Patents by Inventor Chiu-Ting Fan

Chiu-Ting Fan has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Expression system for enhancing solubility and immunogeneicity of recombinant proteins
    Patent number: 7759461
    Abstract: Expression system for enhancing solubility and immunogenicity of recombinant proteins. The expression system includes a protein expression vector that contains a chimeric gene encoding a chimeric protein comprising: (a) a first polypeptidyl fragment at the N-terminal end of the chimeric protein, containing a protein transduction domain (PTD), or a fragment thereof, having HIV Tat PTD activity; (b) a second polypeptidyl fragment at the C-terminal end of the first polypeptidyl fragment, containing a J-domain, or a fragment thereof, having heat shock protein 70 (Hsp70)-interacting activity; and (c) a third polypeptidyl fragment at the C-terminal end of the second polypeptidyl fragment, containing a target protein or polypeptide.
    Type: Grant
    Filed: March 18, 2009
    Date of Patent: July 20, 2010
    Assignees: Stresspro Biomedicine Incorporation, Animal Technology Institute Taiwan
    Inventors: Ming-Yu Chen, Chin-Kai Chuang, Yu-Hsyu Su, Chiu-Ting Fan, Jung-Chuan Yu, Wen-Chuan Lee
  • EXPRESSION SYSTEM FOR ENHANCING SOLUBILITY AND IMMUNOGENEICITY OF RECOMBINANT PROTEINS
    Publication number: 20090187004
    Abstract: Expression system for enhancing solubility and immunogenicity of recombinant proteins. The expression system includes a protein expression vector that contains a chimeric gene encoding a chimeric protein comprising: (a) a first polypeptidyl fragment at the N-terminal end of the chimeric protein, containing a protein transduction domain (PTD), or a fragment thereof, having HIV Tat PTD activity; (b) a second polypeptidyl fragment at the C-terminal end of the first polypeptidyl fragment, containing a J-domain, or a fragment thereof, having heat shock protein 70 (Hsp70)-interacting activity; and (c) a third polypeptidyl fragment at the C-terminal end of the second polypeptidyl fragment, containing a target protein or polypeptide.
    Type: Application
    Filed: March 18, 2009
    Publication date: July 23, 2009
    Applicants: STRESSPRO BIOMEDICINE INCORPORATION, ANIMAL TECHNOLOGY INSTITUTE TAIWAN
    Inventors: MING-YU CHEN, Chin-Kai Chuang, Yu-Hsyu Su, Chiu-Ting Fan, Jung-Chuan Yu, Wen-Chuan Lee
  • Expression system for enhancing solubility and immunogeneicity of recombinant proteins
    Patent number: 7524648
    Abstract: Expression system for enhancing solubility and immunogenicity of recombinant proteins. The expression system includes a protein expression vector that contains a chimeric gene encoding a chimeric protein. The chimeric protein contains three polypeptidyl fragments: (a) a first polypeptidyl fragment at the N-terminal end of the chimeric protein that contains a protein transduction domain (PTD) or a fragment thereof having HIV Tat PTD activity; (b) a second polypeptidyl fragment at the C-terminal end of the first polypeptidyl fragment that contains a J-domain or a fragment thereof having heat shock protein 70 (Hsp70)-interacting activity; and (c) a third polypeptidyl fragment at the C-terminal end of the second polypeptidyl fragment that contains a target protein or polypeptide.
    Type: Grant
    Filed: May 5, 2008
    Date of Patent: April 28, 2009
    Assignees: Stresspro Biomedicine Incorporation, Animal Technology Institute Taiwan
    Inventors: Ming-Yu Chen, Chin-Kai Chuang, Yu-Hsyu Su, Chiu-Ting Fan, Jung-Chuan Yu, Wen-Chuan Lee
  • Expression system for enhancing solubility and immunogeneicity of recombinant proteins
    Publication number: 20080274508
    Abstract: Expression system for enhancing solubility and immunogenicity of recombinant proteins. The expression system includes a protein expression vector that contains a chimeric gene encoding a chimeric protein. The chimeric protein contains three polypeptidyl fragments: (a) a first polypeptidyl fragment at the N-terminal end of the chimeric protein that contains a protein transduction domain (PTD) or a fragment thereof having HIV Tat PTD activity; (b) a second polypeptidyl fragment at the C-terminal end of the first polypeptidyl fragment that contains a J-domain or a fragment thereof having heat shock protein 70 (Hsp70)-interacting activity; and (c) a third polypeptidyl fragment at the C-terminal end of the second polypeptidyl fragment that contains a target protein or polypeptide.
    Type: Application
    Filed: May 5, 2008
    Publication date: November 6, 2008
    Applicants: STRESSPRO BIOMEDICINE INCORPORATION, ANIMAL TECHNOLOGY INSTITUTE TAIWAN
    Inventors: Ming-Yu Chen, Chin-Kai Chuang, Yu-Hsyu Su, Chiu-Ting Fan, Jung-Chuan Yu, Wen-Chuan Lee