Patents by Inventor Chizuru Nagayoshi

Chizuru Nagayoshi has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • RNA in situ hybridization
    Patent number: 9051610
    Abstract: A method for identifying the presence of a target gene mRNA is provided, which involves hybridizing one or more oligonucleic acid probes with the target gene mRNA expressed in a tissue sample, and detecting a low-molecular-weight compound label added to at least one of the bases of the oligonucleic acid probes. The oligonucleic acid probes are contacted with the tissue sample for hybridization with the target gene mRNA after pretreating (prehybridizing) one or more dummy oligonucleic acids with the tissue sample, or a mixture of the oligonucleic acid probes and the dummy oligonucleic acids is contacted with the sample tissue to hybridize the oligonucleic acid probes with the target gene mRNA.
    Type: Grant
    Filed: May 19, 2009
    Date of Patent: June 9, 2015
    Assignee: CELISH FD, INC.
    Inventors: Hirofumi Doi, Masahiro Matsuoka, Tatsuhiro Nakano, Chizuru Nagayoshi
  • RNA IN SITU HYBRIDIZATION
    Publication number: 20110183331
    Abstract: Disclosed is a method for identifying the presence of a target gene mRNA, which comprises hybridizing one or more oligonucleic acid probes with the target gene mRNA expressed in a tissue sample, and detecting a low-molecular-weight compound label added to at least one of the bases of the oligonucleic acid probes, wherein the oligonucleic acid probes are contacted with the tissue sample for hybridization with the target gene mRNA after pretreating (prehybridizing) one or more dummy oligonucleic acids with the tissue sample, or a mixture of the oligonucleic acid probes and the dummy oligonucleic acids is contacted with the sample tissue to hybridize the oligonucleic acid probes with the target gene mRNA, and wherein the dummy oligonucleic acids are substantially equal in length with the oligonucleic acid probes, and are neither hybridizable with regions of the target gene mRNA with which the oligonucleic acid probes hybridize nor with the oligonucleic acid probes.
    Type: Application
    Filed: May 19, 2009
    Publication date: July 28, 2011
    Applicant: Celish FD, INC.
    Inventors: Hirofumi Doi, Masahiro Matsuoka, Tatsuhiro Nakano, Chizuru Nagayoshi