Abstract: Provided is a method for diagnosing and monitoring progression of cancer or effectiveness of a therapeutic treatment. The method includes detecting a methylation level of at least one gene in a biological sample containing circulating free DNA. Also provided are primer pairs and probes for diagnosis or prognosis of cancer in a subject in need thereof.

Abstract: The integrated circuit chip programming apparatus comprises a fixing device, an actuating device and a flexible device. The fixing device comprises a supporting part and a cover. One end of the cover is coupled with one end of the supporting part and comprises an accommodation space for accommodating a chip therein. The cover selectively covers or uncovers the supporting part so as to close or expose the accommodation space. The flexible device is coupled between the fixing device and the actuating device. When a force is against the forced end, the actuating device is rotated to drive the cover to expose the accommodation space. When no force is against the forced end or the force against the forced end is stopped, the flexible device provides a recovery force to allow the actuating device to rotate to drive the cover to close the accommodation space of the supporting part.

Abstract: The integrated circuit chip programming apparatus comprises a fixing device, an actuating device and a flexible device. The fixing device comprises a supporting part and a cover. One end of the cover is coupled with one end of the supporting part and comprises an accommodation space for accommodating a chip therein. The cover selectively covers or uncovers the supporting part so as to close or expose the accommodation space. The flexible device is coupled between the fixing device and the actuating device. When a force is against the forced end, the actuating device is rotated to drive the cover to expose the accommodation space. When no force is against the forced end or the force against the forced end is stopped, the flexible device provides a recovery force to allow the actuating device to rotate to drive the cover to close the accommodation space of the supporting part.

Abstract: The present invention discloses a method for extracting AIF and an application thereof to DCE-MRI. The method comprises steps: contacting a target tissue with a contrast agent to obtain a plurality of images; using the plurality of images to work out the tissue concentration curve of the contrast agent in each voxel; calculating the purity of the tissue concentration curve of each voxel according to the tissue concentration curves; and extracting the voxel having the highest purity as the optimized arterial location; and extracting the tissue concentration curve of the voxel having the highest purity as the arterial input function. The extracted AIF is applied to a pharmacokinetic model to obtain associated pharmacokinetic parameters. The present invention not only improves the accuracy and reliability of the derived quantitative indexes but also promotes the efficiency of the quantitative analysis.

Abstract: The present invention discloses a method for extracting AIF and an application thereof to DCE-MRI. The method comprises steps: contacting a target tissue with a contrast agent to obtain a plurality of images; using the plurality of images to work out the tissue concentration curve of the contrast agent in each voxel; calculating the purity of the tissue concentration curve of each voxel according to the tissue concentration curves; and extracting the voxel having the highest purity as the optimized arterial location; and extracting the tissue concentration curve of the voxel having the highest purity as the arterial input function. The extracted AIF is applied to a pharmacokinetic model to obtain associated pharmacokinetic parameters. The present invention not only improves the accuracy and reliability of the derived quantitative indexes but also promotes the efficiency of the quantitative analysis.

Abstract: Disclosed is an isolation-free in-circuit programming system including an in-circuit programmer and an application board connected to the in-circuit programmer through a peripheral interface bus and having a bus controller and a memory, wherein the bus controller is connected to the memory through a system bus, in which the in-circuit programmer includes a leakage current discharging circuit connected to the bus controller for detouring a leakage current flowing from the memory or the in-circuit programmer to the bus controller to flow therethrough. The in-circuit programmer also includes an input level shifter for receiving data signals from the memory and adjusting the high-level input voltage of the in-circuit programmer to decode any weak high-level output voltage from the memory, thereby allowing the high-level output voltage of the memory to be higher than the high-level input voltage of the in-circuit programmer.

Abstract: Disclosed is an isolation-free in-circuit programming system including an in-circuit programmer and an application board connected to the in-circuit programmer through a peripheral interface bus and having a bus controller and a memory, wherein the bus controller is connected to the memory through a system bus, in which the in-circuit programmer includes a leakage current discharging circuit connected to the bus controller for detouring a leakage current flowing from the memory or the in-circuit programmer to the bus controller to flow therethrough. The in-circuit programmer also includes an input level shifter for receiving data signals from the memory and adjusting the high-level input voltage of the in-circuit programmer to decode any weak high-level output voltage from the memory, thereby allowing the high-level output voltage of the memory to be higher than the high-level input voltage of the in-circuit programmer.

Abstract: A blind adaptive filtering method for receivers of communication systems without need of training sequences, and whose performance is close to that of the non-blind linear minimum mean square error (LMMSE) receivers with training sequences required in practical environments of finite signal-to-noise (SNR) and data length. This algorithm is an iterative batch processing algorithm using cumulant based inverse filter criteria with super-exponential convergence rate and low computational load. The receivers to which the presented algorithm can be applied are (but not limited to) equalizers of conventional time division multiple access (TDMA) digital communication systems, and smart antennas based on space-time processing for wireless communication systems.

Abstract: An apparatus, system, and method are disclosed for facilitating authenticated communication between authentication realms. The present invention includes an authentication gateway configured to authenticate a principal using a first authentication protocol. The first authentication protocol may be one of a variety of authentication protocols. A generator in communication with the authentication gateway generates a foreign realm authentication token that is compatible with a second authentication protocol and configured for inter-realm communication. A foreign realm authentication module then authenticates the principal to access services of a foreign realm using the foreign realm authentication token. The authentication is performed by the foreign realm authentication module in accordance with the second authentication protocol. The first authentication protocol may be a non-Kerberos protocol and the second authentication protocol may be a Kerberos protocol.

Abstract: A blind adaptive filtering method for receivers of communication systems without need of training sequences, and whose performance is close to that of the non-blind linear minimum mean square error (LMMSE) receivers with training sequences required in practical environments of finite signal-to-noise (SNR) and data length. This algorithm is an iterative batch processing algorithm using cumulant based inverse filter criteria with super-exponential convergence rate and low computational load. The receivers to which the presented algorithm can be applied are (but not limited to) equalizers of conventional time division multiple access (TDMA) digital communication systems, and smart antennas based on space-time processing for wireless communication systems.

Abstract: The present invention relates to a packing device for the receiving of the Christmas lamp string. It is to provide the Christmas lamp string after usage to be easily wound around the outer edges of connecting columns mainly by the positioning disks of both sides with the connecting columns binding together to achieve the purpose of receiving packing. Thus, it is very convenient to be taken out for usage next time. It is able to improve the disadvantage of hard to store the lamp string in the pass, and increase the practical effects.