Patents by Inventor Chris BAILEY-KELLOGG

Chris BAILEY-KELLOGG has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Deimmunized lysostaphin and methods of use
    Patent number: 12104186
    Abstract: Compositions comprising deimmunized lysostaphin and methods of using the same, e.g., to treat microbial infection in or on a subject, are provided.
    Type: Grant
    Filed: March 12, 2021
    Date of Patent: October 1, 2024
    Assignee: INSMED INCORPORATED
    Inventors: Karl E. Griswold, Chris Bailey-Kellogg, Yoonjoo Choi, Kristina Blazanovic, Hongliang Zhao, Deeptak Verma
  • Antibodies and methods of making same
    Patent number: 11649291
    Abstract: Provided are variants of a chimeric anti-EGFR antibody. In various embodiments, the variants exhibit substantially improved thermostabilities and/or substantially higher levels of humanness, while retaining binding affinity near the parental level. The consistently high quality of the turnkey CoDAH designs, over a whole panel of variants, suggests that a computationally-directed approach encapsulates key determinants of antibody structure and function.
    Type: Grant
    Filed: May 24, 2017
    Date of Patent: May 16, 2023
    Assignee: Insmed Incorporated
    Inventors: Karl Edwin Griswold, Chris Bailey-Kellogg, Yoonjoo Choi
  • IMMUNOLOGICALLY OPTIMIZED BOTULINUM TOXIN LIGHT CHAIN VARIANTS
    Publication number: 20230120677
    Abstract: Deimmunized botulinum toxin light chain (e.g., botulinum toxin serotype A light chains (BoNT/A-LC)) or fragments thereof are provided. Methods for treating or preventing diseases or disorders comprising administering to a subject a deimmunized botulinum toxin light chain (e.g., BoNT/A-LC) are provided.
    Type: Application
    Filed: January 20, 2021
    Publication date: April 20, 2023
    Inventors: Karl E. GRISWOLD, Chris BAILEY-KELLOGG, Yoonjoo CHOI, Yongliang FANG, Deeptak VERMA, Susan ESZTERHAS, Min DONG, Shin-Ichiro MIYASHITA
  • DEIMMUNIZED LYSOSTAPHIN AND METHODS OF USE
    Publication number: 20210395713
    Abstract: Compositions comprising deimmunized lysostaphin and methods of using the same, e.g., to treat microbial infection in or on a subject, are provided.
    Type: Application
    Filed: March 12, 2021
    Publication date: December 23, 2021
    Inventors: Karl E. GRISWOLD, Chris BAILEY-KELLOGG, Yoonjoo CHOI, Kristina BLAZANOVIC, Hongliang ZHAO, Deeptak Verma
  • Deimmunized lysostaphin and methods of use
    Patent number: 11091749
    Abstract: Compositions comprising deimmunized lysostaphin and methods of using the same, e.g., to treat microbial infection in or on a subject, are provided.
    Type: Grant
    Filed: June 5, 2019
    Date of Patent: August 17, 2021
    Assignees: TRUSTEES OF DARTMOUTH COLLEGE, STEALTH BIOLOGICS, LLC
    Inventors: Karl E. Griswold, Chris Bailey-Kellogg, Yoonjoo Choi, Kristina Blazanovic, Hongliang Zhao, Deeptak Verma
  • ANTIBODIES AND METHODS OF MAKING SAME
    Publication number: 20200317792
    Abstract: Provided are variants of a chimeric anti-EGFR antibody. In various embodiments, the variants exhibit substantially improved thermostabilities and/or substantially higher levels of humanness, while retaining binding affinity near the parental level. The consistently high quality of the turnkey CoDAH designs, over a whole panel of variants, suggests that a computationally-directed approach encapsulates key determinants of antibody structure and function.
    Type: Application
    Filed: May 24, 2017
    Publication date: October 8, 2020
    Inventors: Karl Edwin GRISWOLD, Chris BAILEY-KELLOGG, Yoonjoo CHOI
  • DEIMMUNIZED LYSOSTAPHIN AND METHODS OF USE
    Publication number: 20200040321
    Abstract: Compositions comprising deimmunized lysostaphin and methods of using the same, e.g., to treat microbial infection in or on a subject, are provided.
    Type: Application
    Filed: June 5, 2019
    Publication date: February 6, 2020
    Inventors: Karl E. GRISWOLD, Chris BAILEY-KELLOGG, Yoonjoo CHOI, Kristina BLAZANOVIC, Hongliang ZHAO, Deeptak Verma
  • Deimmunized lysostaphin and methods of use
    Patent number: 10358636
    Abstract: Compositions comprising deimmunized lysostaphin and methods of using the same, e.g., to treat microbial infection in or on a subject, are provided.
    Type: Grant
    Filed: May 14, 2015
    Date of Patent: July 23, 2019
    Assignees: STEALTH BIOLOGICS, LLC, TRUSTEES OF DARTMOUTH COLLEGE
    Inventors: Karl E. Griswold, Chris Bailey-Kellogg, Yoonjoo Choi, Kristina Blazanovic, Hongliang Zhao, Deeptak Verma
  • DEIMMUNIZED LYSOSTAPHIN AND METHODS OF USE
    Publication number: 20170145398
    Abstract: Compositions comprising deimmunized lysostaphin and methods of using the same, e.g., to treat microbial infection in or on a subject, are provided.
    Type: Application
    Filed: May 14, 2015
    Publication date: May 25, 2017
    Applicant: TRUSTEES OF DARTMOUTH COLLEGE
    Inventors: Karl E. GRISWOLD, Chris BAILEY-KELLOGG, Yoonjoo CHOI, Kristina BLAZANOVIC, Hongliang ZHAO