Abstract: A method of analysing the magnitude of Magnetic Resonance Imaging (MRI) data is described. The method comprising: using the magnitude only of the multi-echo MRI data of images from the subject, where images are acquired at arbitrarily timed echoes including at least one echo time where water and fat are not substantially in-phase; fitting the magnitude of said multi-echo MRI data to a single signal model to produce a plurality of potential solutions for the relative signal contributions for each of the at least two species from the model, by using a plurality of different starting conditions to generate a particular cost function value for each of the plurality of starting conditions, where said cost function values are independent of a field map term for the MRI data; analysing said cost function values to calculate relative signal separation contribution for each species at each voxel of the images.

Abstract: A method of quantifying changes in a visceral organ comprises acquiring first (310) and second (410) medical scans of a visceral organ at first and second timepoints. At least part of the visceral organ in the first medical scan is parcellated into a first set of one or more subregions (420), based on image content, each subregion comprising a plurality of voxels. The first medical scan (310) is aligned to the second medical scan (410), before or after parcellating the first medical scan (310). Then the second medical scan is parcellated into a second set of one or more subregions. A metric is evaluated for a subregion in the first medical scan (310), and for the corresponding subregion in the second medical scan (410). A difference in the metric values provides a measure of a change that has occurred in the subregion, between the first and second timepoints.

Abstract: A method of analysing the magnitude of Magnetic Resonance Imaging (MRI) data is described. The method comprising: using the magnitude only of the multi-echo MRI data of images from the subject, where images are acquired at arbitrarily timed echoes including at least one echo time where water and fat are not substantially in-phase; fitting the magnitude of said multi-echo MRI data to a single signal model to produce a plurality of potential solutions for the relative signal contributions for each of the at least two species from the model, by using a plurality of different starting conditions to generate a particular cost function value for each of the plurality of starting conditions, where said cost function values are independent of a field map term for the MRI data; analysing said cost function values to calculate relative signal separation contribution for each species at each voxel of the images.

Abstract: A method of quantifying changes in a visceral organ comprises acquiring first (310) and second (410) medical scans of a visceral organ at first and second timepoints. At least part of the visceral organ in the first medical scan is parcellated into a first set of one or more subregions (420), based on image content, each subregion comprising a plurality of voxels. The first medical scan (310) is aligned to the second medical scan (410), before or after parcellating the first medical scan (310). Then the second medical scan is parcellated into a second set of one or more subregions. A metric is evaluated for a subregion in the first medical scan (310), and for the corresponding subregion in the second medical scan (410). A difference in the metric values provides a measure of a change that has occurred in the subregion, between the first and second timepoints.