Abstract: Methods of modulating transcription of a target gene in a cell (which may be in vitro or in vivo) are provided. Aspects of the methods employ a transcription factor-chemical inducer of proximity (TF-CIP) system to modulate, e.g., enhance or reduce, transcription of a target gene in a cell. Embodiments of the methods include providing in a cell a chemical inducer of proximity (CIP) which links a first endogenous anchor transcription factor that binds to a promoter of the target gene and a second endogenous transcription modulating factor (e.g., a transcription factor or transcription repressor), wherein CIP mediated linkage of the anchor transcription factor and transcription modulating factor modulates transcription of the target gene in the cell. Also provided are compositions that find use in practicing methods of the invention.

Abstract: An opening structure of image device comprises a body, at least a sliding track, at least a sliding sleeve, and a shield, wherein the sliding sleeve slide on the sliding track in order to drive synchronously the shield to achieve opening or closing status. Furthermore, the image device is entirely enclosed into the shield so as to prevent the image device from dust pollution and unexpected damage when the shield is at closing status. Meanwhile, the shield can be designed to be a special look, which will bring to user a fashionable feeling.

Abstract: An opening structure of image device comprises a body, at least a sliding track, at least a sliding sleeve, and a shield, wherein the sliding sleeve slide on the sliding track in order to drive synchronously the shield to achieve opening or closing status. Furthermore, the image device is entirely enclosed into the shield so as to prevent the image device from dust pollution and unexpected damage when the shield is at closing status. Meanwhile, the shield can be designed to be a special look, which will bring to user a fashionable feeling.

Abstract: An opening structure of image device comprises a body, at least a sliding track, at least a sliding sleeve, and a shield, wherein the sliding sleeve slide on the sliding track in order to drive synchronously the shield to achieve opening or closing status. Furthermore, the image device is entirely enclosed into the shield so as to prevent the image device from dust pollution and unexpected damage when the shield is at closing status. Meanwhile, the shield can be designed to be a special look, which will bring to user a fashionable feeling.