Abstract: Systems and methods for generating a remodeling plan for a property are disclosed. An exemplary system includes a communication interface configured to receive a floor plan of the property and a remodeling preference. The system further includes at least one processor configured to obtain structural data of the property based on the floor plan and obtain a neural network model based on the remodeling preference. The neural network model is trained using sample floor plans and sample remodeling data for the remodeling preference. The at least one processor is further configured to learn structural remodeling information based on the floor plan and the structural data using the neural network model. The at least one processor is also configured to generate the remodeling plan for the property based on the structural remodeling information. The remodeling plan identifies one or more structures in the floor plan for remodeling.

Abstract: The present application relates to the field of pharmaceutical preparations and relates to [1,2,4]triazolo [1,5-a]pyridine compounds and their isomers or pharmaceutically acceptable salts or their crystal forms, as well as local topical preparations and their applications in skin diseases. Specifically, it relates to a local topical formulations of compound (S)—N-(5-(2-(2,2-difluorocyclopropanecarbonyl)-2-nitrospiro[3.5]non-7-yl)-[1,2,4-triazole[1,5-a]pyridine-2-yl) cyclopropaneformamide and its isomers or pharmaceutically acceptable salts or crystal forms, and their applications in skin diseases. The preferred skin diseases include psoriasis, atopic dermatitis, vitiligo, lupus erythematosus, alopecia areata, eczema, contact dermatitis, urticaria, pompholyxs, dermatomyositis, scleroderma, acne, and seborrheic dermatitis.

Abstract: A crystal form (such as formula I) of a 2-methyl-2-propanol and amino-substituted aryl compound and a preparation method therefor. Also provided is an application of the crystal form in the preparation of a medicine for treating related diseases.

Abstract: An aminopyridine compound that may be used as an aldehyde trapping agent, and specifically disclosed is a compound represented by formula (I) and a pharmaceutically acceptable salt thereof.

Abstract: A crystal form (such as formula I) of a 2-methyl-2-propanol and amino-substituted aryl compound and a preparation method therefor. Also provided is an application of the crystal form in the preparation of a medicine for treating related diseases.

Abstract: Provided are a method and an apparatus for displaying item information in a current space, an electronic device, and a non-transitory machine-readable storage medium. The method comprises: obtaining spatial data of a current position in a current space, and obtaining position data and information data of at least one item in the current space according to the spatial data; calculating a display priority of the at least one item in the current space according to the spatial data, the position data, and the information data; and displaying the information data of the at least one item according to the display priority. Through the method, the display priority of the information data of the at least one item in the current space are calculated, and then the information data of the at least one item in the current space is displayed according to the display priority, so that it is convenient for a user to directly view the information data of the at least one item in the current space.

Abstract: Systems and methods for visualizing furnishing objects in a property are disclosed. An exemplary system includes a communication interface configured to receive a depth image of an interior space of the property captured by a 3D scanner and the depth image includes one or more existing furnishing objects in the interior space. The system further includes at least one processor configured to remove at least one existing furnishing object from the depth image, leaving at least one hole in the depth image corresponding to where the removed existing furnishing object used to be. The at least one processor is further configured to restore the depth image by filling the at least one hole in the depth image with a scene of the interior space that was blocked by the removed existing furnishing object, using a first neural network model trained with an image inpainting algorithm.

Abstract: Systems and methods for generating a remodeling plan for a property are disclosed. An exemplary system includes a communication interface configured to receive a floor plan of the property and a remodeling preference. The system further includes at least one processor configured to obtain structural data of the property based on the floor plan and obtain a neural network model based on the remodeling preference. The neural network model is trained using sample floor plans and sample remodeling data for the remodeling preference. The at least one processor is further configured to learn structural remodeling information based on the floor plan and the structural data using the neural network model. The at least one processor is also configured to generate the remodeling plan for the property based on the structural remodeling information. The remodeling plan identifies one or more structures in the floor plan for remodeling.

Abstract: The present invention relates to a method for identifying parameters of a 10 kV static load model based on similar daily load curves. In the present invention, an optimization model for identifying full-period parameters of the static load model is proposed based on a large number of daily load curves with response characteristic, a structure and constraints of the static load model, and two theoretical basic assumptions about loads. Full-period (including 96 moments) static voltage model parameters of 10 kV loads are given through optimization solution. A rule that active power and reactive power of the loads at each moment change with voltage is obtained. In addition, a change rule of load constituents is obtained. The method delivers good applicability, satisfies actual demands, and is suitable for large-scale static model analyses for 10 kV loads.

Abstract: Provided are a method and an apparatus for displaying item information in a current space, an electronic device, and a non-transitory machine-readable storage medium. The method comprises: obtaining spatial data of a current position in a current space, and obtaining position data and information data of at least one item in the current space according to the spatial data; calculating a display priority of the at least one item in the current space according to the spatial data, the position data, and the information data; and displaying the information data of the at least one item according to the display priority. Through the method, the display priority of the information data of the at least one item in the current space are calculated, and then the information data of the at least one item in the current space is displayed according to the display priority, so that it is convenient for a user to directly view the information data of the at least one item in the current space.

Abstract: The present invention relates to polydixylitol polymer based gene transporter (PdXYP) and a preparation method thereof. Further, the present invention relates to a nucleic acid delivery complex where the nucleic acids for treatment are conjugated to the gene transporter and a pharmaceutical composition for gene therapy including the complex as an active ingredient. In addition, the present invention relates to the gene transporter, gene delivery complex, and gene therapy using the gene transporter and gene delivery complex. It was confirmed that the PdXYP of the present invention has a considerably higher nucleic acid delivery rate than existing gene transporters, has almost no cytotoxicity in the conjugate when conjugated with DNA, also has very high in vivo transfection efficiency, and above all, especially has considerably high transfection efficiency for brain tissues, which has involved difficulty in gene therapy due to the blood brain barrier for a while.

Abstract: The present disclosure relates to a thiolated hydroxypropyl methylcellulose phthalate (T-HPMCP) drug delivery vehicle which is pH responsive and is loaded with either a protein drug or an antigen, to T-HPMCP microparticles, and to a production method for an ileum-specific, pH responsive, T-HPMCP drug delivery vehicle, the method including a step of loading a protein drug or an antigen onto the T-HPMCP microparticles. The T-HPMCP microparticles of the present disclosure are soluble in chlorinated methane because of the introduction of the thiol group, while a T-HPMCP drug delivery vehicle produced from the particles can efficiently effect in vivo delivery of the protein drug or antigen which is loaded thereon, since said vehicle is pH responsive such that the in vivo residence time is extended and the vehicle can act specifically on the ileum.

Abstract: The present invention uses the principles of electrochemical ion absorption (charging) and ion desorption (discharge), and relates to a continuous flow-electrode system, a high-capacity energy storage system, and a water treatment method using the same, in which high-capacity electric energy is stored as electrode materials of a slurry phase and electrolytes simultaneously flow in a successive manner within a fine flow channel structure formed on an electrode. More specifically, the present invention relates to a continuous flow-electrode system, an energy storage system, and a water treatment method, wherein electrode active materials consecutively flow in a slurry state whereby a high capacity is easily obtained without enlarging or stacking electrodes.

Abstract: The present invention relates to polydixylitol polymer based gene transporter (PdXYP) and a preparation method thereof. Further, the present invention relates to a nucleic acid delivery complex where the nucleic acids for treatment are conjugated to the gene transporter and a pharmaceutical composition for gene therapy including the complex as an active ingredient. In addition, the present invention relates to the gene transporter, gene delivery complex, and gene therapy using the gene transporter and gene delivery complex. It was confirmed that the PdXYP of the present invention has a considerably higher nucleic acid delivery rate than existing gene transporters, has almost no cytotoxicity in the conjugate when conjugated with DNA, also has very high in vivo transfection efficiency, and above all, especially has considerably high transfection efficiency for brain tissues, which has involved difficulty in gene therapy due to the blood brain barrier for a while.

Abstract: The present invention relates to a biodegradable polysorbitol-based osmotically active transporter (PSOAT) and gene therapy using the same as a gene carrier. The biodegradable polysorbitol-based osmotically active transporter (PSOAT) of the present invention includes a sorbitol skeleton, which imparts an osmotic pressure to the cell membrane to improve membrane permeability, thereby exhibiting remarkably improved transfection efficiency. Further, the polysorbitol-based osmotically active transporter of the present invention exhibits high DNA binding ability, effectively protects DNA from nuclease, exhibits physicochemical properties suitable for use as a gene carrier, and has very low cytotoxicity in vitro and in vivo, thereby capable of being used as a gene carrier for gene therapy.

Abstract: Disclosed herein are improved articles for screening candidate insect pest-repellents; and their uses in host-free methods and/or systems for screening candidate insect pest-repellents.

Abstract: The present invention relates to a magnetic resonance imaging (MRI) contrast agent coated with carboxylated mannan, particularly a carboxylated mannan coated superparamagnetic MRI contrast agent specifically targeting antigen presenting cells and having excellent in vivo stability, and a method for producing the same. The MRI contrast agent coated with carboxylated mannan of the present invention can provide excellent in vivo stability and biocompatibility owing to its high surface negative charge, and can be introduced specifically into antigen presenting cells owing to mannose of mannan, so as to visualize the antigen presenting cells and the tissue containing the antigen presenting cells in MRI.

Abstract: The present invention relates to a biodegradable polysorbitol-based osmotically active transporter (PSOAT) and gene therapy using the same as a gene carrier. The biodegradable polysorbitol-based osmotically active transporter (PSOAT) of the present invention includes a sorbitol skeleton, which imparts an osmotic pressure to the cell membrane to improve membrane permeability, thereby exhibiting remarkably improved transfection efficiency. Further, the polysorbitol-based osmotically active transporter of the present invention exhibits high DNA binding ability, effectively protects DNA from nuclease, exhibits physicochemical properties suitable for use as a gene carrier, and has very low cytotoxicity in vitro and in vivo, thereby capable of being used as a gene carrier for gene therapy.

Abstract: Disclosed herein are improved articles for screening candidate insect pest-repellents; and their uses in host-free methods and/or systems for screening candidate insect pest-repellents.

Abstract: The present invention uses the principles of electrochemical ion absorption (charging) and ion desorption (discharge), and relates to a continuous flow-electrode system, a high-capacity energy storage system, and a water treatment method using the same, in which high-capacity electric energy is stored as electrode materials of a slurry phase and electrolytes simultaneously flow in a successive manner within a fine flow channel structure formed on an electrode. More specifically, the present invention relates to a continuous flow-electrode system, an energy storage system, and a water treatment method, wherein electrode active materials consecutively flow in a slurry state whereby a high capacity is easily obtained without enlarging or stacking electrodes.