Patents by Inventor Chongjun Liu

Chongjun Liu has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Crystal forms of azetidinone compounds and preparing methods thereof
    Patent number: 9802891
    Abstract: The present invention provides crystal forms of the compound of (3R,4S)-4-(4-hydroxyphenyl)-3-[3-(4-fluorophenyl)-4-hydroxybut-2(Z)-enyl]-1-(4-fluorophenyl)-2-azetidinone (formula A). The crystal forms can be characterized by X-ray powder diffraction (XRPD) spectra, differential scanning calorimetry (DSC) spectra, infrared absorption spectra and so on. Meanwhile, the present invention also provides methods for preparing the crystal forms of the compound of formula A, pharmaceutical compositions and uses thereof.
    Type: Grant
    Filed: December 21, 2016
    Date of Patent: October 31, 2017
    Assignee: Zhejiang Hisun Pharmaceutical Co., Ltd.
    Inventors: Hongyuan Wei, Chongjun Liu, Xuyang Zhao, Xiaojie Xu, Hua Bai, Yuncai Zhang
  • Crystal forms of azetidinone compounds and preparing methods thereof
    Patent number: 9776959
    Abstract: The present invention provides crystal forms of the compound of (3R,4S)-4-(4-hydroxyphenyl)-3-[3-(4-fluorophenyl)-4-hydroxybut-2(Z)-enyl]-1-(4-fluorophenyl)-2-azetidinone (formula A). The crystal forms can be characterized by X-ray powder diffraction (XRPD) spectra, differential scanning calorimetry (DSC) spectra, infrared absorption spectra and so on. Meanwhile, the present invention also provides methods for preparing the crystal forms of the compound of formula A, pharmaceutical compositions and uses thereof.
    Type: Grant
    Filed: December 21, 2016
    Date of Patent: October 3, 2017
    Assignee: Zhejiang Hisun Pharmaceutical Co., Ltd.
    Inventors: Hongyuan Wei, Chongjun Liu, Xuyang Zhao, Xiaojie Xu, Hua Bai, Yuncai Zhang
  • CRYSTAL FORMS OF AZETIDINONE COMPOUNDS AND PREPARING METHODS THEREOF
    Publication number: 20170114016
    Abstract: The present invention provides crystal forms of the compound of (3R,4S)-4-(4-hydroxyphenyl)-3-[3-(4-fluorophenyl)-4-hydroxybut-2(Z)-enyl]-1-(4-fluorophenyl)-2-azetidinone (formula A). The crystal forms can be characterized by X-ray powder diffraction (XRPD) spectra, differential scanning calorimetry (DSC) spectra, infrared absorption spectra and so on. Meanwhile, the present invention also provides methods for preparing the crystal forms of the compound of formula A, pharmaceutical compositions and uses thereof.
    Type: Application
    Filed: December 21, 2016
    Publication date: April 27, 2017
    Applicant: Zhejiang Hisun Pharmaceutical Co., Ltd.
    Inventors: Hongyuan Wei, Chongjun Liu, Xuyang Zhao, Xiaojie Xu, Hua Bai, Yuncai Zhang
  • CRYSTAL FORMS OF AZETIDINONE COMPOUNDS AND PREPARING METHODS THEREOF
    Publication number: 20170114015
    Abstract: The present invention provides crystal forms of the compound of (3R,4S)-4-(4-hydroxyphenyl)-3-[3-(4-fluorophenyl)-4-hydroxybut-2(Z)-enyl]-1-(4-fluorophenyl)-2-azetidinone (formula A). The crystal forms can be characterized by X-ray powder diffraction (XRPD) spectra, differential scanning calorimetry (DSC) spectra, infrared absorption spectra and so on. Meanwhile, the present invention also provides methods for preparing the crystal forms of the compound of formula A, pharmaceutical compositions and uses thereof.
    Type: Application
    Filed: December 21, 2016
    Publication date: April 27, 2017
    Applicant: Zhejiang Hisun Pharmaceutical Co., Ltd.
    Inventors: Hongyuan Wei, Chongjun Liu, Xuyang Zhao, Xiaojie Xu, Hua Bai, Yuncai Zhang
  • Crystal forms of azetidinone compounds and preparing methods thereof
    Patent number: 9567298
    Abstract: The present invention provides crystal forms of the compound of (3R,4S)-4-(4-hydroxyphenyl)-3-[3-(4-fluorophenyl)-4-hydroxybut-2(Z)-enyl]-1-(4-fluorophenyl)-2-azetidinone (formula A). The crystal forms can be characterized by X-ray powder diffraction (XRPD) spectra, differential scanning calorimetry (DSC) spectra, infrared absorption spectra and so on. Meanwhile, the present invention also provides methods for preparing the crystal forms of the compound of formula A, pharmaceutical compositions and uses thereof.
    Type: Grant
    Filed: September 5, 2013
    Date of Patent: February 14, 2017
    Assignee: Zhejiang Hisun Pharmaceutical Co., Ltd.
    Inventors: Hongyuan Wei, Chongjun Liu, Xuyang Zhao, Xiaojie Xu, Hua Bai, Yuncai Zhang
  • CRYSTAL FORMS OF AZETIDINONE COMPOUNDS AND PREPARING METHODS THEREOF
    Publication number: 20150218091
    Abstract: The present invention provides crystal forms of the compound of (3R,4S)-4-(4-hydroxyphenyl)-3-[3-(4-fluorophenyl)-4-hydroxybut-2(Z)-enyl]-1-(4-fluorophenyl)-2-azetidinone (formula A). The crystal forms can be characterized by X-ray powder diffraction (XRPD) spectra, differential scanning calorimetry (DSC) spectra, infrared absorption spectra and so on. Meanwhile, the present invention also provides methods for preparing the crystal forms of the compound of formula A, pharmaceutical compositions and uses thereof.
    Type: Application
    Filed: September 5, 2013
    Publication date: August 6, 2015
    Applicant: Zhejiang Hisun Pharmaceutical Co., Ltd.
    Inventors: Hongyuan Wei, Chongjun Liu, Xuyang Zhao, Xiaojie Xu, Hua Bai, Yuncai Zhang