Abstract: The present disclosure provides methods for assessing likelihood of development of HIV-associated neurocognitive disorder (HAND) in a HIV patient. Also provided herein are methods for treating a HIV patient, such as, a HIV patient with increased level of a mi RNA that downregulates a peroxin and/or decreased level of a peroxisomal activity biomarker and/or increased level of a substrate of a peroxisomal enzyme. The present disclosure also provides methods for monitoring efficacy of a treatment regimen for a HIV patient.

Abstract: Methods and apparatus for performing an osteotomy. One embodiment includes a kit comprising a bone plate, a bridging device, and a spreading device. The bridge is configured to hold open the incision in the bone, whether the spreading device is inserted into the bone, or the bone plate is attached to the bone. The spreading device preferably includes a scissors-type mechanism for spreading two wedge-shaped members apart, contemplating both pivotal and displacement movements of one wedging member relative to another wedging member. The spring device preferably includes an ergonomic grip for the hand of the physician, and a hammering surface useful in inserting the spreading device into the incision.

Abstract: Methods and apparatus for performing an osteotomy. One embodiment includes a kit comprising a bone plate, a bridging device, and a spreading device. The bridge is configured to hold open the incision in the bone, whether the spreading device is inserted into the bone, or the bone plate is attached to the bone. The spreading device preferably includes a scissors-type mechanism for spreading two wedge-shaped members apart, contemplating both pivotal and displacement movements of one wedging member relative to another wedging member. The spring device preferably includes an ergonomic grip for the hand of the physician, and a hammering surface useful in inserting the spreading device into the incision.

Abstract: The present disclosure provides methods for assessing likelihood of development of HIV-associated neurocognitive disorder (HAND) in a HIV patient. Also provided herein are methods for treating a HIV patient, such as, a HIV patient with increased level of a mi RNA that downregulates a peroxin and/or decreased level of a peroxisomal activity biomarker and/or increased level of a substrate of a peroxisomal enzyme. The present disclosure also provides methods for monitoring efficacy of a treatment regimen for a HIV patient.

Abstract: Methods and apparatus for performing an osteotomy. One embodiment includes a kit comprising a bone plate, a bridging device, and a spreading device. The bridge is configured to hold open the incision in the bone, whether the spreading device is inserted into the bone, or the bone plate is attached to the bone. The spreading device preferably includes a scissors-type mechanism for spreading two wedge-shaped members apart, contemplating both pivotal and displacement movements of one wedging member relative to another wedging member. The spring device preferably includes an ergonomic grip for the hand of the physician, and a hammering surface useful in inserting the spreading device into the incision.

Abstract: Ultra fine and nanometer powders and a method of producing same are provided, preferably refractory metal and ceramic nanopowders. When certain precursors are injected into the plasma flame in a reactor chamber, the materials are heated, melted and vaporized and the chemical reaction is induced in the vapor phase. The vapor phase is quenched rapidly to solid phase to yield the ultra pure, ultra fine and nano product. With this technique, powders have been made 20 nanometers in size in a system capable of a bulk production rate of more than 10 lbs/hr. The process is particularly applicable to tungsten, molybdenum, rhenium, tungsten carbide, molybdenum carbide and other related materials.

Abstract: Ultra fine and nanometer powders and a method of producing same are provided, preferably refractory metal and ceramic nanopowders. When certain precursors are injected into the plasma flame in a reactor chamber, the materials are heated, melted and vaporized and the chemical reaction is induced in the vapor phase. The vapor phase is quenched rapidly to solid phase to yield the ultra pure, ultra fine and nano product. With this technique, powders have been made 20 nanometers in size in a system capable of a bulk production rate of more than 10 lbs/hr. The process is particularly applicable to tungsten, molybdenum, rhenium, tungsten carbide, molybdenum carbide and other related materials.

Abstract: Methods may include detecting whether a data message alert is stored in a dedicated alert field within a memory of the medical device upon interrogating the medical device with a programmer. The methods may also include communicating the data message alert via the programmer in response to detecting the data message alert stored in the dedicated alert field. A system may include a programmer, a medical device, and a link between the programmer and the medical device. The programmer is operative to provide, detect, and communicate a data message alert stored on the medical device in a dedicated alert field. The dedicated alert field is a free form data field having the capability to store the data message alert in any data format. The programmer is also operative to communicate the data message alert in any data format in which the data message alert is stored.

Abstract: A high temperature and highly corrosive resistant structure and method of fabricating the structure. In one embodiment of the present invention, vacuum plasma spray or other materials deposition techniques are used to fabricate the structure on a removable support member in the form of a gradient or composite structure that sequentially consists of a 100% ceramic interior layer, a first transition layer of ceramic/refractory metal, a layer of 100% refractory metal, a second transition layer of ceramic/refractory metal, and an outer layer of 100% ceramic material. In a second embodiment, the ceramic/refractory metal/ceramic cartridge is formed without transition layers between the ceramic and metal layers. In another embodiment of the invention the structure is fabricated on a removable support member by depositing an outer layer of ceramic material on a refractory metal. No transition layers of ceramic material/refractory metals are used.

Abstract: A high temperature and highly corrosive resistant structure and method of fabricating the structure. In one embodiment of the present invention, vacuum plasma spray or other materials deposition techniques are used to fabricate the structure on a removable support member in the form of a gradient or composite structure that sequentially consists of a 100% ceramic interior layer, a first transition layer of ceramic/refractory metal, a layer of 100% refractory metal, a second transition layer of ceramic/refractory metal, and an outer layer of 100% ceramic material. In a second embodiment, the ceramic/refractory metal/ceramic cartridge is formed without transition layers between the ceramic and metal layers. In another embodiment of the invention the structure is fabricated on a removable support member by depositing an outer layer of ceramic material on a refractory metal. No transition layers of ceramic material/refractory metals are used.