Abstract: Compositions and methods described in this document make use of macrophage derived engineered vesicles (MEV) having specificity for delivery to a target environment, for use in modifying macrophage phenotype and/or treating a condition. Further disclosed are MEV derived from a specific phenotype encapsulating a therapeutic agent for targeted therapeutic delivery.

Abstract: A canine diaper with re-useable and removable absorption pad may include a resilient body band which may include a resilient fabric material. The body band may have a first side configured for contacting the body of a desired animal, preferably a dog, and a second side which may be positioned opposite from the first side and away from the body of the animal. A liner may be coupled to the first side at a central region on the body band. A pocket panel may be coupled to the liner and/or first side to form a pocket cavity between the liner and pocket panel. An absorption pad may be removably received in the pocket cavity which may be positioned in contact with the urine emitting organ of the animal. A retainer may be removably coupled to the second side via a fastener, and the retainer may be configured to govern access to the pocket cavity.

Abstract: A smart cap for a medication container is disclosed. The smart cap includes a circuit board and a weight sensor electrically coupled to the circuit board and configured to generate electrical input signals representative of the total weight of medication units in the medication container. The smart cap may include a processor for processing the electrical input signals generated by the weight sensor, and a memory for storing medication information associated with medication in the medication container, including the processed electrical input signals generated by the weight sensor. The smart cap may transmit the stored information to a computing device communicatively coupled to the cap.

Abstract: A compostable food packaging container. The container may have from about 84% to about 94% by weight cPLA, from about 5% to about 15% by weight of an oxygen barrier material, and one or more additives. In some embodiments, the container may be a beverage pod. The oxygen barrier material may be polyglutamic acid in some embodiments. In other embodiments, the oxygen barrier material is ethylene vinyl alcohol. The oxygen barrier material may be a food contact grade material. The one or more additives may include an impact modifier and a nucleating agent in some embodiments. Moreover, the one or more additives may include a pigment. The food packaging container may be formed of a sheet material having one or more layers. The sheet material may be extruded, co-extruded or laminated. In some embodiments, the sheet material may be thermoformed or vacuum formed to form the container.

Abstract: A weight sensor assembly including a strain gauge load cell is disclosed. The weight sensor assembly may be used in a smart cap. The weight sensor includes a platform for weighing objects and a load cell. The load cell includes an annular portion, and first and second beams coupled to the platform. Each of the beams includes a first end fixed to the annular portion and a second end that deforms as the platform displaces downward in response to an applied force. One or more strain gauges are mounted on the beams.

Abstract: A smart cap for a medication container is disclosed. The smart cap includes a circuit board and a weight sensor electrically coupled to the circuit board and configured to generate electrical input signals representative of the total weight of medication units in the medication container. The smart cap may include a processor for processing the electrical input signals generated by the weight sensor, and a memory for storing medication information associated with medication in the medication container, including the processed electrical input signals generated by the weight sensor. The smart cap may transmit the stored information to a computing device communicatively coupled to the cap.

Abstract: A product package for retail display includes a first portion connected to a second portion. The first portion is adapted to receive, contain and completely enclosed products, which the second connected portion is adapted to receive, contain and partially enclose a product for display. By partially enclosing the product, the consumer can test the ergonomics of the device (e.g., a game controller) before purchasing the same. The first portion provides a secure section where accessory items related to the partially enclosed product may be safely contained and displayed.