Patents by Inventor Chris Fleming

Chris Fleming has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • ACCURATE ENUMERATION OF LEUKOCYTE SUBSETS IN PERIPHERAL BLOOD WITH A 15-COLOR IMMUNOPROFILING PANEL USING A SPECTRAL FLOW CYTOMETER
    Publication number: 20250199002
    Abstract: In one embodiment, a method of building an optimized color flow cytometry panel is disclosed using a spectral flow cytometer with a least three excitation lasers and thirty-eight color detectors. In another embodiment, a graphical user interface is disclosed generated by a server computer from a fluorochrome database and displayed by a client computer to assist in the selection of a set of fluorochromes for use in an assay to analyze biological samples. The GUI can display spectra graphs to visually show how fluorochromes may overlap and can generate similarity indexes for the paired fluorochrome interference and a complexity index for overall many to many interferences generated by a selected group or set of fluorochromes.
    Type: Application
    Filed: December 13, 2023
    Publication date: June 19, 2025
    Inventors: Yoshinori Fukazawa, Mark Edinger, Ivette Amador, Chris Fleming, Jun Deng, Alice Wang
  • T-structure invasive cleavage assays, consistent nucleic acid dispensing, and low level target nucleic acid detection
    Patent number: 8354232
    Abstract: The present invention relates to systems, methods and kits for low-level detection of nucleic acids, detecting at least two different viral sequences in a single reaction vessel, and increasing the dynamic range of detection of a viral target nucleic acid in a sample. The present invention also relates to T-structure invasive cleavage assays, as well as T-structure related target dependent non-target amplification methods and compositions. The present invention further relates to methods, compositions, devices and systems for consistent nucleic acid dispensing onto surfaces.
    Type: Grant
    Filed: July 20, 2010
    Date of Patent: January 15, 2013
    Assignee: Third Wave Technologies, Inc.
    Inventors: Hatim Taysir Allawi, Vecheslav A. Elagin, Victor I. Lyamichev, Kwok Wu, Walter Iszczyszyn, Chris Fleming, LuAnne Chehak, Scott M. Law
  • T-STRUCTURE INVASIVE CLEAVAGE ASSAYS, CONSISTENT NUCLEIC ACID DISPENSING, AND LOW LEVEL TARGET NUCLEIC ACID DETECTION
    Publication number: 20100285488
    Abstract: The present invention relates to systems, methods and kits for low-level detection of nucleic acids, detecting at least two different viral sequences in a single reaction vessel, and increasing the dynamic range of detection of a viral target nucleic acid in a sample. The present invention also relates to T-structure invasive cleavage assays, as well as T-structure related target dependent non-target amplification methods and compositions. The present invention further relates to methods, compositions, devices and systems for consistent nucleic acid dispensing onto surfaces.
    Type: Application
    Filed: July 20, 2010
    Publication date: November 11, 2010
    Applicant: THIRD WAVE TECHNOLOGIES, INC.
    Inventors: Hatim Taysir Allawi, Vecheslav A. Elagin, Victor A. Lyamichev, Kwok Wu, Walter Iszczyszyn, Chris Fleming, LuAnne Chehak, Scott M. Law
  • RECYCLING OF SOLIDS IN OXIDATIVE PRESSURE LEACHING OF METALS USING HALIDE IONS
    Publication number: 20100206135
    Abstract: The invention provides a recycling step in an oxidative pressure leaching process for recovery of metals using halide ions, in which a portion of the leached solids are recycled back to the feed to the autoclave, to allow two or more passes through the high temperature leaching step.
    Type: Application
    Filed: May 11, 2007
    Publication date: August 19, 2010
    Applicant: International PGM Technologies
    Inventors: David Dreisinger, Chris Fleming
  • T-structure invasive cleavage assays, consistent nucleic acid dispensing, and low level target nucleic acid detection
    Patent number: 7759062
    Abstract: The present invention relates to systems, methods and kits for low-level detection of nucleic acids, detecting at least two different viral sequences in a single reaction vessel, and increasing the dynamic range of detection of a viral target nucleic acid in a sample. The present invention also relates to T-structure invasive cleavage assays, as well as T-structure related target dependent non-target amplification methods and compositions. The present invention further relates to methods, compositions, devices and systems for consistent nucleic acid dispensing onto surfaces.
    Type: Grant
    Filed: June 11, 2007
    Date of Patent: July 20, 2010
    Assignee: Third Wave Technologies, Inc.
    Inventors: Hatim Taysir Allawi, Vecheslav A. Elagin, Victor A. Lyamichev, Kwok Wu, Walter Iszczyszyn, Chris Fleming, LuAnne Chehak, Scott M. Law
  • T-structure invasive cleavage assays, consistent nucleic acid dispensing, and low level target nucleic acid detection
    Publication number: 20080131870
    Abstract: The present invention relates to systems, methods and kits for low-level detection of nucleic acids, detecting at least two different viral sequences in a single reaction vessel, and increasing the dynamic range of detection of a viral target nucleic acid in a sample. The present invention also relates to T-structure invasive cleavage assays, as well as T-structure related target dependent non-target amplification methods and compositions. The present invention further relates to methods, compositions, devices and systems for consistent nucleic acid dispensing onto surfaces.
    Type: Application
    Filed: June 11, 2007
    Publication date: June 5, 2008
    Applicant: Third Wave Technologies, Inc.
    Inventors: Hatim Taysir Allawi, Vecheslav A. Elagin, Victor A. Lyamichev, Kwok Wu, Walter Iszczyszyn, Chris Fleming, LuAnne Chehak, Scott M. Law