Abstract: Certain aspects of the present invention relate to modified hemoglobin proteins comprising at least one modification (e.g., at the thiol group of an exogenous amino acid residue) for homogenous conjugation of one or more polymeric moieties e.g. polyethylene glycol or derivatives thereof. Also included herein are methods of using such modified proteins and compositions comprising such proteins, e.g. in therapy.

Abstract: Certain aspects of the present invention relate to modified proteins e.g. oxygen-carrying proteins, comprising at least one modification for homogenous conjugation of one or more polymeric moieties e.g. polyethylene glycol or derivatives thereof.

Abstract: The present invention relates to modified proteins e.g. oxygen-carrying proteins, with improved or enhanced, in comparison to a reference protein, reduction of a metal ion associated with the modified protein. The present invention also relates to methods of using such modified proteins and compositions comprising such proteins e.g. in therapy.

Abstract: Water is prevented from entering the wall interior of a building from in and around a wall component, such as a window, mounted in the building wall, by positioning a diverter directly beneath the wall component. The diverter includes an upper surface that slopes toward the wall exterior, a plurality of spaced, parallel ribs extending upwardly from the upper surface and beyond the exterior wall to form a plurality of downwardly sloping channels, a cover over the outer ends of the ribs to form drainage openings at the ends of the channels. A downwardly extending non-linear pathway from the drainage openings to the exterior of the diverter prevents water from entering the wall interior through the channels.

Abstract: Water is prevented from entering the wall interior of a building from in and around a wall component, such as a window, mounted in the building wall, by positioning a diverter directly beneath the wall component. The diverter includes an upper surface that slopes toward the wall exterior, a plurality of spaced, parallel ribs extending upwardly from the upper surface and beyond the exterior wall to form a plurality of downwardly sloping channels, a cover over the outer ends of the ribs to form drainage openings at the ends of the channels, and filters in the channels to prevent water from entering the wall interior through the channels.