Abstract: Cartridge for the detection of the presence, absence and/or amount of a target nucleotide sequence in a sample. The cartridge includes one or more nucleic acid sequences, wherein the cartridge has a generic part and one or more separate application-specific parts, which are connectable to the generic part.

Abstract: Cartridge and method for the detection of the presence, absence and/or amount of a target nucleotide sequence in a sample comprising one or more nucleic acid sequences. The cartridge comprises a one or more nucleic acid sequences, and the cartridge includes a generic part and one or more separate application-specific parts, which are connectable to the generic part.

Abstract: The present invention relates to a cartridge for the detection of the presence, absence and/or amount of a target nucleotide sequence in a sample comprising one or more nucleic acid sequences. The cartridge comprises a first component and a second component being connectable to each other, the first component comprising at least a first fluid opening and a first sealing surface and the second component comprising at least a second fluid opening and a second sealing surface. Upon connection of the first and second component the first and second fluid opening are placeable in fluid communication and the first and second sealing surfaces are placeable against each other to seal the fluid communication between the first and second fluid opening. The invention is characterized in that the cartridge comprises biasing means for biasing the second sealing surface in the direction of the first sealing surface.

Abstract: A micro fluidic device includes a valve/pump-unit with reduced dead volume having a substrate. The lower surface of the substrate includes two micro channels spaced apart by a valve area of the substrate that separates the two micro channels. A flexible membrane is arranged on the lower surface of the substrate facing an actuating element located in a through going cut-out of a cover element. Movement of the actuating element towards and away from the valve area of the substrate causes a pump and/or valve action of the flexible membrane area, respectively, to cause or stop a directed fluid flow between the two micro channels through a channel formed between the valve area of the substrate and the flexible membrane.

Abstract: The invention provides a device for mixing a liquid medium, an apparatus for mixing a liquid medium, a system comprising a device and an apparatus and a method for mixing a liquid medium. The device comprises a flexible membrane (12) and a structural part (16), which device further comprises an actuation part (14) located on a first side of the membrane, which device further comprises a mixing chamber (20) located on a second side of the membrane, wherein at least a partial inclination of the membrane results from an inclination of the actuation part relative to the structural part.

Abstract: The invention provides an apparatus for moving magnetic particles in a liquid medium, a system comprising an apparatus, a method for moving magnetic particles and a method for moving and for fixing the magnetic particles. The apparatus comprises a first magnetic means generating a first magnetic field, the apparatus further comprising a second magnetic means generating a second magnetic field, the first magnetic field having a first main axis, the second magnetic field having a second main axis, wherein the first and second main axes are inclined relative to each other by an acute angle of inclination.

Abstract: The present invention relates to a cartridge for the detection of the presence, absence and/or amount of a target nucleotide sequence in a sample comprising one or more nucleic acid sequences. The cartridge comprises a first component and a second component being connectable to each other, the first component comprising at least a first fluid opening and a first sealing surface and the second component comprising at least a second fluid opening and a second sealing surface. Upon connection of the first and second component the first and second fluid opening are placeable in fluid communication and the first and second sealing surfaces are placeable against each other to seal the fluid communication between the first and second fluid opening. The invention is characterized in that the cartridge comprises biasing means for biasing the second sealing surface in the direction of the first sealing surface.

Abstract: The present invention is directed to a micro fluidic device (1) comprising at least one valve/pump-unit (2) with reduced dead volume, wherein the micro fluid device comprises: —a substrate (3), wherein on the lower surface of said substrate (3) at least two micro channels (4) are arranged to direct a fluid sample (5) flow on the substrate (3), whereby said two micro channels (4) are not end-to-end connected and spaced apart by a valve area (6) of said substrate (3); —at least one flexible membrane (7), wherein the flexible membrane (7) is arranged on the lower surface of said substrate (3); —an actuating element (8) with an upper surface (9) adjacent arranged to the flexible membrane (7); —at least one cover element (10) arranged on the lower surface of the flexible membrane (7), wherein the cover element (10) comprises at least one through going cut-out (11) for receiving an actuating element (8), so that movement of said actuating element (8) causes a pump and/or valve action of the adjacent arranged flexib

Abstract: Disclosed is a cartridge for the detection of the presence, absence and/or amount of a target nucleotide sequence in a sample comprising one or more nucleic acid sequences. The cartridge comprises a generic part and one or more separate application-specific parts, which are connectable to the generic part. Also disclosed is a system for the detection of the presence, absence and/or amount of a target nucleotide sequence in a sample comprising one or more nucleic acid sequences. This system comprising a reusable apparatus, wherein said apparatus is configured to receive a cartridge and to control a process for the detection of the presence, absence and/or amount of a target nucleotide sequence in the sample, being present in said cartridge.

Abstract: The invention provides a device for mixing a liquid medium, an apparatus for mixing a liquid medium, a system comprising a device and an apparatus and a method for mixing a liquid medium. The device comprises a flexible membrane (12) and a structural part (16), which device further comprises an actuation part (14) located on a first side of the membrane, which device further comprises a mixing chamber (20) located on a second side of the membrane, wherein at least a partial inclination of the membrane results from an inclination of the actuation part relative to the structural part.

Abstract: The invention provides a system, a processing apparatus, a sample unit, a reagent unit and a method for processing a biological sample in the inside of the sample unit. The system comprises at least a processing apparatus and a sample unit, the sample unit comprises a plurality of microfluidic elements, the processing apparatus comprises actuation means capable of actuating at the microfluidic elements such that a quick, cheap and accurate analysis of the biological sample is possible.