Abstract: A pipeline inspection apparatus includes a main body. A sealing structure attached to the main body seals against an internal surface of the pipeline. An imaging module includes a camera and a light source. The light source is arranged to emit light in a direction towards the internal surface of the pipeline. The camera is arranged such that, in use, the camera captures image data of the internal surface of the pipeline. Control circuitry includes a power supply and memory for storing data captured by said camera, wherein the sealing structure forms a seal against the internal surface of the pipeline such that, in use, a fluid flowing along the pipeline applies a driving force to the pipeline inspection apparatus to propel the apparatus along the pipeline.

Abstract: A pipeline inspection apparatus includes a main body. A sealing structure attached to the main body seals against an internal surface of the pipeline. An imaging module includes a camera and a light source. The light source is arranged to emit light in a direction towards the internal surface of the pipeline. The camera is arranged such that, in use, the camera captures image data of the internal surface of the pipeline. Control circuitry includes a power supply and memory for storing data captured by said camera, wherein the sealing structure forms a seal against the internal surface of the pipeline such that, in use, a fluid flowing along the pipeline applies a driving force to the pipeline inspection apparatus to propel the apparatus along the pipeline.

Abstract: According to certain embodiments of the present invention, methods for modulating the production of sialic acid in a system are provided, which comprise providing the system with a wild-type GNE-encoding nucleic acid sequence. According to such embodiments, the system may comprise a cell, muscular tissue, or other desirable targets. Similarly, the present invention encompasses methods for producing wild-type GNE in a system that comprises a mutated endogenous GNE-encoding sequence. In other words, the present invention includes providing, for example, a cell or muscular tissue that harbors a mutated (defective) GNE-encoding sequence with a functional wild-type GNE encoding sequence.

Abstract: This invention relates to a pipeline inspection apparatus and to a method of inspecting the internal surfaces of a pipeline using a pipeline inspection apparatus.

Abstract: According to certain embodiments of the present invention, methods for modulating the production of sialic acid in a system are provided, which comprise providing the system with a wild-type GNE-encoding nucleic acid sequence. According to such embodiments, the system may comprise a cell, muscular tissue, or other desirable targets. Similarly, the present invention encompasses methods for producing wild-type GNE in a system that comprises a mutated endogenous GNE-encoding sequence. In other words, the present invention includes providing, for example, a cell or muscular tissue that harbors a mutated (defective) GNE-encoding sequence with a functional wild-type GNE encoding sequence.