Abstract: Compounds of Formula I, as shown below and defined herein: and pharmaceutically acceptable salts, syntheses, intermediates, formulations, and methods of treating diseases including cancer, inflammation, and autoimmune disease mediated at least in part by Bruton's Tyrosine Kinase (BTK).

Abstract: Provided herein are N-(2-aminophenyl)-prop-2-enamide derivatives, such as those of Formula (I), methods for the synthesis thereof, and uses thereof in the treatment of cancer, such as SALL4-expressing cancer, in a cell or subject in need thereof.

Abstract: The present invention provides a direct current circuit breaker and its implementation method, which includes a cutout circuit, a commutation circuit and a energy absorption circuit connected in parallel. Through using power semiconductor switch module to cut off the current, it will have a quickly action, without generating electric arc, while the modular construction also reduces the consistency requirements of the power electronic component.

Abstract: A multi-stream service concurrent transmission method includes: a multi-interface terminal initiating a service transmission request to a network side; the multi-interface terminal receiving information of database servers capable of providing the requested service resources and service information of the requested service; the multi-interface terminal establishing a plurality of concurrent links with the database servers, dividing service data packets of the requested service, and notifying the network side of the division result; the multi-interface terminal receiving the service data packets of the requested service via the plurality of established concurrent links. The embodiment of the present document further correspondingly discloses a multi-stream service concurrent transmission subsystem, system and a multi-interface terminal.

Abstract: A device and service discovery method and a piece of device middleware are provided.

Abstract: The present invention discloses a method of data retransmission in coordination service transmission and access network gateway thereof. Wherein, the method includes: in coordination service transmission, access network gateway receives the service data requested by the coordination terminal, caches the data and transmits it to the corresponding destination terminal; the access network gateway executes retransmission strategy, and when decides data retransmission is needed, retransmits the cached data to the corresponding destination terminal. The access network gateway is used to receive the service data requested by the coordination terminal, to cache the data and transmit it to the corresponding destination terminal, to retransmit the cached data to the corresponding destination terminal when data retransmission is needed. Using the present invention, to the problem of service data retransmission in coordination service transmission, the service data transmission efficiency is effectively improved.

Abstract: A method and an apparatus for a coexistence of an M2M service and an H2H service relate to the technical field of wireless communication. The method includes: during an implementation of an M2M service, determining whether the M2M service is a QoS negotiable M2M service by checking a type of the M2M service; when it is determined that the M2M service is a QoS negotiable M2M service, making the M2M service and an H2H service to share same network resources; and when it is determined that the M2M service is a QoS non-negotiable M2M service, configuring, for the M2M service, a dedicated cell dedicated to implement the M2M service, wherein, the M2M service is a machine to machine service, and the H2H service is a human to human service.

Abstract: The present disclosure discloses a method for synchronous service-flow transmission in a heterogeneous network, including that: an access point collects a parameter on a wireless-network channel, and reports the parameter to a synchronization managing unit of an access-network controller; the synchronization managing unit dynamically adjusts the received parameter on the wireless-network channel, and transmits the adjusted parameter to each service-flow channel to implement synchronization between different service-flows. The present disclosure also provides a system for synchronous service-flow transmission in a heterogeneous network. With a technical solution of the present disclosure, it is possible to implement synchronous service-flow transmission and reduce delay while increasing a system throughput.

Abstract: The present disclosure provides an adaptation, shunt transmission and stream switching method and system for a coordinated service, and the method includes: a request message for service transmission is received from a terminal group; user context information, terminal context information and service context information are acquired according to the request message, and a service adaptation strategy and a service shunt strategy are established; the service adaptation strategy and the service shunt strategy are implemented, adaptation of the coordinated service is completed, and a shunt transmission of the coordinated service is performed; and during the shunt transmission, when a stream switching triggering condition is determined according to acquired network context information and terminal context information, the service shunt strategy and/or the service adaption strategy are updated according to a corresponding stream switching type, and a transmission path of a service stream is redirected.

Abstract: A method and an apparatus for a coexistence of an M2M service and an H2H service relate to the technical field of wireless communication. The method includes: during an implementation of an M2M service, determining whether the M2M service is a QoS negotiable M2M service by checking a type of the M2M service; when it is determined that the M2M service is a QoS negotiable M2M service, making the M2M service and an H2H service to share same network resources; and when it is determined that the M2M service is a QoS non-negotiable M2M service, configuring, for the M2M service, a dedicated cell dedicated to implement the M2M service, wherein, the M2M service is a machine to machine service, and the H2H service is a human to human service.

Abstract: An authentication method and system oriented to a heterogeneous network are disclosed. After receiving a service request sent by a virtual terminal, a unified authentication platform generates a service token according to the service request, and sends the service token to the virtual terminal and a target network; the virtual terminal submits the service token to the target network, and requests the target network to provide service data; and the target network compares the service token submitted by the virtual terminal with the service token sent to the target network by the unified authentication platform, and provides the service data to the virtual terminal when the service token submitted by the virtual terminal is consistent with the service token sent to the target network by the unified authentication platform.

Abstract: Disclosed in the embodiments of the present invention are a method, device and system for mobility management as well as a computer storage medium. The method comprises: reception by an MME of a service command and extraction from same of service information; determining on the basis of said information which wireless networks are accessed by each terminal of a terminal cluster; invoking, on the basis of the wireless network accessed by each terminal of a terminal cluster, the service requested by each such terminal of a terminal cluster.

Abstract: Disclosed is a method for mobility management of group terminals, where a mobility management platform sends a request for calling a service to a terminal of a group, and determines a terminal responding to the request for calling the service as a service center of the service; and the service center of the service configures a terminal environment according to the request for calling the service to which the service center of the service responds, and uploads information on the configured terminal environment to the mobility management platform. Also disclosed are a system and equipments for mobility management of group terminals.

Abstract: A multi-stream service concurrent transmission method includes: a multi-interface terminal initiating a service transmission request to a network side; the multi-interface terminal receiving information of database servers capable of providing the requested service resources and service information of the requested service; the multi-interface terminal establishing a plurality of concurrent links with the database servers, dividing service data packets of the requested service, and notifying the network side of the division result; the multi-interface terminal receiving the service data packets of the requested service via the plurality of established concurrent links. The embodiment of the present document further correspondingly discloses a multi-stream service concurrent transmission subsystem, system and a multi-interface terminal.

Abstract: The present invention provides a direct current circuit breaker and its implementation method, which includes the cutout circuit, the commutation circuit and the energy absorption circuit connected in parallel, wherein the cutout circuit includes cutout inductance and cutout unit connected in series, the commutation circuit includes commutation inductance, commutation unit and mechanical switch connected in series, commutation unit has a smaller on-resistance compared to cutout unit. The direct current circuit breaker topology of the present invention is novelty, concise, fully functional, easy to control and can flexible extend to apply to different voltage occasion.

Abstract: The present invention discloses a method of data retransmission in coordination service transmission and access network gateway thereof. Wherein, the method includes: in coordination service transmission, access network gateway receives the service data requested by the coordination terminal, caches the data and transmits it to the corresponding destination terminal; the access network gateway executes retransmission strategy, and when decides data retransmission is needed, retransmits the cached data to the corresponding destination terminal. The access network gateway is used to receive the service data requested by the coordination terminal, to cache the data and transmit it to the corresponding destination terminal, to retransmit the cached data to the corresponding destination terminal when data retransmission is needed. Using the present invention, to the problem of service data retransmission in coordination service transmission, the service data transmission efficiency is effectively improved.

Abstract: A device and service discovery method and a piece of device middleware are provided.

Abstract: The present invention provides to a default current testing method of the high voltage direct current converter valve composited by impulse voltage. The technical scheme of the invention composites the symmetrical positive and negative voltage and the impulse into asymmetric positive and negative high voltage, it makes the test valve voltage accurately achieve required peak value at the set time. The test circuit is simple relatively; the high voltage source of the default current test circuit is instead by surge generators. The test method is flexible, safe, and suitable for different DC project converter valves.