Patents by Inventor Chris McMaster

Chris McMaster has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Treatment of parkinson's disease through ARFGAP1 inhibition
    Patent number: 10300055
    Abstract: Methods are provided for the treatment of Parkinson's disease (PD) in patients bearing mutations in the LRRK2 gene. A therapeutically effective amount of piperazine derivative compounds are employed to inhibit the biological activity of ArfGAP1, inhibition that counteracts the deleterious effects of mutations in, or increased expression of, the LRRK2 protein.
    Type: Grant
    Filed: April 10, 2015
    Date of Patent: May 28, 2019
    Assignee: DALHOUSIE UNIVERSITY
    Inventors: Michel Roberge, Chris McMaster, Carla Zimmerman, Pak Poon
  • TREATMENT OF PARKINSON'S DISEASE THROUGH ARFGAP1 INHIBITION USING SUBSTITUTED PIPERAZINE DERIVATIVES
    Publication number: 20170020866
    Abstract: Methods are provided for the treatment of Parkinson's disease (PD) in patients bearing mutations in the LRRK2 gene. A therapeutically effective amount of piperazine derivative compounds are employed to inhibit the biological activity of ArfGAP1, inhibition that counteracts the deleterious effects of mutations in, or increased expression of, the LRRK2 protein.
    Type: Application
    Filed: April 10, 2015
    Publication date: January 26, 2017
    Inventors: Michel Roberge, Chris McMaster, Carla Zimmerman, Pak Poon