Patents by Inventor Chiu Wo Chau
Chiu Wo Chau has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).
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Publication number: 20190024156Abstract: This invention provides high unit density arrays of microparticles and methods of assembling such arrays. The microparticles in the arrays may be functionalized with chemical or biological entities specific to a given target analyte. The high unit density arrays of this invention are formed on chips which may be combined to form multichip arrays according to the methods described herein. The chips and/or multichip arrays of this invention are useful for chemical and biological assays.Type: ApplicationFiled: September 25, 2018Publication date: January 24, 2019Inventors: Michael Seul, Chiu Wo Chau, Hui Huang, Sukanta Banerjee, Jiacheng Yang, Ye Hong
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Patent number: 10138511Abstract: This invention provides high unit density arrays of microparticles and methods of assembling such arrays. The microparticles in the arrays may be functionalized with chemical or biological entities specific to a given target analyte. The high unit density arrays of this invention are formed on chips which may be combined to form multichip arrays according to the methods described herein. The chips and/or multichip arrays of this invention are useful for chemical and biological assays.Type: GrantFiled: March 29, 2017Date of Patent: November 27, 2018Assignee: BioArray Solutions Ltd.Inventors: Michael Seul, Chiu Wo Chau, Hui Huang, Sukanta Banerjee, Jiacheng Yang, Ye Hong
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Publication number: 20170260577Abstract: This invention provides high unit density arrays of microparticles and methods of assembling such arrays. The microparticles in the arrays may be functionalized with chemical or biological entities specific to a given target analyte. The high unit density arrays of this invention are formed on chips which may be combined to form multichip arrays according to the methods described herein. The chips and/or multichip arrays of this invention are useful for chemical and biological assays.Type: ApplicationFiled: March 29, 2017Publication date: September 14, 2017Inventors: Michael Seul, Chiu Wo Chau, Hui Huang, Sukanta Banerjee, Jiacheng Yang, Ye Hong
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Patent number: 9611507Abstract: This invention provides high unit density arrays of microparticles and methods of assembling such arrays. The microparticles in the arrays may be functionalized with chemical or biological entities specific to a given target analyte. The high unit density arrays of this invention are formed on chips which may be combined to form multichip arrays according to the methods described herein. The chips and/or multichip arrays of this invention are useful for chemical and biological assays.Type: GrantFiled: September 15, 2014Date of Patent: April 4, 2017Assignee: BioArray Solutions, Ltd.Inventors: Michael Seul, Chiu Wo Chau, Hui Huang, Sukanta Banerjee, Jiacheng Yang, Ye Hong
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Publication number: 20150126407Abstract: This invention provides high unit density arrays of microparticles and methods of assembling such arrays. The microparticles in the arrays may be functionalized with chemical or biological entities specific to a given target analyte. The high unit density arrays of this invention are formed on chips which may be combined to form multichip arrays according to the methods described herein. The chips and/or multichip arrays of this invention are useful for chemical and biological assays.Type: ApplicationFiled: September 15, 2014Publication date: May 7, 2015Inventors: Michael Seul, Chiu Wo Chau, Hui Huang, Sukanta Banerjee, Jiacheng Yang, Ye Hong
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Patent number: 8999731Abstract: The present application provides a set of fundamental operations enabling interactive control over the creation and placement of planar arrays of several types of particles and biomolecules and the manipulation of array shape and size. The present invention enables sample preparation and handling for diagnostic assays and biochemical analysis in an array format, and the functional integration of these operations. In addition, the present invention provides a procedure for the creation of material surfaces with desired properties and for the fabrication of surface-mounted optical components.Type: GrantFiled: December 21, 2011Date of Patent: April 7, 2015Assignee: BioArray Solutions, Ltd.Inventors: Michael Seul, Chiu Wo Chau
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Patent number: 8615367Abstract: Disclosed is number coding of pairs (“doublets”) or small sets (“multiplets”) of solid phase carriers which provides distinguishable subtypes of a given type of such carriers, where each carrier type is distinguishable on the bases of a different code. Such number coding is useful for augmenting a coding system, such as a color code, and thereby effectively multiplying the number of “colors” (distinguishable sub-types). It can be applied, for example, to determine whether a sample is homozygous or heterozygous at a number of different sites for one of two different alleles, where the same color code is applied for each of the two alleles, and the alleles with the same color code are distinguished by knowing how many carriers are associated with molecules which detect each different allele.Type: GrantFiled: March 24, 2011Date of Patent: December 24, 2013Assignee: Bioarray Solutions, Ltd.Inventors: Michael Seul, Chiu Wo Chau, Enqing Tan
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Publication number: 20120220495Abstract: This invention provides high unit density arrays of microparticles and methods of assembling such arrays. The microparticles in the arrays may be functionalized with chemical or biological entities specific to a given target analyte. The high unit density arrays of this invention are formed on chips which may be combined to form multichip arrays according to the methods described herein. The chips and/or multichip arrays of this invention are useful for chemical and biological assays.Type: ApplicationFiled: May 7, 2012Publication date: August 30, 2012Applicant: BioArray Solutions, Ltd.Inventors: Michael Seul, Chiu Wo Chau, Hui Huang, Sukanta Banerjee, Jiacheng Yang, Ye Hong
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Publication number: 20120157346Abstract: The present application provides a set of fundamental operations enabling interactive control over the creation and placement of planar arrays of several types of particles and biomolecules and the manipulation of array shape and size. The present invention enables sample preparation and handling for diagnostic assays and biochemical analysis in an array format, and the functional integration of these operations. In addition, the present invention provides a procedure for the creation of material surfaces with desired properties and for the fabrication of surface-mounted optical components.Type: ApplicationFiled: December 21, 2011Publication date: June 21, 2012Inventors: Michael Seul, Chiu Wo Chau
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Patent number: 8084274Abstract: An apparatus providing programmable illumination pattern generation for the manipulation of colloidal particulates and biomolecules in suspension between electrodes is disclosed. The apparatus implements LEAPS (light-controlled electrokinetic assembly of particles near surfaces), which relies on AC electric field-induced assembly of particles, patterning of an electrolyte/silicon oxide/silicon interface to exert spatial control over the assembly process, and real-time control of assembly via external illumination. The apparatus generates patterns of illumination and projects them onto planar surfaces, i.e., LEAPS electrodes.Type: GrantFiled: February 11, 2008Date of Patent: December 27, 2011Assignee: BioArray Solutions, Ltd.Inventors: Michael Seul, Chiu Wo Chau
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Publication number: 20110098201Abstract: This invention provides high unit density arrays of microparticles and methods of assembling such arrays. The microparticles in the arrays may be functionalized with chemical or biological entities specific to a given target analyte. The high unit density arrays of this invention are formed on chips which may be combined to form multichip arrays according to the methods described herein. The chips and/or multichip arrays of this invention are useful for chemical and biological assays.Type: ApplicationFiled: October 22, 2010Publication date: April 28, 2011Applicant: BioArray Solutions, Ltd.Inventors: Michael Seul, Chiu Wo Chau, Hui Huang, Sukanta Banerjee, Jiacheng Yang, Ye Hong
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Patent number: 7842649Abstract: This invention provides high unit density arrays of microparticles and methods of assembling such arrays. The microparticles in the arrays may be functionalized with chemical or biological entities specific to a given target analyte. The high unit density arrays of this invention are formed on chips which may be combined to form multichip arrays according to the methods described herein. The chips and/or multichip arrays of this invention are useful for chemical and biological assays.Type: GrantFiled: October 18, 2007Date of Patent: November 30, 2010Assignee: BioArray Solutions, Ltd.Inventors: Michael Seul, Chiu Wo Chau, Hui Huang, Sukanta Banerjee, Jiacheng Yang, Ye Hong
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Publication number: 20080173544Abstract: An apparatus providing programmable illumination pattern generation for the manipulation of colloidal particulates and biomolecules in suspension between electrodes, is disclosed. The apparatus implements LEAPS (Light-controlled electrokinetic assembly of particles near surfaces), which relies on: AC electric field-induced assembly of particles: the patterning of the electrolyte/silicon oxide/silicon interface to exert spatial control over the assembly process; and the real-time control of the assembly process via external illumination. The apparatus generates patterns of illumination and projects them onto planar surfaces. i.e., a LEAPS electrode.Type: ApplicationFiled: February 11, 2008Publication date: July 24, 2008Inventors: Michael Seul, Chiu Wo Chau
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Patent number: 7390676Abstract: A method and apparatus for the manipulation of colloidal particulates and biomolecules at the interface between an insulating electrode such as silicon oxide and an electrolyte solution. Light-controlled electrokinetic assembly of particles near surfaces relies on the combination of three functional elements: the AC electric field-induced assembly of planar aggregates; the patterning of the electrolyte/silicon oxide/silicon interface to exert spatial control over the assembly process; and the real-time control of the assembly process via external illumination. The present invention provides a set of fundamental operations enabling interactive control over the creation and placement of planar arrays of several types of particles and biomolecules and the manipulation of array shape and size. The present invention enables sample preparation and handling for diagnostic assays and biochemical analysis in an array format, and the functional integration of these operations.Type: GrantFiled: July 21, 2003Date of Patent: June 24, 2008Assignee: BioArray Solutions Ltd.Inventors: Michael Seul, Chiu Wo Chau
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Publication number: 20080123089Abstract: This invention provides high unit density arrays of microparticles and methods of assembling such arrays. The microparticles in the arrays may be functionalized with chemical or biological entities specific to a given target analyte. The high unit density arrays of this invention are formed on chips which may be combined to form multichip arrays according to the methods described herein. The chips and/or multichip arrays of this invention are useful for chemical and biological assays.Type: ApplicationFiled: October 18, 2007Publication date: May 29, 2008Inventors: Michael Seul, Chiu Wo Chau, Hui Huang, Sukanta Banerjee, Jiacheng Yang, Ye Hong
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Patent number: 7358097Abstract: Disclosed is an apparatus and method of maintaining chips or arrays of particles, or arrays of particles deposited on chip surfaces, in a designated area on a substrate surface. This is accomplished by having hydrophilic chips or arrays of particles, and a substrate which has a series of hydrophilic regions designed to accommodate the chips/arrays of particles, surrounded by hydrophobic regions. In the presence of aqueous solution, the chips or arrays of particles are held in the designated regions.Type: GrantFiled: September 5, 2003Date of Patent: April 15, 2008Assignee: Bio Array Solutions Ltd.Inventors: Michael Seul, Chiu Wo Chau
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Patent number: 7335153Abstract: This invention provides high unit density arrays of microparticles and methods of assembling such arrays. The microparticles in the arrays may be functionalized with chemical or biological entities specific to a given target analyte. The high unit density arrays of this invention are formed on chips which may be combined to form multichip arrays according to the methods described herein. The chips and/or multichip arrays of this invention are useful for chemical and biological assays.Type: GrantFiled: July 9, 2002Date of Patent: February 26, 2008Assignee: Bio Array Solutions Ltd.Inventors: Michael Seul, Chiu Wo Chau, Hui Huang, Sukanta Banerjee, Jiacheng Yang, Ye Hong
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Patent number: 7156315Abstract: A method and apparatus for the manipulation of colloidal particulates and biomolecules at the interface between an insulating electrode such as silicon oxide and an electrolyte solution. Light-controlled electrokinetic assembly of particles near surfaces relies on the combination of three functional elements: the AC electric field-induced assembly of planar aggregates; the patterning of the electrolyte/silicon oxide/silicon interface to exert spatial control over the assembly process; and the real-time control of the assembly process via external illumination. The present invention provides a set of fundamental operations enabling interactive control over the creation and placement of planar arrays of several types of particles and biomolecules and the manipulation of array shape and size. The present invention enables sample preparation and handling for diagnostic assays and biochemical analysis in an array format, and the functional integration of these operations.Type: GrantFiled: February 13, 2003Date of Patent: January 2, 2007Assignee: BioArray Solutions, Ltd.Inventors: Michael Seul, Chiu Wo Chau
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Patent number: 7144119Abstract: An apparatus providing programmable illumination pattern generation for the manipulation of colloidal particulates and biomolecules in suspension between electrodes, is disclosed. The apparatus implements LEAPS (Light-controlled electrokinetic assembly of particles near surfaces), which relies on: AC electric field-induced assembly of particles the patterning of the electrolyte/silicon oxide/silicon interface to exert spatial control over the assembly process; and the real-time control of the assembly process via external illumination. The apparatus generates patterns of illumination and projects then onto planar surfaces, i.e., a LEAPS electrode.Type: GrantFiled: January 24, 2001Date of Patent: December 5, 2006Assignee: BioArray Solutions Ltd.Inventors: Michael Seul, Chiu Wo Chau
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Patent number: 7057704Abstract: An apparatus providing programmable illumination pattern generation for the manipulation of colloidal particulates and biomolecules in suspension between electrodes, is disclosed. The apparatus implements LEAPS (Light-controlled electrokinetic assembly of particles near surfaces), which relies on: AC electric field-induced assembly of particles: the patterning of the electrolyte/silicon oxide/silicon interface to exert spatial control over the assembly process; and the real-time control of the assembly process via external illumination. The apparatus generates patterns of illumination and projects them on to planar surfaces. i.e., a LEAPS electrode.Type: GrantFiled: March 16, 2002Date of Patent: June 6, 2006Assignee: BioArray Solutions Ltd.Inventors: Michael Seul, Chiu Wo Chau