Abstract: The hemitartrate salt of a compound represented by the following structural formula: (Formula I Hemitartrate), which may be used in pharmaceutical applications, are disclosed. Particular single crystalline forms of the Formula (I) Hemitartrate are characterized by a variety of properties and physical measurements. As well, methods of producing crystalline Formula (I) Hemitartrate, and using it to inhibit glucosylceramide synthase or lowering glycosphingolipid concentrations in subjects to treat a number of diseases, are also discussed. Pharmaceutical compositions are also described.

Abstract: The hemitartrate salt of a compound represented by the following structural formula: (Formula I Hemitartrate), which may be used in pharmaceutical applications, are disclosed. Particular single crystalline forms of the Formula (I) Hemitartrate are characterized by a variety of properties and physical measurements. As well, methods of producing crystalline Formula (I) Hemitartrate, and using it to inhibit glucosylceramide synthase or lowering glycosphingolipid concentrations in subjects to treat a number of diseases, are also discussed. Pharmaceutical compositions are also described.

Abstract: Techniques are disclosed for calibration systems and methods for analyte detectors. In one example, a system may include a calibration device configured to operate with an analyte detector. The calibration device may include a chamber configured to receive a sample and pass at least a portion of the sample including analytes to the analyte detector for examination. The calibration device may further include a reservoir including a calibrant and configured to be selectively positioned in the chamber as the sample to provide the portion of the sample including the analytes to calibrate the analyte detector. Additional systems and related methods are provided.

Abstract: A visualization combination engine may be used to combine a first data visualization based on a first data set with a second data visualization based on a second data set. The combination process may be initiated by, for example, clicking and dragging the first data visualization onto the second data visualization. The visualization combination engine may create the combined data visualization without requiring the user to manually combine the first and second data sets. The combination may be carried out by identifying a key that is common between the two data sets and combining the first and second data sets into a combined data set based on the key, and then creating the combined data visualization based on the combined data set. One or more cues may be used during the process to provide helpful information and/or allow user selection of the properties of the combined data visualization.

Abstract: A user interface is provided for allowing a user to interact with a graphical display. Quantitative data is initially displayed in a graphical format representing absolute values. A comparative graph is also made available, either automatically or in response to user input; the comparative graph presents each data entry according to its relative value as compared with one specific baseline entry.

Abstract: Various techniques are provided to implement, operate, and manufacture a chemical detection device. In one embodiment, a device includes a flow path comprising an analyte reporter configured to receive samples passed by the flow path. The device also includes an excitation source configured generate a response from the analyte reporter. The device also includes a detector configured to receive the response from the analyte reporter to determine whether the samples comprise a material of interest. The device also includes a support structure configured to position the flow path relative to the excitation source and the detector, wherein the support structure comprises a carbon filled polymer material. Additional devices, systems, and methods are also provided.

Abstract: The hemitartrate salt of a compound represented by the following structural formula: (Formula 1 Hemitartrate), which may be used in pharmaceutical applications, are disclosed. Particular single crystalline forms of the Formula (I) Hemitartrate are characterized by a variety of properties and physical measurements. As well, methods of producing crystalline Formula (I) Hemitartrate, and using it to inhibit glucosylceramide synthase or lowering glycosphingolipid concentrations in subjects to treat a number of diseases, are also discussed. Pharmaceutical compositions are also described.

Abstract: The hemitartrate salt of a compound represented by the following structural formula: (Formula I Hemitartrate), which may be used in pharmaceutical applications, are disclosed. Particular single crystalline forms of the Formula (I) Hemitartrate are characterized by a variety of properties and physical measurements. As well, methods of producing crystalline Formula (I) Hemitartrate, and using it to inhibit glucosylceramide synthase or lowering glycosphingolipid concentrations in subjects to treat a number of diseases, are also discussed. Pharmaceutical compositions are also described.

Abstract: Various techniques are provided to implement, operate, and manufacture a chemical detection device. In one embodiment, a device includes a flow path comprising an analyte reporter configured to receive samples passed by the flow path. The device also includes an excitation source configured generate a response from the analyte reporter. The device also includes a detector configured to receive the response from the analyte reporter to determine whether the samples comprise a material of interest. The device also includes a support structure configured to position the flow path relative to the excitation source and the detector, wherein the support structure comprises a carbon filled polymer material. Additional devices, systems, and methods are also provided.

Abstract: An alert may provide a user with notification when a trigger condition regarding the operation of an enterprise is satisfied. Prior to setting the alert, a proposed alert with the trigger condition may be received. The trigger condition may be compared with a database of operational data related to operation of the enterprise over a period of time to obtain historical trigger data. The historical trigger data may indicate how the proposed alert would have functioned if applied to the operational data for the period of time, for example, by indicating how many times the alert would have been triggered during the period of time. The historical trigger data may be provided to a user, and may facilitate user determination of whether the proposed alert will perform as desired. Once the desired proposed alert has been entered, the user may set the proposed alert as an actual alert.

Abstract: A user interface is provided for allowing a user to interact with a graphical display. Quantitative data is initially displayed in a graphical format representing absolute values. A comparative graph is also made available, either automatically or in response to user input; the comparative graph presents each data entry according to its relative value as compared with one specific baseline entry.

Abstract: A visualization combination engine may be used to combine a first data visualization based on a first data set with a second data visualization based on a second data set. The combination process may be initiated by, for example, clicking and dragging the first data visualization onto the second data visualization. The visualization combination engine may create the combined data visualization without requiring the user to manually combine the first and second data sets. The combination may be carried out by identifying a key that is common between the two data sets and combining the first and second data sets into a combined data set based on the key, and then creating the combined data visualization based on the combined data set. One or more cues may be used during the process to provide helpful information and/or allow user selection of the properties of the combined data visualization.

Abstract: A visualization combination engine may be used to combine a first data visualization based on a first data set with a second data visualization based on a second data set. The combination process may be initiated by, for example, clicking and dragging the first data visualization onto the second data visualization. The visualization combination engine may create the combined data visualization without requiring the user to manually combine the first and second data sets. The combination may be carried out by identifying a key that is common between the two data sets and combining the first and second data sets into a combined data set based on the key, and then creating the combined data visualization based on the combined data set. One or more cues may be used during the process to provide helpful information and/or allow user selection of the properties of the combined data visualization.

Abstract: An alert may provide a user with notification when a trigger condition regarding the operation of an enterprise is satisfied. Prior to setting the alert, a proposed alert with the trigger condition may be received. The trigger condition may be compared with a database of operational data related to operation of the enterprise over a period of time to obtain historical trigger data. The historical trigger data may indicate how the proposed alert would have functioned if applied to the operational data for the period of time, for example, by indicating how many times the alert would have been triggered during the period of time. The historical trigger data may be provided to a user, and may facilitate user determination of whether the proposed alert will perform as desired. Once the desired proposed alert has been entered, the user may set the proposed alert as an actual alert.

Abstract: Techniques are disclosed for calibration systems and methods for analyte detectors. In one example, a system may include a calibration device configured to operate with an analyte detector. The calibration device may include a chamber configured to receive a sample and pass at least a portion of the sample including analytes to the analyte detector for examination. The calibration device may further include a reservoir including a calibrant and configured to be selectively positioned in the chamber as the sample to provide the portion of the sample including the analytes to calibrate the analyte detector. Additional systems and related methods are provided.

Abstract: Various techniques are provided to implement a desorber of a sensor detector device that permits manual operation and is completely detachable from a main body of the sensor detector device. In one example, a device includes a desorber. The desorber includes an inlet comprising a fluid path configured to receive samples vaporized from sample media. The desorber also includes a cap configured to slide toward the inlet in response to a manual actuation of the cap performed by a user to transition the desorber from an open position to a closed position. The desorber further includes a heater configured to slide with the cap toward the inlet in response to the user actuation and vaporize the samples while the desorber is in the closed position.

Abstract: An alert may provide a user with notification when a trigger condition regarding the operation of an enterprise is satisfied. Prior to setting the alert, a proposed alert with the trigger condition may be received. The trigger condition may be compared with a database of operational data related to operation of the enterprise over a period of time to obtain historical trigger data. The historical trigger data may indicate how the proposed alert would have functioned if applied to the operational data for the period of time, for example, by indicating how many times the alert would have been triggered during the period of time. The historical trigger data may be provided to a user, and may facilitate user determination of whether the proposed alert will perform as desired. Once the desired proposed alert has been entered, the user may set the proposed alert as an actual alert.

Abstract: An alert may provide a user with notification when a trigger condition regarding the operation of an enterprise is satisfied. Prior to setting the alert, a proposed alert with the trigger condition may be received. The trigger condition may be compared with a database of operational data related to operation of the enterprise over a period of time to obtain historical trigger data. The historical trigger data may indicate how the proposed alert would have functioned if applied to the operational data for the period of time, for example, by indicating how many times the alert would have been triggered during the period of time. The historical trigger data may be provided to a user, and may facilitate user determination of whether the proposed alert will perform as desired. Once the desired proposed alert has been entered, the user may set the proposed alert as an actual alert.