Patents by Inventor Chris Janetopoulos

Chris Janetopoulos has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Photolithographed micro-mirror well for 3D tomogram imaging of individual cells
    Patent number: 8339704
    Abstract: A micro-mirror well. In one embodiment the micro-mirror well includes a plurality of planar mirrors arranged around an axis of symmetry and inclined to form a pyramid well, where each of the plurality of planar mirrors is capable of reflecting light emitting from an object of interest placed inside the pyramid well.
    Type: Grant
    Filed: May 20, 2011
    Date of Patent: December 25, 2012
    Assignee: Vanderbilt University
    Inventors: Kevin T. Seale, Ronald S. Reiserer, John P. Wikswo, Sandra Rosenthal, Jeffrey Chamberlain, Charles Wright, Dmitry Markov, Chris Janetopoulos
  • BOTTOMLESS MICRO-MIRROR WELL FOR 3D IMAGING FOR AN OBJECT OF INTEREST
    Publication number: 20110058252
    Abstract: A bottomless micro-mirror well. In one embodiment, the bottomless micro-mirror well includes a substrate having a first surface and an opposite, second surface defining a body portion between the first surface and the opposite, second surface, where the body portion defines an inverted pyramidal well having at least three side surfaces extending to each other and defining an opening between a first sidewall and a second sidewall of the body portion, and where each of the at least three side surfaces is configured to reflect light emitting from an object of interest.
    Type: Application
    Filed: May 26, 2010
    Publication date: March 10, 2011
    Applicant: VANDERBILT UNIVERSITY
    Inventors: Chris Janetopoulos, Dmitry Markov, Ronald S. Reiserer, Kevin T. Seale, John P. Wikswo, Charles Wright
  • Heterotrimeric G-protein
    Patent number: 7691564
    Abstract: Receptor mediated activation of heterotrimeric G-proteins is visualized in living cells by monitoring fluorescence resonance energy transfer (FRET) between subunits of a G protein fused to cyan and yellow fluorescent proteins. The G-protein heterotrimer rapidly dissociates and reassociates upon addition and removal of cognate ligand. Energy transfer pairs of G-proteins enables direct in situ detection and have applications for drug screening and GPCR de-orphaning.
    Type: Grant
    Filed: January 3, 2006
    Date of Patent: April 6, 2010
    Assignee: The Johns Hopkins University
    Inventors: Peter N. Devreotes, Chris Janetopoulos
  • Heterotrimeric G-protein
    Publication number: 20060223115
    Abstract: Receptor mediated activation of heterotrimeric G-proteins is visualized in living cells by monitoring fluorescence resonance energy transfer (FRET) between subunits of a G protein fused to cyan and yellow fluorescent proteins. The G-protein heterotrimer rapidly dissociates and reassociates upon addition and removal of cognate ligand. Energy transfer pairs of G-proteins enables direct in situ detection and have applications for drug screening and GPCR de-orphaning.
    Type: Application
    Filed: January 3, 2006
    Publication date: October 5, 2006
    Applicant: The Johns Hopkins University
    Inventors: Peter Devreotes, Chris Janetopoulos
  • Receptor mediated activation of heterotrimeric G-proteins
    Publication number: 20020048811
    Abstract: Receptor mediated activation of heterotrimeric G-proteins is visualized in living cells by monitoring fluorescence resonance energy transfer (FRET) between subunits of a G protein fused to cyan and yellow fluorescent proteins. The G-protein heterotrimer rapidly dissociates and reassociates upon addition and removal of cognate ligand. Energy transfer pairs of G-proteins enables direct in situ detection and have applications for drug screening and GPCR de-orphaning.
    Type: Application
    Filed: January 19, 2001
    Publication date: April 25, 2002
    Inventors: Peter N. Devreotes, Chris Janetopoulos