Abstract: The present disclosure is directed to a portable system and method for modulating targeted neural and non-neural tissue of a nervous system to block nerve conduction for the treatment of pain. A high-efficiency portable electrical stimulation system is provided that allows a user to carry the system and move around freely while continuously receiving therapy. The electronic control system is configured to deliver high-frequency electrical stimulation at a therapeutic level, for an intended duration (e.g., up to 24 hours or more) at a manageable and/or comfortable weight for a person, to the target nerve.

Abstract: The present disclosure is directed to a portable system and method for modulating targeted neural and non-neural tissue of a nervous system to block nerve conduction for the treatment of pain. A high-efficiency portable electrical stimulation system is provided that allows a user to carry the system and move around freely while continuously receiving therapy. The electronic control system is configured to deliver high-frequency electrical stimulation at a therapeutic level, for an intended duration (e.g., up to 24 hours or more) at a manageable and/or comfortable weight for a person, to the target nerve.

Abstract: An ultrasonic Doppler flow (i.e. blood) imaging and/or measuring system capable of adaptively suppressing stationary or slowly-moving non-flow (i.e. blood) signals having variable spectra from the recovered ultrasonic echoes. In accordance with the invention, the tissue signals are suppressed using a tissue rejection filter arrangement having an attenuation characteristic which is controlled based upon measured estimates of at least one spectral characteristic of the tissue signals to be removed, thereby maximizing the rejection of tissue movement signals and minimizing undesired attenuation of the blood flow signals. In accordance with an embodiment of the invention, data representative of the tissue signal movement, e.g., the spectral estimates of the tissue signals, are spatially averaged before being used to control the tissue rejection filter arrangement.