Abstract: The present disclosure generally relates to approaches for improving water absorption and retention by the skin's surface. In particular, the disclosure provides compositions and methods for preparing mixtures comprised of ethoxylated oils and water or mixtures comprised of micro or nano emulsions and water, which provide enhanced skin hydration or moisturization to a subject.

Abstract: Aspects of the present invention are directed to compositions that are useful for delivery of an active ingredient to a subject. Some embodiments are formulated with an active ingredient, including, for example, a non-steroidal anti-inflammatory drug (NSAID), such as aspirin, ibuprofen, ketoprofen, or naproxen, acetaminophen, or a polypeptide or protein, such as insulin, wherein the active ingredient is stabilized and greater than 90% of the particles of the active ingredient have a particle size that is less than or equal to or any number in between 100, 90, 80, 70, 60, 50, 40, 30, 20, 19, 18, 17, 16, 15, 14, 13, 12, 11, 10, 9, 8, 7, 6, 5, or 4 nanometers, or smaller, as determined by Dynamic Light Scattering (DLS), using a volume-weighted particle size distribution calculation method.

Abstract: The present disclosure generally relates to approaches for improving water absorption and retention by the skin's surface. In particular, the disclosure provides compositions and methods for preparing mixtures comprised of ethoxylated oils and water or mixtures comprised of micro or nano emulsions and water, which provide enhanced skin hydration or moisturization to a subject.

Abstract: Aspects of the present invention are directed to compositions that are useful for delivery of an active ingredient to a subject. Some embodiments are formulated with an active ingredient, including, for example, a non-steroidal anti-inflammatory drug (NSAID), such as aspirin, ibuprofen, ketoprofen, or naproxen, acetaminophen, or a polypeptide or protein, such as insulin, wherein the active ingredient is stabilized and greater than 90% of the particles of the active ingredient have a particle size that is less than or equal to or any number in between 100, 90, 80, 70, 60, 50, 40, 30, 20, 19, 18, 17, 16, 15, 14, 13, 12, 11, 10, 9, 8, 7, 6, 5, or 4 nanometers, or smaller, as determined by Dynamic Light Scattering (DLS), using a volume-weighted particle size distribution calculation method.

Abstract: A system for monitoring the water level of a pressure drum having a pressure column comprises a plurality of electrodes communicating with the column for contacting water and steam within the column. Each electrode has its own location and produces a first output which corresponds to the presence of water or a second output which corresponds to the presence of steam. A discriminator is operatively connected to the electrodes; and the discriminator has an analog-to-digital converter for receiving the output of each electrode and converting the output to a digital signal which represents the water conductivity for each electrode. A central processor is operatively connected to the discriminator for powering the discriminator as well as for receiving the digital signals in order to determine a slope degradation between the conductivity and the location of each electrode in the column. The central processor also determines an inflection point between the water and the steam in the column.