Patents by Inventor Chio Mui Chan

Chio Mui Chan has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • LOW-VISCOSITY, HIGH CONCENTRATION EVOLOCUMAB FORMULATIONS AND METHODS OF MAKING THE SAME
    Publication number: 20230226177
    Abstract: Provided herein are formulations of PCSK9-binding polypeptides, such as those comprising evolocumab, that comprise N-acetyl arginine and have reduced viscosities when compared to formulations lacking N-acetyl arginine. Provided herein are also methods of formulating such compositions that are advantageous in that they conserve certain components. Such formulations comprising PCSK9-binding polypeptides can be administered to patients to treat and/or prevent PCSK9-related diseases, conditions, and disorders.
    Type: Application
    Filed: August 23, 2022
    Publication date: July 20, 2023
    Inventors: Christopher James SLOEY, Sekhar KANAPURAM, Huanchun CUI, Chio Mui CHAN, Elaheh BINABAJI
  • Method of Antigen-Binding Protein Production
    Publication number: 20230069095
    Abstract: The present disclosure relates to methods of re-oxidizing an antigen-binding protein.
    Type: Application
    Filed: August 24, 2022
    Publication date: March 2, 2023
    Inventors: Elaheh Binabaji, Chio Mui Chan, Hadley Krizner, Junfen Ma, Diana Woehle
  • Low-viscosity, high concentration evolocumab formulations and methods of making the same
    Patent number: 11464857
    Abstract: Provided herein are formulations of PCSK9-binding polypeptides, such as those comprising evolocumab, that comprise N-acetyl arginine and have reduced viscosities when compared to formulations lacking N-acetyl arginine. Provided herein are also methods of formulating such compositions that are advantageous in that they conserve certain components. Such formulations comprising PCSK9-binding polypeptides can be administered to patients to treat and/or prevent PCSK9-related diseases, conditions, and disorders.
    Type: Grant
    Filed: February 22, 2018
    Date of Patent: October 11, 2022
    Assignee: AMGEN INC.
    Inventors: Christopher James Sloey, Sekhar Kanapuram, Huanchun Cui, Chio Mui Chan, Elaheh Binabaji
  • Method of antigen-binding protein production
    Patent number: 11447547
    Abstract: The present disclosure relates to methods of re-oxidizing an antigen-binding protein.
    Type: Grant
    Filed: December 13, 2018
    Date of Patent: September 20, 2022
    Assignee: AMGEN INC.
    Inventors: Elaheh Binabaji, Chio Mui Chan, Hadley Krizner, Junfen Ma, Diana Woehle
  • ANTIGEN BINDING CONSTRUCTS TO TARGET MOLECULES
    Publication number: 20220089730
    Abstract: Antigen binding constructs that bind to desired targets are disclosed, for example antibodies, including antibody fragments (such as scFv and minibodies) that bind to a target molecule, and have one or more of the disclosed hinges are described herein. Methods of use are described herein.
    Type: Application
    Filed: November 15, 2021
    Publication date: March 24, 2022
    Inventors: Chio Mui Chan, Jean Marie Gudas, Tove Olafsen, Daulet Kadyl Satpayev, Michael Yuri Torgov
  • Antigen binding constructs to target molecules
    Patent number: 11254744
    Abstract: Antigen binding constructs that bind to desired targets are disclosed, for example antibodies, including antibody fragments (such as scFv and minibodies) that bind to a target molecule, and have one or more of the disclosed hinges are described herein. Methods of use are described herein.
    Type: Grant
    Filed: August 4, 2016
    Date of Patent: February 22, 2022
    Assignee: IMAGINAB, INC.
    Inventors: Chio Mui Chan, Jean Gudas, Tove Olafsen, Daulet Kadyl Satpayev, Michael Yuri Torgov
  • Antigen binding constructs to target molecules
    Patent number: 11203639
    Abstract: Antigen binding constructs that bind to desired targets are disclosed, for example antibodies, including antibody fragments (such as scFv and minibodies) that bind to a target molecule, and have one or more of the disclosed hinges are described herein. Methods of use are described herein.
    Type: Grant
    Filed: August 4, 2016
    Date of Patent: December 21, 2021
    Assignee: IMAGINAB, INC.
    Inventors: Chio Mui Chan, Jean Gudas, Tove Olafsen, Daulet Kadyl Satpayev, Michael Yuri Torgov
  • LOW-VISCOSITY, HIGH CONCENTRATION EVOLOCUMAB FORMULATIONS AND METHODS OF MAKING THE SAME
    Publication number: 20180237501
    Abstract: Provided herein are formulations of PCSK9-binding polypeptides, such as those comprising evolocumab, that comprise N-acetyl arginine and have reduced viscosities when compared to formulations lacking N-acetyl arginine. Provided herein are also methods of formulating such compositions that are advantageous in that they conserve certain components. Such formulations comprising PCSK9-binding polypeptides can be administered to patients to treat and/or prevent PCSK9-related diseases, conditions, and disorders.
    Type: Application
    Filed: February 22, 2018
    Publication date: August 23, 2018
    Applicant: AMGEN INC.
    Inventors: Christopher James SLOEY, Sekhar KANAPURAM, Huanchun CUI, Chio Mui CHAN, Elaheh BINABAJI
  • ANTIGEN BINDING CONSTRUCTS TO TARGET MOLECULES
    Publication number: 20170051044
    Abstract: Antigen binding constructs that bind to desired targets are disclosed, for example antibodies, including antibody fragments (such as scFv and minibodies) that bind to a target molecule, and have one or more of the disclosed hinges are described herein. Methods of use are described herein.
    Type: Application
    Filed: August 4, 2016
    Publication date: February 23, 2017
    Inventors: Chio Mui Chan, Jean Gudas, Tove Olafsen, Daulet Kadyl Satpayev, Michael Yuri Torgov
  • Tent
    Patent number: D775296
    Type: Grant
    Filed: August 23, 2016
    Date of Patent: December 27, 2016
    Inventors: Daniel Shir, Chio Mui Chan