Patents by Inventor Chris Leidel

Chris Leidel has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Therapeutic cell washing, concentration, and separation utilizing acoustophoresis
    Patent number: 10640760
    Abstract: Multi-stage acoustophoretic devices for continuously separating a second fluid or a particulate from a host fluid are disclosed. Methods of operating the multi-stage acoustophoretic devices are also disclosed. The systems may include multiple acoustophoretic devices fluidly connected to one another in series, each acoustophoretic device comprising a flow chamber, an ultrasonic transducer capable of creating a multi-dimensional acoustic standing wave, and a reflector. The systems can further include pumps and flowmeters.
    Type: Grant
    Filed: May 3, 2017
    Date of Patent: May 5, 2020
    Assignee: FloDesign Sonics, Inc.
    Inventors: Bart Lipkens, Walter M. Presz, Jr., Brian Dutra, Rudolf Gilmanshin, Jason Dionne, Chris Leidel, Louis Masi, Goutam Ghoshal, Kedar Chitale
  • THERAPEUTIC CELL WASHING, CONCENTRATION, AND SEPARATION UTILIZING ACOUSTOPHORESIS
    Publication number: 20170321208
    Abstract: Multi-stage acoustophoretic devices for continuously separating a second fluid or a particulate from a host fluid are disclosed. Methods of operating the multi-stage acoustophoretic devices are also disclosed. The systems may include multiple acoustophoretic devices fluidly connected to one another in series, each acoustophoretic device comprising a flow chamber, an ultrasonic transducer capable of creating a multi-dimensional acoustic standing wave, and a reflector. The systems can further include pumps and flowmeters.
    Type: Application
    Filed: May 3, 2017
    Publication date: November 9, 2017
    Inventors: Bart Lipkens, Walter M. Presz, JR., Brian Dutra, Rudolf Gilmanshin, Jason Dionne, Chris Leidel, Louis Masi, Goutam Ghoshal
  • Acoustic bioreactor processes
    Patent number: 9688958
    Abstract: A series of multi-dimensional acoustic standing waves is set up inside a growth volume of a bioreactor. The acoustic standing waves are used to hold a cell culture in place as a nutrient fluid stream flows through the cell culture. The nutrient fluid stream dislodges some cells from the cell culture, which can then be recovered for cell therapy applications. The cell culture continues to expand and reproduce, permitting continuous recovery of cells from the bioreactor.
    Type: Grant
    Filed: August 23, 2016
    Date of Patent: June 27, 2017
    Assignee: FLODESIGN SONICS, INC.
    Inventors: Thomas J. Kennedy, III, Bart Lipkens, Louis Masi, Stanley Kowalski, Chris Leidel
  • ACOUSTIC BIOREACTOR PROCESSES
    Publication number: 20160369236
    Abstract: A series of multi-dimensional acoustic standing waves is set up inside a growth volume of a bioreactor. The acoustic standing waves are used to hold a cell culture in place as a nutrient fluid stream flows through the cell culture. The nutrient fluid stream dislodges some cells from the cell culture, which can then be recovered for cell therapy applications. The cell culture continues to expand and reproduce, permitting continuous recovery of cells from the bioreactor.
    Type: Application
    Filed: August 23, 2016
    Publication date: December 22, 2016
    Applicant: FloDesign Sonics, Inc.
    Inventors: Thomas J. Kennedy, III, Bart Lipkens, Louis Masi, Stanley Kowalski, Chris Leidel
  • Acoustic bioreactor processes
    Patent number: 9422328
    Abstract: A series of multi-dimensional acoustic standing waves is set up inside a growth volume of a bioreactor. The acoustic standing waves are used to hold a cell culture in place as a nutrient fluid stream flows through the cell culture. Biomolecules produced by the cell culture are collected by the nutrient fluid stream and separated downstream of the cell culture.
    Type: Grant
    Filed: July 11, 2014
    Date of Patent: August 23, 2016
    Assignee: FloDesign Sonics, Inc.
    Inventors: Thomas J. Kennedy, III, Bart Lipkens, Louis Masi, Stanley Kowalski, III, Chris Leidel
  • ACOUSTIC BIOREACTOR PROCESSES
    Publication number: 20140329997
    Abstract: A series of multi-dimensional acoustic standing waves is set up inside a growth volume of a bioreactor. The acoustic standing waves are used to hold a cell culture in place as a nutrient fluid stream flows through the cell culture. Biomolecules produced by the cell culture are collected by the nutrient fluid stream and separated downstream of the cell culture.
    Type: Application
    Filed: July 11, 2014
    Publication date: November 6, 2014
    Inventors: Thomas J. Kennedy, III, Bart Lipkens, Louis Masi, Stanley Kowalski, III, Chris Leidel