be resorbable. Fibers can be subdivided, by deformations or closure points, into numerous compartments that separately deliver drug. Deformations can be located at points of fiber intersection or joining. Different drug or drug formulation can be provided in different places. Fibers can be given appropriate surface treatments or coatings to achieve desired properties such as wetting of pores and surfaces. Different release characteristics in different directions can be achieved. The hollow fibers can contain solid particles of drug, and can contain gel. Possible applications include hernia meshes, pouches, sutures, catheters, wound dressings, stents, nerve regrowth guides, refillable/drainable devices, and devices that deliver drug to lymphatic flow.
    Type: Application
    Filed: December 12, 2019
    Publication date: May 7, 2020
    Inventors: Mohamed E. LABIB, Stanislav S. DUKHIN, Peter MATERNA, Jeffrey C. ROBERTSON, Ching-Yue LAI, Yacoob TABANI
  • Publication number: 20200054415
    Abstract: Provided among other things is a sampling system for determining an amount or type of contamination a narrow, elongated passageway in a medical device, said sampling system comprising: (a) a fluid supply system that supplies to said passageway a sampling liquid for flowing through said passageway and a gas for flowing through said passageway; and (b) a receiving container that receives liquid from said passageway, wherein said sampling liquid is sterile, wherein said sampling liquid is configured to allow recovery of viable pathogens from the passageway, and wherein said sampling liquid comprises an amount and selection of surfactant effective to enhance the dislodgement of Enterococcus faecalis and Pseudomonas aeruginosa bacteria from the narrow passageways.
    Type: Application
    Filed: August 29, 2019
    Publication date: February 20, 2020
    Inventors: Mohamed E. Labib, Stanislav S. Dukhin, Jeffrey C. Robertson, Peter Materna, Ching-Yue Lai, Yacoob Tabani
  • Patent number: 10512523
    Abstract: Provided among other things is a sampling system for determining an amount or type of contamination a narrow, elongated passageway in a medical device, said sampling system comprising: (a) a fluid supply system that supplies to said passageway a sampling liquid for flowing through said passageway and a gas for flowing through said passageway; and (b) a receiving container that receives liquid from said passageway, wherein said sampling liquid is sterile, wherein said sampling liquid is configured to allow recovery of viable pathogens from the passageway, and wherein said sampling liquid comprises an amount and selection of surfactant effective to enhance the dislodgement of Enterococcus faecalis and Pseudomonas aeruginosa bacteria from the narrow passageways.
    Type: Grant
    Filed: August 24, 2017
    Date of Patent: December 24, 2019
    Assignee: Novaflux, Inc.
    Inventors: Mohamed E. Labib, Stanislav S. Dukhin, Jeffrey C. Robertson, Peter Materna, Ching-Yue Lai, Yacoob Tabani
  • Publication number: 20190249115
    Abstract: Provided among other things is a cleaning composition comprising: a carrier fluid; and Minute Fibrils suspended in the carrier fluid, wherein the composition is protein cleaning effective.
    Type: Application
    Filed: February 19, 2019
    Publication date: August 15, 2019
    Inventors: Mohamed Emam Labib, Stanislav S. Dukhin, Yacoob Tabani, Ching-Yue Lai, James L. Manganaro, Peter Materna, Jeffrey C. Robertson
  • Patent number: 10266793
    Abstract: Provided among other things is a cleaning composition comprising: a carrier fluid; and Minute Fibrils suspended in the carrier fluid, wherein the composition is protein cleaning effective.
    Type: Grant
    Filed: September 28, 2017
    Date of Patent: April 23, 2019
    Assignee: Novaflux, Inc.
    Inventors: Mohamed Emam Labib, Stanislav S. Dukhin, Yacoob Tabani, Ching-Yue Lai, James L. Manganaro, Peter Materna, Jeffrey C. Robertson
  • Publication number: 20180200185
    Abstract: Hollow fiber drug delivery devices are described. Device can contain structural or solid fibers. Fabric can be formed by fibers being interwoven or joined to each other. All or some of the fibers can be resorbable. Fibers can be subdivided, by deformations or closure points, into numerous compartments that separately deliver drug. Deformations can be located at points of fiber intersection or joining. Different drug or drug formulation can be provided in different places. Fibers can be given appropriate surface treatments or coatings to achieve desired properties such as wetting of pores and surfaces. Different release characteristics in different directions can be achieved. The hollow fibers can contain solid particles of drug, and can contain gel. Possible applications include hernia meshes, pouches, sutures, catheters, wound dressings, stents, nerve regrowth guides, refillable/drainable devices, and devices that deliver drug to lymphatic flow.
    Type: Application
    Filed: July 22, 2016
    Publication date: July 19, 2018
    Inventors: Mohamed E. LABIB, Stanislav S. DUKHIN, Peter MATERNA, Jeffrey C. ROBERTSON, Ching-Yue LAI, Yacoob TABANI
  • Publication number: 20180125606
    Abstract: Provided among other things is a sampling system for determining an amount or type of contamination a narrow, elongated passageway in a medical device, said sampling system comprising: (a) a fluid supply system that supplies to said passageway a sampling liquid for flowing through said passageway and a gas for flowing through said passageway; and (b) a receiving container that receives liquid from said passageway, wherein said sampling liquid is sterile, wherein said sampling liquid is configured to allow recovery of viable pathogens from the passageway, and wherein said sampling liquid comprises an amount and selection of surfactant effective to enhance the dislodgement of Enterococcus faecalis and Pseudomonas aeruginosa bacteria from the narrow passageways.
    Type: Application
    Filed: August 24, 2017
    Publication date: May 10, 2018
    Inventors: Mohamed E. Labib, Stanislav S. Dukhin, Jeffrey C. Robertson, Peter Materna, Ching-Yue Lai, Yacoob Tabani
  • Publication number: 20180094214
    Abstract: Provided among other things is a cleaning composition comprising: a carrier fluid; and Minute Fibrils suspended in the carrier fluid, wherein the composition is protein cleaning effective.
    Type: Application
    Filed: September 28, 2017
    Publication date: April 5, 2018
    Inventors: Mohamed Emam Labib, Stanislav S. Dukhin, Yacoob Tabani, Ching-Yue Lai, James L. Manganaro, Peter Materna, Jeffrey C. Robertson
  • Patent number: 9492853
    Abstract: A method for cleaning an internal surface of a narrow diameter channel includes steps of: flowing a liquid cleaning medium and a gas through the narrow diameter channel under a flow regime that creates surface flow entities in contact with and sliding along the internal surface of the narrow diameter channel, the surface flow entities having three-phase contact lines and associated menisci, the surface flow entities detaching contaminants with which they come in contact from the internal surface of the narrow diameter internal surface of the narrow diameter channel; and rinsing the internal surface of the narrow diameter channel to remove residual liquid cleaning medium and detached contaminants from the channel.
    Type: Grant
    Filed: February 13, 2012
    Date of Patent: November 15, 2016
    Assignee: Olympus Corporation
    Inventors: Mohamed Emam Labib, Stanislav S. Dukhin, Joseph J. Murawski, Yacoob Tabani, Ching-Yue Lai
  • Publication number: 20150096598
    Abstract: Apparatus and methods are disclosed for cleaning interiors of passageways in endoscopes or other luminal medical devices by flow of liquid and gas therethrough. The liquid flow may include rivulets, droplets or other liquid entities which move on the internal surfaces of the passageways, and may include a three-phase contact interface between liquid and dry solid and gas.
    Type: Application
    Filed: June 9, 2014
    Publication date: April 9, 2015
    Inventors: Mohamed Eman Labib, Ching-Yue Lai, Yacoob Tabani, Ziye Qian, Stanislav S. Dukhin, Joseph J. Murawski