Abstract: Systems and methods are provided for use in applying treatments to crops in fields. One example computer-implemented method includes determining a growth stage vector indicative of a growth stage of a crop in a field, using a GRU-based phenology model, based on a planting date of the crop and weather data for the field. The method also includes determining a disease risk for the crop in the field based on a disease risk model and the growth stage vector, determining a residual protection of the field for a prior treatment of the field, and determining whether application of the treatment is recommended for the field based on the disease risk and the determined residual protection. The method then includes, in response to determining that application of the treatment is recommended, identifying application intervals for the treatment based on the weather data for the application intervals.

Abstract: Disclosed herein are methods that have been developed to control the formation of disulfide bonds between polypeptides of a multimeric protein produced by a bioprocess. Also disclosed are protein solution parameters that allow for controlling the formation of disulfide bonds. In one example, the methods disclosed herein can be used to control the proportion of half antibody molecules in an antibody solution.

Abstract: Disclosed herein are methods that have been developed to control the formation of disulfide bonds between polypeptides of a multimeric protein produced by a bioprocess. Also disclosed are protein solution parameters that allow for controlling the formation of disulfide bonds. In one example, the methods disclosed herein can be used to control the proportion of half antibody molecules in an antibody solution.

Abstract: Disclosed herein are methods that have been developed to control the formation of disulfide bonds between polypeptides of a multimeric protein produced by a bioprocess. Also disclosed are protein solution parameters that allow for controlling the formation of disulfide bonds. In one example, the methods disclosed herein can be used to control the proportion of half antibody molecules in an antibody solution.

Abstract: Disclosed herein are methods that have been developed to control the formation of disulfide bonds between polypeptides of a multimeric protein produced by a bioprocess. Also disclosed are protein solution parameters that allow for controlling the formation of disulfide bonds. In one example, the methods disclosed herein can be used to control the proportion of half antibody molecules in an antibody solution.