Patents by Inventor Choon-Hwai Yap

Choon-Hwai Yap has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Patent number: 11808754
    Abstract: The systems and methods provided herein relate to the performance of inverse reconstruction algorithms from ultrasound radiofrequency data and stress-strain data. These systems and methods can be applied to any soft tissue mechanical measurements, providing information about both mechanical properties and fiber orientation, and the relationships between them.
    Type: Grant
    Filed: December 26, 2019
    Date of Patent: November 7, 2023
    Assignee: University of Pittsburgh—Of the Commonwealth System of Higher Education
    Inventors: Kang Kim, Choon Hwai Yap
  • Publication number: 20220339316
    Abstract: Described is a haemostatic device comprising a substrate and a surface formed on the substrate. The surface comprises at least one of micro- and nano-sized materials, the materials being partially embedded in a base, the surface substantially preventing wetting of the substrate. An embodiment of the device is carbon nano fibres embedded partially in a PDMS or PTFE base, on a substrate.
    Type: Application
    Filed: June 15, 2020
    Publication date: October 27, 2022
    Applicants: National University of Singapore, ETH Zurich
    Inventors: Choon Hwai YAP, Zhe LI, Dimosthenis POULIKAKOS, Athanasios MILIONIS
  • Publication number: 20200191766
    Abstract: The systems and methods provided herein relate to the performance of inverse reconstruction algorithms from ultrasound radiofrequency data and stress-strain data. These systems and methods can be applied to any soft tissue mechanical measurements, providing information about both mechanical properties and fiber orientation, and the relationships between them.
    Type: Application
    Filed: December 26, 2019
    Publication date: June 18, 2020
    Applicant: University of Pittsburgh - Of the Commonwealth System of Higher Education
    Inventors: Kang Kim, Choon Hwai Yap
  • Patent number: 10674993
    Abstract: An ultrasonic diagnostic imaging system is described which quantifies regurgitant flow through a mitral valve. A flow quantification processor (34) in the ultrasound system produces a mathematical model of a flow velocity field proximal to a regurgitant orifice. The velocity field model produces values of velocity vectors directed toward the regurgitant orifice. These modeled values are modified for the effects of ultrasound physics and ultrasound system operation to produce expected velocity values. The expected velocity values are compared with actual Doppler velocities measured by the ultrasound system, and the differences accumulated to a mean square error which is used to adjust parameters of the model such as the orifice location and flow velocities. When this iterative processing converges with a desired comparison, parameters derived from the finally adjusted model are used to calculate the true orifice location, flow rate, and volume flow.
    Type: Grant
    Filed: December 16, 2011
    Date of Patent: June 9, 2020
    Assignees: KONINKLIJKE PHILIPS N.V., GEORGIA TECH RESEARCH
    Inventors: Qifeng Wei, Karl Thiele, Ajit Yoganathan, Choon-Hwai Yap
  • Patent number: 10564143
    Abstract: The systems and methods provided herein relate to the performance of inverse reconstruction algorithms from ultrasound radiofrequency data and stress-strain data. These systems and methods can be applied to any soft tissue mechanical measurements, providing information about both mechanical properties and fiber orientation, and the relationships between them.
    Type: Grant
    Filed: March 6, 2014
    Date of Patent: February 18, 2020
    Assignee: University of Pittsburgh — Of the Commonwealth System of Higher Education
    Inventors: Kang Kim, Choon Hwai Yap
  • Patent number: 10463341
    Abstract: An ultrasonic diagnostic imaging system is described which quantifies regurgitant flow through a plurality of pinhole leaks or a slit leak of a mitral valve. A plurality of orifice locations of a leaking valve are identified and Doppler values obtained from a flow velocity field proximal each orifice. The Doppler values of each flow velocity field vectorially relating to the orifice location are processed to produce a measure of flow through the orifice. The flow measurements for a plurality of such orifices are summed to produce a quantified measure of regurgitant flow through a plurality of pinhole leaks or along a slit leak.
    Type: Grant
    Filed: December 15, 2011
    Date of Patent: November 5, 2019
    Assignees: Koninklijke Philips N.V., Georgia Tech Research
    Inventors: Qifeng Wei, Karl E. Thiele, Ajit P. Yoganathan, Choon-Hwai Yap
  • Patent number: 10231693
    Abstract: An ultrasonic diagnostic imaging system is described which quantifies regurgitant flow through a mitral valve, including the automatic indication of the location of a regurgitant orifice in an ultrasound image. A clinician images the regurgitant valve and indicates in the image the presumed location of the regurgitant orifice (130). A flow quantification processor is responsive to this initial location estimate by the clinician to calculate a refined estimation of the orifice location. The refined location is indicated on the ultrasound image by the imaging system, either by relocating an icon placed by the clinician, or displaying a second icon (132) on the image at the refined location.
    Type: Grant
    Filed: December 16, 2011
    Date of Patent: March 19, 2019
    Assignee: Koninklijke Philips N.V.
    Inventors: Qifeng Wei, Karl Erhard Thiele, Ajit Yoganathan, Choon-Hwai Yap
  • Publication number: 20130274606
    Abstract: An ultrasonic diagnostic imaging system is described which quantifies regurgitant flow through a mitral valve. A flow quantification processor (34) in the ultrasound system produces a mathematical model of a flow velocity field proximal to a regurgitant orifice. The velocity field model produces values of velocity vectors directed toward the regurgitant orifice. These modeled values are modified for the effects of ultrasound physics and ultrasound system operation to produce expected velocity values. The expected velocity values are compared with actual Doppler velocities measured by the ultrasound system, and the differences accumulated to a mean square error which is used to adjust parameters of the model such as the orifice location and flow velocities. When this iterative processing converges with a desired comparison, parameters derived from the finally adjusted model are used to calculate the true orifice location, flow rate, and volume flow.
    Type: Application
    Filed: December 16, 2011
    Publication date: October 17, 2013
    Applicant: KONINKLIJKE PHILIPS ELECTRONICS N.V.
    Inventors: Qifeng Wei, Karl Thiele, Ajit Yoganathan, Choon-Hwai Yap
  • Publication number: 20130261457
    Abstract: An ultrasonic diagnostic imaging system is described which quantifies regurgitant flow through a mitral valve, including the automatic indication of the location of a regurgitant orifice in an ultrasound image. A clinician images the regurgitant valve and indicates in the image the presumed location of the regurgitant orifice (130). A flow quantification processor is responsive to this initial location estimate by the clinician to calculate a refined estimation of the orifice location. The refined location is indicated on the ultrasound image by the imaging system, either by relocating an icon placed by the clinician, or displaying a second icon (132) on the image at the refined location.
    Type: Application
    Filed: December 16, 2011
    Publication date: October 3, 2013
    Applicant: KONINKLIJKE PHILIPS ELECTRONICS N.V.
    Inventors: Qifeng Wei, Karl Erhard Thiele, Ajit Yoganathan, Choon-Hwai Yap
  • Publication number: 20130261458
    Abstract: An ultrasonic diagnostic imaging system is described which quantifies regurgitant flow through a plurality of pinhole leaks or a slit leak of a mitral valve. A plurality of orifice locations of a leaking valve are identified and Doppler values obtained from a flow velocity field proximal each orifice. The Doppler values of each flow velocity field vectorially relating to the orifice location are processed to produce a measure of flow through the orifice. The flow measurements for a plurality of such orifices are summed to produce a quantified measure of regurgitant flow through a plurality of pinhole leaks or along a slit leak.
    Type: Application
    Filed: December 15, 2011
    Publication date: October 3, 2013
    Applicant: KONINKLIJKE PHILIPS ELECTRONICS N.V.
    Inventors: Qifeng Wei, Karl E. Thiele, Ajit P. Yoganathan, Choon-Hwai Yap