Patents by Inventor Chris REHSE

Chris REHSE has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Patent number: 11999966
    Abstract: Nanostraws and to methods of utilizing them in order to deliver biologically relevant molecules such as DNA, RNA, proteins etc., into non-adherent cells such as immune cells, embryos, plant cells, bacteria, yeast etc. The methods described herein are repeatedly capable of delivering biologically relevant cargo into non-adherent cells, with high cell viability, dosage control, unaffected proliferation or cellular development, and with high efficiency. Among other uses, these new delivery methods will allow to scale pre-clinical cell reprogramming techniques to clinical applications.
    Type: Grant
    Filed: October 27, 2020
    Date of Patent: June 4, 2024
    Assignee: The Board of Trustees of the Leland Stanford Junior University
    Inventors: Karl Martin Hjort, Sergio Leal-Ortiz, Yuhong Cao, Chris Rehse, Andy Kah Ping Tay, Nicholas A. Melosh
  • Patent number: 11344249
    Abstract: The invention relates to a device for neurovascular stimulation, at least comprising: at least one brain activity sensor, at least one cardiovascular sensor, at least one computing unit and at least one output unit. The computing unit comprises at least one task algorithm, wherein signals of at least the brain activity sensor and the cardiovascular sensor can be received by the computing unit, and wherein a task, which is in correlation with at least the signals from at least the brain activity sensor and the signals of the cardiovascular sensor, can be determined by means of the task algorithm and can be output by means of the output unit.
    Type: Grant
    Filed: December 13, 2016
    Date of Patent: May 31, 2022
    Assignee: NEOTIV GMBH
    Inventors: Chris Rehse, Emrah Düzel, David Berron, Julian Haupenthal
  • Publication number: 20210062222
    Abstract: Nanostraws and to methods of utilizing them in order to deliver biologically relevant molecules such as DNA, RNA, proteins etc., into non-adherent cells such as immune cells, embryos, plant cells, bacteria, yeast etc. The methods described herein are repeatedly capable of delivering biologically relevant cargo into non-adherent cells, with high cell viability, dosage control, unaffected proliferation or cellular development, and with high efficiency. Among other uses, these new delivery methods will allow to scale pre-clinical cell reprogramming techniques to clinical applications.
    Type: Application
    Filed: October 27, 2020
    Publication date: March 4, 2021
    Inventors: Karl Martin HJORT, Sergio LEAL-ORTIZ, Yuhong CAO, Chris REHSE, Andy Kah Ping TAY, Nicholas A. MELOSH
  • Patent number: 10815499
    Abstract: Nanostraws and to methods of utilizing them in order to deliver biologically relevant molecules such as DNA, RNA, proteins etc., into non-adherent cells such as immune cells, embryos, plant cells, bacteria, yeast etc. The methods described herein are repeatedly capable of delivering biologically relevant cargo into non-adherent cells, with high cell viability, dosage control, unaffected proliferation or cellular development, and with high efficiency. Among other uses, these new delivery methods will allow to scale pre-clinical cell reprogramming techniques to clinical applications.
    Type: Grant
    Filed: July 17, 2018
    Date of Patent: October 27, 2020
    Assignee: The Board of Trustees of the Leland Stanford Junior University
    Inventors: Karl Martin Hjort, Sergio Leal-Ortiz, Yuhong Cao, Chris Rehse, Andy Kah Ping Tay, Nicholas A. Melosh
  • Publication number: 20190365803
    Abstract: Methods and apparatuses for extracting, modifying and returning cells to/from a patient to treat the patient. These apparatuses and methods may use nanostraws to deliver biologically relevant molecules such as DNA, RNA, proteins etc., into the cells rapidly and efficiently. The methods and apparatuses described herein are repeatedly capable of delivering biologically relevant cargo into cells with high cell viability, dosage control, unaffected proliferation or cellular development, and with high efficiency, including in a continuous or semi-continuous manner.
    Type: Application
    Filed: June 4, 2019
    Publication date: December 5, 2019
    Inventors: Nicholas A. MELOSH, Sergio LEAL-ORTIZ, Chris REHSE, Ryan SWOBODA, Craig GARNER
  • Publication number: 20190024122
    Abstract: Nanostraws and to methods of utilizing them in order to deliver biologically relevant molecules such as DNA, RNA, proteins etc., into non-adherent cells such as immune cells, embryos, plant cells, bacteria, yeast etc. The methods described herein are repeatedly capable of delivering biologically relevant cargo into non-adherent cells, with high cell viability, dosage control, unaffected proliferation or cellular development, and with high efficiency. Among other uses, these new delivery methods will allow to scale pre-clinical cell reprogramming techniques to clinical applications.
    Type: Application
    Filed: July 17, 2018
    Publication date: January 24, 2019
    Inventors: Karl Martin HJORT, Sergio LEAL-ORTIZ, Yuhong CAO, Chris REHSE, Andy Kah Ping TAY, Nicholas A. MELOSH
  • Publication number: 20180360340
    Abstract: The invention relates to a device for neurovascular stimulation, at least comprising: at least one brain activity sensor, at least one cardiovascular sensor, at least one computing unit and at least one output unit. The computing unit comprises at least one task algorithm, wherein signals of at least the brain activity sensor and the cardiovascular sensor can be received by the computing unit, and wherein a task, which is in correlation with at least the signals from at least the brain activity sensor and the signals of the cardiovascular sensor, can be determined by means of the task algorithm and can be output by means of the output unit.
    Type: Application
    Filed: December 13, 2016
    Publication date: December 20, 2018
    Inventors: Chris REHSE, Emrah DÜZEL