Patents by Inventor Chintan PAREKH

Chintan PAREKH has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • BCL11B Overexpression to Enhance Human Thymopoiesis and T Cell Function
    Publication number: 20220347222
    Abstract: Methods of treating a subject using a T cell therapy are disclosed herein. The methods include increasing BCL11B expression in hematopoietic stem and progenitor cells (HSPCs), pluripotent stem cells, or mature T cells to form modified cells and administering a therapeutically effective amount of the modified cells to the subject for the T cell therapy. BCL11B expression in the HSPCs, pluripotent stem cells, or mature T cells increases production and/or proliferation of T cells from the HSPCs and/or the pluripotent stem cells, and/or increases proliferation of the T cells.
    Type: Application
    Filed: June 24, 2020
    Publication date: November 3, 2022
    Applicants: The Regents of the University of California, Children's Hospital Los Angeles
    Inventors: Chintan PAREKH, Gay CROOKS, Christopher SEETS, Amelie Montel-Hagen