Patents by Inventor Chris Rowe Taitt
Chris Rowe Taitt has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).
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Patent number: 10220364Abstract: Disclosed herein is a method of: treating an organic polymer with an electron beam-generated plasma; exposing the treated polymer to air or an oxygen- and hydrogen-containing gas, generating hydroxyl groups on the surface of the polymer; reacting the surface with an organosilane compound having a chloro, fluoro, or alkoxy group and a functional or reactive group that is less reactive with the surface than the chloro, fluoro, or alkoxy group; and covalently immobilizing a biomolecule to the functional or reactive group or a reaction product thereof.Type: GrantFiled: April 13, 2018Date of Patent: March 5, 2019Assignee: The United States of America, as represented by the Secretary of the NavyInventors: Stella H. North, Evgeniya H. Lock, Scott G. Walton, Chris Rowe Taitt
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Publication number: 20180229205Abstract: Disclosed herein is a method of: treating an organic polymer with an electron beam-generated plasma; exposing the treated polymer to air or an oxygen- and hydrogen-containing gas, generating hydroxyl groups on the surface of the polymer; reacting the surface with an organosilane compound having a chloro, fluoro, or alkoxy group and a functional or reactive group that is less reactive with the surface than the chloro, fluoro, or alkoxy group; and covalently immobilizing a biomolecule to the functional or reactive group or a reaction product thereof.Type: ApplicationFiled: April 13, 2018Publication date: August 16, 2018Applicant: The Government of the United States of America, as represented by the Secretary of the NavyInventors: Stella H. North, Evgeniya H. Lock, Scott G. Walton, Chris Rowe Taitt
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Patent number: 9962676Abstract: Disclosed herein is a method of: treating an organic polymer with an electron beam-generated plasma; exposing the treated polymer to air or an oxygen- and hydrogen-containing gas, generating hydroxyl groups on the surface of the polymer; reacting the surface with an organosilane compound having a chloro, fluoro, or alkoxy group and a functional or reactive group that is less reactive with the surface than the chloro, fluoro, or alkoxy group; and covalently immobilizing a biomolecule to the functional or reactive group or a reaction product thereof.Type: GrantFiled: March 31, 2015Date of Patent: May 8, 2018Assignee: The United States of America, as represented by the Secretary of the NavyInventors: Stella H. North, Evgeniya H. Lock, Scott G. Walton, Chris Rowe Taitt
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Patent number: 9581594Abstract: Porphyrin-modified antimicrobial peptides as described here may be used as indicators of the presence of microbial targets. Their application may be as (for example) (1) fluorescent indicators in a microarray format, (2) fluorescence or absorbance based indicators in traditional solution based applications, or (3) reflectance based indicators for use in reagent-less detection platforms.Type: GrantFiled: March 13, 2014Date of Patent: February 28, 2017Assignee: The United States of America, as represented by the Secretary of the NavyInventors: Chris Rowe Taitt, Brandy J. White
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Publication number: 20160228840Abstract: Disclosed herein is a method of: treating an organic polymer with an electron beam-generated plasma; exposing the treated polymer to air or an oxygen- and hydrogen-containing gas, generating hydroxyl groups on the surface of the polymer; reacting the surface with an organosilane compound having a chloro, fluoro, or alkoxy group and a functional or reactive group that is less reactive with the surface than the chloro, fluoro, or alkoxy group; and covalently immobilizing a biomolecule to the functional or reactive group or a reaction product thereof.Type: ApplicationFiled: March 31, 2015Publication date: August 11, 2016Applicant: The Governmnet of the United States of America, as represented by the Secretary of the NavyInventors: Stella H. North, Evgeniya H. Lock, Scott G. Walton, Chris Rowe Taitt
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Patent number: 9182392Abstract: Disclosed herein is a method of: treating an organic polymer with an electron beam-generated plasma; exposing the treated polymer to air or an oxygen- and hydrogen-containing gas, generating hydroxyl groups on the surface of the polymer; reacting the surface with an organosilane compound having a chloro, fluoro, or alkoxy group and a functional or reactive group that is less reactive with the surface than the chloro, fluoro, or alkoxy group; and covalently immobilizing a biomolecule to the functional or reactive group or a reaction product thereof.Type: GrantFiled: February 7, 2014Date of Patent: November 10, 2015Assignee: The United States of America, as represented by the Secretary of the NavyInventors: Stella H. North, Evgeniya H. Lock, Scott G. Walton, Chris Rowe Taitt
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Patent number: 8945856Abstract: A method of biochemical identification by: providing a plurality of capture species bound to one or more substrates and suspected of having one or more biological targets affinity bound to at least one capture species; detecting which capture species contain bound biological targets to generate a binding pattern; and identifying the biological target based on the binding pattern. The capture species are independently selected from the group consisting of antimicrobial peptides, cytotoxic peptides, antibiotics, and combinations thereof. A device having the capture species bound to the substrates. At least two of the capture species are capable of multi-specific binding to one or more biological targets and may have overlapping but not identical affinity properties.Type: GrantFiled: February 25, 2014Date of Patent: February 3, 2015Assignee: The United States of America, as represented by the Secretary of the NavyInventors: Nadezhda V. Kulagina, Chris Rowe Taitt, George P. Anderson, Frances S. Ligler
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Publication number: 20140274776Abstract: Porphyrin-modified antimicrobial peptides as described here may be used as indicators of the presence of microbial targets. Their application may be as (for example) (1) fluorescent indicators in a microarray format, (2) fluorescence or absorbance based indicators in traditional solution based applications, or (3) reflectance based indicators for use in reagent-less detection platforms.Type: ApplicationFiled: March 13, 2014Publication date: September 18, 2014Applicant: The Government of the United States of America, as represented by the Secretary of the NavyInventors: Chris Rowe Taitt, Brandy J. White
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Publication number: 20140187446Abstract: A method of biochemical identification by: providing a plurality of capture species bound to one or more substrates and suspected of having one or more biological targets affinity bound to at least one capture species; detecting which capture species contain bound biological targets to generate a binding pattern; and identifying the biological target based on the binding pattern. The capture species are independently selected from the group consisting of antimicrobial peptides, cytotoxic peptides, antibiotics, and combinations thereof. A device having the capture species bound to the substrates. At least two of the capture species are capable of multi-specific binding to one or more biological targets and may have overlapping but not identical affinity properties.Type: ApplicationFiled: February 25, 2014Publication date: July 3, 2014Applicant: The Government of the United States of America, as represented by the Secretary of the NavyInventors: Nadezhda V. Kulagina, Chris Rowe Taitt, George P. Anderson, Frances S. Ligler
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Publication number: 20140154791Abstract: Disclosed herein is a method of: treating an organic polymer with an electron beam-generated plasma; exposing the treated polymer to air or an oxygen- and hydrogen-containing gas, generating hydroxyl groups on the surface of the polymer; reacting the surface with an organosilane compound having a chloro, fluoro, or alkoxy group and a functional or reactive group that is less reactive with the surface than the chloro, fluoro, or alkoxy group; and covalently immobilizing a biomolecule to the functional or reactive group or a reaction product thereof.Type: ApplicationFiled: February 7, 2014Publication date: June 5, 2014Applicant: The Government of the United States of America, as represented by the Secretary of the NavyInventors: Stella H. North, Evgeniya H. Lock, Scott G. Walton, Chris Rowe Taitt
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Patent number: 8658372Abstract: A method of biochemical identification by: providing a plurality of capture species bound to one or more substrates and suspected of having one or more biological targets affinity bound to at least one capture species; detecting which capture species contain bound biological targets to generate a binding pattern; and identifying the biological target based on the binding pattern. The capture species are independently selected from the group consisting of antimicrobial peptides, cytotoxic peptides, antibiotics, and combinations thereof. A device having the capture species bound to the substrates. At least two of the capture species are capable of multi-specific binding to one or more biological targets and may have overlapping but not identical affinity properties.Type: GrantFiled: February 6, 2006Date of Patent: February 25, 2014Assignee: The United States of America, as represented by the Secretary of the NavyInventors: Nadezhda V Kulagina, Chris Rowe Taitt, George P Anderson, Frances S Ligler
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Patent number: 8651158Abstract: Disclosed herein is a method of: treating an organic polymer with an electron beam-generated plasma; exposing the treated polymer to air or an oxygen- and hydrogen-containing gas, generating hydroxyl groups on the surface of the polymer; reacting the surface with an organosilane compound having a chloro, fluoro, or alkoxy group and a functional or reactive group that is less reactive with the surface than the chloro, fluoro, or alkoxy group; and covalently immobilizing a biomolecule to the functional or reactive group or a reaction product thereof.Type: GrantFiled: November 17, 2010Date of Patent: February 18, 2014Assignee: The United States of America, as represented by the Secretary of the NavyInventors: Stella H. North, Evgeniya H. Lock, Scott G. Walton, Chris Rowe Taitt
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Publication number: 20110116992Abstract: Disclosed herein is a method of: treating an organic polymer with an electron beam-generated plasma; exposing the treated polymer to air or an oxygen- and hydrogen-containing gas, generating hydroxyl groups on the surface of the polymer; reacting the surface with an organosilane compound having a chloro, fluoro, or alkoxy group and a functional or reactive group that is less reactive with the surface than the chloro, fluoro, or alkoxy group; and covalently immobilizing a biomolecule to the functional or reactive group or a reaction product thereof.Type: ApplicationFiled: November 17, 2010Publication date: May 19, 2011Applicant: The Government of the United States of America, as represented by the Secretary of the NavyInventors: Stella H. North, Evgeniya H. Lock, Scott G. Walton, Chris Rowe Taitt