Patents by Inventor Chong Mei KOH

Chong Mei KOH has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Methods for tuning carotenoid production levels and compositions in and genera
    Patent number: 10308691
    Abstract: The present invention relates to the field of fungal biotechnology, more particularly to genetic engineering methods for the production of carotenoids in fungal hosts selected from Rhodospordium and Rhodotorula genera.
    Type: Grant
    Filed: December 14, 2015
    Date of Patent: June 4, 2019
    Assignee: TEMASEK LIFE SCIENCES LABORATORY LIMITED
    Inventors: Yanbin Liu, Chong Mei Koh, Lianghui Ji
  • Methods for efficient production of polyunsaturated fatty acids (PUFA) in and species
    Patent number: 10081821
    Abstract: The present invention relates to the field of fungal biotechnology, more particularly to genetic engineering methods for the production of polyunsaturated fatty acids (PUFA) in fungal hosts selected from Rhodosporidium and Rhodotorula genera. The present invention further relates to a modified fungal host cell having reduced native aldehyde dehydrogenase (ALD 1) enzyme activity, and methods for producing omega-3 and omega-6 fatty acids and triacylglycerides, by growing said fungal host cell under suitable conditions.
    Type: Grant
    Filed: August 21, 2015
    Date of Patent: September 25, 2018
    Assignee: TEMASEK LIFE SCIENCES LABORATORY LIMITED
    Inventors: Yanbin Liu, Chong Mei Koh, Lianghui Ji
  • METHODS FOR TUNING CAROTENOID PRODUCTION LEVELS AND COMPOSITIONS IN RHODOSPORIDIUM AND RHODOTORULA GENERA
    Publication number: 20170362285
    Abstract: The present invention relates to the field of fungal biotechnology, more particularly to genetic engineering methods for the production of carotenoids in fungal hosts selected from Rhodospordium and Rhodotorula genera.
    Type: Application
    Filed: December 14, 2015
    Publication date: December 21, 2017
    Applicant: TEMASEK LIFE SCIENCES LABORATORY LIMITED
    Inventors: Yanbin LIU, Chong Mei KOH, Lianghui JI
  • METHODS FOR EFFICIENT PRODUCTION OF POLYUNSATURATED FATTY ACIDS(PUFA) IN RHODOSPORIDIUM AND RHODOTORULA SPECIES
    Publication number: 20170198315
    Abstract: The present invention relates to the field of fungal biotechnology, more particularly to genetic engineering methods for the production of polyunsaturated fatty acids (PUFA) in fungal hosts selected from Rhodosporidium and Rhodotorula genera. The present invention further relates to a modified fungal host cell having reduced native aldehyde dehydrogenase (ALD 1) enzyme activity, and methods for producing omega-3 and omega-6 fatty acids and triacylglycerides, by growing said fungal host cell under suitable conditions.
    Type: Application
    Filed: August 21, 2015
    Publication date: July 13, 2017
    Applicant: Temasek Life Sciences Laboratory Limited
    Inventors: Yanbin LIU, Chong Mei KOH, Lianghui JI
  • Genetic manipulation and expression systems for Pucciniomycotina and Ustilaginomycotina subphyla
    Patent number: 9631196
    Abstract: The present invention relates to the application of isolated promoters and synthetic dominant selection constructs and enhancers for gene targeting for efficient production of genetically modified cells in a species selected from the Pucciniomycotina and Ustilaginomycotina subphyla, in particular, species selected from the Rhodosporidium, Sporisorium, Sporobolomyces or Ustilago genera.
    Type: Grant
    Filed: May 10, 2012
    Date of Patent: April 25, 2017
    Assignee: TEMASEK LIFE SCIENCES LABORATORY LIMITED
    Inventors: Liang Hui Ji, Yan Bin Liu, John Chong Mei Koh, Long Hua Sun
  • GENETIC MANIPULATION AND EXPRESSION SYSTEMS FOR PUCCINIOMYCOTINA AND USTILAGINOMYCOTINA SUBPHYLA
    Publication number: 20140113377
    Abstract: The present invention relates to the application of isolated promoters and synthetic dominant selection constructs and enhancers for gene targeting for efficient production of genetically modified cells in a species selected from the Pucciniomycotina and Ustilaginomycotina subphyla, in particular, species selected from the Rhodosporidium, Sporisorium, Sporobolomyces or Ustilago genera.
    Type: Application
    Filed: May 10, 2012
    Publication date: April 24, 2014
    Applicant: TEMASEK LIFE SCIENCES LABORATORY LIMITED
    Inventors: Liang Hui Ji, Yan Bin Liu, John Chong Mei Koh, Long Hua Sun