Patents by Inventor Chris Evelyn

Chris Evelyn has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • SOS1 ALLOSTERIC SITE TARGETING
    Publication number: 20210338694
    Abstract: Disclosed herein are small molecule SOS1 allosteric site inhibitors, pharmaceutical compositions, and methods of use thereof.
    Type: Application
    Filed: May 3, 2021
    Publication date: November 4, 2021
    Inventors: Yi Zheng, Chris Evelyn, William Seibel, Jaroslaw Meller, Jing Zhang
  • METHODS AND COMPOSITIONS FOR MODULATING RHO-MEDIATED GENE TRANSCRIPTION
    Publication number: 20120252792
    Abstract: The invention provides methods, compositions, and kits for the inhibition of members of the Rho GTPase family. Specifically, the invention provides methods, compositions and kits for the inhibition of RhoA and/or RhoC transcriptional signalling. The invention finds use in treatment of Rho-mediated disease states (e.g., tumor metastasis, inflammation, inflammatory disease), Rho-mediated biological conditions, and in cell signaling research.
    Type: Application
    Filed: September 17, 2010
    Publication date: October 4, 2012
    Applicant: THE REGENTS OF THE UNIVERSITY OF MICHIGAN
    Inventors: Richard Neubig, Chris Evelyn, Jenny Ryu, Scott Larsen, Jessica Bell
  • Methods and Compositions for Modulating RHO-Mediated Gene Transcription
    Publication number: 20090264533
    Abstract: The present invention is directed to methods and compositions methods and compositions for determining and inhibiting gene transcription in mammalian cells. The invention relates to novel inhibitors of rho-mediated gene transcription and to compounds that may be used as therapeutic agents.
    Type: Application
    Filed: March 21, 2006
    Publication date: October 22, 2009
    Inventors: Richard Neubig, Chris Evelyn