Patents by Inventor Choong-Min Ryu

Choong-Min Ryu has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Publication number: 20240148670
    Abstract: The present invention relates to an antimicrobial adjuvant containing a biphenyl derivative compound as an active ingredient, and a technology of various uses thereof. The compound of the present invention reduces the dosage of polymyxin antibiotics, which are administered to inhibit the proliferation of gram-negative bacteria, by enhancing the sensitivity of the gram-negative bacteria with respect to the polymyxin antibiotics, is concomitantly administered with the polymyxin antibiotics to show gram-negative bacteria growth inhibitory and killing effects, may notably reduce side effects such as nephrotoxicity, and may prevent or treat sepsis and septic shock due to antibiotic overuse.
    Type: Application
    Filed: January 28, 2022
    Publication date: May 9, 2024
    Applicant: KOREA RESEARCH INSTITUTE OF BIOSCIENCE AND BIOTECHNOLOGY
    Inventors: Jun-Seob KIM, Choong-Min RYU, Seon-Yeong KIM
  • Publication number: 20230292763
    Abstract: The present invention relates to four types of Gram-positive bacteria (Brevibacterium frigoritolerans (HRS1, KCTC 14301BP), Bacillus niacini (HRS2, KCTC 14302BP), Solibacillus silvestris (HRS3, KCTC 14303BP), and Bacillus luciferensis (HRS4, KCTC 14304BP) strains), which increase resistance of plants against plant pathogens and to a composition of a biocontrol agent by using same and, more specifically, to a microbial fertilizer having a control effect against microbial diseases such as bacterial wilt occurring in crops (tomatoes, peppers, etc.), and against pests such as aphids by using the strains alone or a mixture thereof.
    Type: Application
    Filed: March 8, 2023
    Publication date: September 21, 2023
    Inventors: Choong Min RYU, Sang Moo LEE
  • Patent number: 11051518
    Abstract: The present invention provides a strain of Pseudozyma churashimaensis RGJ1, which is isolated from a pepper plant and leads to induced systemic resistance against plant pathogens or plant viruses; a microbial preparation for controlling plant diseases or increasing plant yields, including, as an active ingredient, the strain or a culture thereof; a method for preparing the microbial preparation, including a step of culturing the strain; and a method for controlling plant diseases, including a step of performing dipping treatment, soil drenching treatment or spraying treatment onto aerial foliage for a plant seedling with the strain or the culture thereof.
    Type: Grant
    Filed: June 27, 2016
    Date of Patent: July 6, 2021
    Assignee: KOREA RESEARCH INSTITUTE OF BIOSCIENCE AND BIOTECHNOLOGY
    Inventors: Choong-Min Ryu, Ga-Hyung Lee
  • Publication number: 20200029574
    Abstract: The present invention provides a strain of Pseudozyma churashimaensis RGJ1, which is isolated from a pepper plant and leads to induced systemic resistance against plant pathogens or plant viruses; a microbial preparation for controlling plant diseases or increasing plant yields, including, as an active ingredient, the strain or a culture thereof; a method for preparing the microbial preparation, including a step of culturing the strain; and a method for controlling plant diseases, including a step of performing dipping treatment, soil drenching treatment or spraying treatment onto aerial foliage for a plant seedling with the strain or the culture thereof.
    Type: Application
    Filed: June 27, 2016
    Publication date: January 30, 2020
    Applicant: Korea Research Institute of Bioscience and Biotechnology
    Inventors: Choong-Min RYU, Ga-Hyung LEE
  • Patent number: 9781938
    Abstract: The present invention relates to a method of eliciting plant immune responses based on seed priming by using the heat (high temperature)-treated culture solution of Bacillus spp, and the high pressure-sterilized culture solution of Bacillus sp. strains PB69 and 1628 which have been selected in the present invention exhibits an activity of eliciting induced systemic resistance similar to BTH, and also has an effect for inducing promoted plant growth and controlling plant diseases, and thus it is expected to contribute to enhance the crop productivity.
    Type: Grant
    Filed: November 13, 2013
    Date of Patent: October 10, 2017
    Assignee: KOREA RESEARCH INSTITUTE OF BIOSCIENCE AND BIOTECHNOLOGY
    Inventors: Choong Min Ryu, Geun Cheol Song
  • Patent number: 9456608
    Abstract: The present invention relates to a recombinant vector containing a plant disease resistance-related 1B8-4-D7 gene from the soil metagenome, a host cell transformed with the recombinant vector, a recombinant protein produced by the transformed host cell, a plant disease resistance enhancer including the transformed host cell or the recombinant protein as an effective component, a method of enhancing resistance against plant pathogens including eliciting induced resistance by treating a plant with a composition including the transformed host cell or the recombinant protein, and a preparation for controlling plant disease including the transformed host cell or the recombinant protein.
    Type: Grant
    Filed: November 18, 2013
    Date of Patent: October 4, 2016
    Assignee: KOREA RESEARCH INSTITUTE OF BIOSCIENCE AND BIOTECHNOLOGY
    Inventors: Choong Min Ryu, Hyo Bee Park
  • Publication number: 20150289515
    Abstract: The present invention relates to a method of eliciting plant immune responses based on seed priming by using the heat (high temperature)-treated culture solution of Bacillus spp, and the high pressure-sterilized culture solution of Bacillus sp. strains PB69 and 1628 which have been selected in the present invention exhibits an activity of eliciting induced systemic resistance similar to BTH, and also has an effect for inducing promoted plant growth and controlling plant diseases, and thus it is expected to contribute to enhance the crop productivity.
    Type: Application
    Filed: November 13, 2013
    Publication date: October 15, 2015
    Inventors: Choong Min Ryu, Geun Cheol Song
  • Publication number: 20140140960
    Abstract: The present invention relates to a recombinant vector containing a plant disease resistance-related 1B8-4-D7 gene from the soil metagenome, a host cell transformed with the recombinant vector, a recombinant protein produced by the transformed host cell, a plant disease resistance enhancer including the transformed host cell or the recombinant protein as an effective component, a method of enhancing resistance against plant pathogens including eliciting induced resistance by treating a plant with a composition including the transformed host cell or the recombinant protein, and a preparation for controlling plant disease including the transformed host cell or the recombinant protein.
    Type: Application
    Filed: November 18, 2013
    Publication date: May 22, 2014
    Applicant: Korea Research Institute of Bioscience and Biotechnology
    Inventors: Choong Min RYU, Hyo Bee PARK
  • Publication number: 20130267422
    Abstract: The present invention relates to a composition for controlling plant disease comprising 3-pentanol as an effective component, a method of controlling plant disease including treating a plant with 3-pentanol for inducing induced systemic resistance, a formulation for controlling plant disease comprising the composition, a composition for controlling plant disease comprising, as an effective component, Bacillus amyloliquefaciens IN937a strain which produces 3-pentanol, and a method of controlling plant disease including treating a plant with the composition for inducing induced systemic resistance.
    Type: Application
    Filed: June 19, 2013
    Publication date: October 10, 2013
    Inventors: Choong Min RYU, Hwe Su Yi, Hye Kyung Choi
  • Patent number: 8329430
    Abstract: The present invention relates to a polymyxin synthetase isolated from Gram-positive Paenibacillus sp. and a gene cluster encoding the same, more precisely a polymyxin synthetase isolated from Paenibacillus polymyxa E681, ATCC21830 and F4 strains, a gene cluster encoding thereof and a preparation method of polymyxin or its derivatives using the gene cluster. The polymyxin synthetase of the present invention can be effectively used for the increase of productivity of polymyxin and the development of a novel antibiotic.
    Type: Grant
    Filed: March 19, 2010
    Date of Patent: December 11, 2012
    Assignee: Korea Research Institute of Bioscience and Biotechnology
    Inventors: Seung-Hwan Park, Jihyun F Kim, ChoongHwan Lee, Soo-Keun Choi, Heayoung Jeong, Seong-Bin Kim, Yon Kyoung Park, Rumi Kim, Choong-Min Ryu, Soo-Young Park
  • Publication number: 20100279347
    Abstract: The present invention relates to a polymyxin synthetase isolated from Gram-positive Paenibacillus sp. and a gene cluster encoding the same, more precisely a polymyxin synthetase isolated from Paenibacillus polymyxa E681, ATCC21830 and F4 strains, a gene cluster encoding thereof and a preparation method of polymyxin or its derivatives using the gene cluster. The polymyxin synthetase of the present invention can be effectively used for the increase of productivity of polymyxin and the development of a novel antibiotic.
    Type: Application
    Filed: March 19, 2010
    Publication date: November 4, 2010
    Applicant: Korea Research Institute of Bioscience and Biotechnology
    Inventors: Seung-Hwan Park, Jihyun F. Kim, ChoongHwan Lee, Soo-Keun Choi, Heayoung Jeong, Seong-Bin Kim, Yon Kyoung Park, Rumi Kim, Choong-Min Ryu, Soo-Young Park
  • Publication number: 20100281585
    Abstract: The present invention relates to a composition for increasing resistance to plant pathogen by inducing an immune reaction of a plant wherein said composition comprises bacterial genetic materials as an effective component, a method for increasing resistance to plant pathogen by inducing an immune reaction of a plant wherein said method comprises a step of treating the plant with bacterial genetic materials, a plant produced by mentioned method to have increased resistance to plant pathogen, and seeds of such plant.
    Type: Application
    Filed: November 23, 2007
    Publication date: November 4, 2010
    Applicant: KOREA RESEARCH INSTITUTE OF BIOSCIENCE AND BIOTECHNOLOGY
    Inventors: Choong Min Ryu, Bo Young Lee, Soo Hyun Lee
  • Patent number: 7811790
    Abstract: The present invention relates to a polymyxin synthetase isolated from Gram-positive Paenibacillus sp. and a gene cluster encoding the same, more precisely a polymyxin synthetase isolated from Paenibacillus polymyxa E681, a gene cluster encoding thereof and a preparation method of polymyxin or its derivatives using the gene cluster. The polymyxin synthetase of the present invention can be effectively used for the increase of productivity of polymyxin and the development of a novel antibiotic.
    Type: Grant
    Filed: November 8, 2006
    Date of Patent: October 12, 2010
    Assignee: Korea Research Institute of Bioscience and Biotechnology
    Inventors: Seung-Hwan Park, Jihyun F. Kim, ChoongHwan Lee, Soo-Keun Choi, Heayoung Jeong, Seong-Bin Kim, Yon Kyoung Park, Rumi Kim, Choong-Min Ryu, Soo-Young Park
  • Publication number: 20090226964
    Abstract: The present invention relates to a polymyxin synthetase isolated from Gram-positive Paenibacillus sp. and a gene cluster encoding the same, more precisely a polymyxin synthetase isolated from Paenibacillus polymyxa E681, a gene cluster encoding thereof and a preparation method of polymyxin or its derivatives using the gene cluster. The polymyxin synthetase of the present invention can be effectively used for the increase of productivity of polymyxin and the development of a novel antibiotic.
    Type: Application
    Filed: November 8, 2006
    Publication date: September 10, 2009
    Applicant: Korea Research Instituteof Bioscience and Biotechnology
    Inventors: Seung-Hwan Park, Jihyun F. Kim, ChoongHwan Lee, Soo-Keun Choi, Heayoung Jeong, Seong-Bin Kim, Yon Kyoung Park, Rumi Kim, Choong-Min Ryu, Soo-Young Park
  • Publication number: 20090138988
    Abstract: The invention provides methods of increasing resistance to disease in a plant. Also provided are plant steroid biosynthesis enzyme coding sequences, including sequences for squalene synthase, constructs comprising these sequences, plants transformed therewith and methods of use thereof. Methods for producing a plant with increased disease resistance are also provided. In certain aspects of the invention, methods for producing plants transformed with the nucleic acids are provided, the transformed plants exhibiting improved disease resistance.
    Type: Application
    Filed: July 21, 2008
    Publication date: May 28, 2009
    Inventors: Keri Wang, Choong-Min Ryu, Kirankumar Mysore
  • Patent number: 7476780
    Abstract: The invention provides novel methods and compositions for modulating gene function in plants. In particular, the invention provides methods and compositions that allow efficient induction of virus-induced gene silencing in plants. The invention is significant in that it allows high throughput analysis of gene function in plants.
    Type: Grant
    Filed: April 15, 2005
    Date of Patent: January 13, 2009
    Assignee: The Samuel Roberts Noble Foundation
    Inventors: Choong-Min Ryu, Kirankumar S. Mysore
  • Publication number: 20060037105
    Abstract: The invention provides novel methods and compositions for modulating gene function in plants. In particular, the invention provides methods and compositions that allow efficient induction of virus-induced gene silencing in plants. The invention is significant in that it allows high throughput analysis of gene function in plants.
    Type: Application
    Filed: April 15, 2005
    Publication date: February 16, 2006
    Inventors: Choong-Min Ryu, Kirankumar Mysore