Patents by Inventor Chris Tselepis

Chris Tselepis has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Patent number: 10138261
    Abstract: A ferrocenyl compound having the general formula (I): (I) Het is a substituted or unsubstituted heterocyclic moiety. L1, L2 and L3 are each a linker independently selected from alkylene, alkyleneoxy, alkyleneoxyalkylene, alkylenecarbonyl, alkyleneoxycarbonyl, alkyleneamido, alkyleneoxyamido, alkenylene, alkenyleneoxy, alkenylenecarbonyl, alkenyleneamido, alkynylene, alkynyleneoxy, alkynylenecarbonyl and alkynyleneamido, all of which may be straight chain or branched, substituted or unsubstituted. R1 and R2 are each independently selected from H, substituted or unsubstituted alkyl carbonyl, substituted or unsubstituted aryl carbonyl, substituted or unsubstituted phosphate, substituted or unsubstituted phosphonate and substituted or unsubstituted phosphoramidate. M and n are each 0 or 1 and m+n?0.1.
    Type: Grant
    Filed: December 19, 2014
    Date of Patent: November 27, 2018
    Assignee: THE UNIVERSITY OF BIRMINGHAM EDGBASTON
    Inventors: Chris Tselepis, James Tucker, Huy Van Nguyen, Nikolas John Hodges, Youcef Mehellou
  • Publication number: 20160318964
    Abstract: A ferrocenyl compound having the general formula (I): (I) Het is a substituted or unsubstituted heterocyclic moiety. L1, L2 and L3 are each a linker independently selected from alkylene, alkyleneoxy, alkyleneoxyalkylene, alkylenecarbonyl, alkyleneoxycarbonyl, alkyleneamido, alkyleneoxyamido, alkenylene, alkenyleneoxy, alkenylenecarbonyl, alkenyleneamido, alkynylene, alkynyleneoxy, alkynylenecarbonyl and alkynyleneamido, all of which may be straight chain or branched, substituted or unsubstituted. R1 and R2 are each independently selected from H, substituted or unsubstituted alkyl carbonyl, substituted or unsubstituted aryl carbonyl, substituted or unsubstituted phosphate, substituted or unsubstituted phosphonate and substituted or unsubstituted phosphoramidate. M and n are each 0 or 1 and m+n?0.
    Type: Application
    Filed: December 19, 2014
    Publication date: November 3, 2016
    Inventors: Chris Tselepis, James Tucker, Huy Van Nguyen, Nikolas John Hodges, Youcef Mehellou
  • Publication number: 20160296629
    Abstract: A complex comprising a non-absorbable portion attached to an iron chelator moiety, a composition comprising the complex and the use of the complex in the treatment of colorectal cancer. In one embodiment the non-absorbable portion is a polymer such as a polysaccharide, including chitosan, chitin, cellulose or pectin. In one embodiment the iron chelator moiety comprises at least one functional group selected from catechol, hydroxamate or carboxylate, or any combination thereof.
    Type: Application
    Filed: November 28, 2014
    Publication date: October 13, 2016
    Applicant: THE UNIVERSITY OF BIRMINGHAM
    Inventors: Chris Tselepis, John S. Fossey, Rama Byravan
  • Patent number: 9421220
    Abstract: Biologically acceptable composition for the prophylaxis and/or treatment of colorectal cancer. The composition contains an iron chelator, and the composition is adapted for the selective targeting of the iron chelator to the colon. The iron chelator is non-digestible, non-absorbable and non-fermentable in the gastrointestinal tract.
    Type: Grant
    Filed: October 26, 2010
    Date of Patent: August 23, 2016
    Assignee: THE UNIVERSITY OF BIRMINGHAM EDGBASTON
    Inventors: Chris Tselepis, Tariq Iqbal, Owen James Sansom
  • Publication number: 20120276163
    Abstract: The present invention relates to a biologically acceptable composition for the prophylaxis and/or treatment of colorectal cancer comprising an iron chelator, wherein the composition is adapted for the selective targeting of the iron chelator to the colon.
    Type: Application
    Filed: October 26, 2010
    Publication date: November 1, 2012
    Inventors: Chris Tselepis, Tariq Iqbal, Owen James Sansom