Patents by Inventor Christa Schleper

Christa Schleper has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Archaeon expression system
    Patent number: 8679829
    Abstract: The present invention relates to a sulfolobus expression vector comprising: (a) sulfolobus origin of replication; (b) the genes encoding the structural proteins and the site-specific integrase of SSV1, SSV2 or pSSVx, operatively linked to expression control sequences and a packaging signal; (c) one or more selectable marker gene(s), operatively linked to sulfolobus expression control sequences; and (d) a sulfolobus promoter followed 3? by a restriction enzyme recognition site or a multiple cloning site for insertion of a gene of interest and optionally a 3? regulatory element. Moreover, the present invention relates to a shuttle vector comprising the sequences of the expression vector of the invention and additional sequences for propagation and selection in E. coli, wherein the additional sequences comprise (a) an E. coli on of replication; and (b) a marker for selection in E. coli.
    Type: Grant
    Filed: June 2, 2004
    Date of Patent: March 25, 2014
    Assignee: B.R.A.I.N. Biotechnology Research and Information Network AG
    Inventors: Christa Schleper, Melanie Jonuscheit, Jürgen Eck, Frank Niehaus, Sonja-Verena Albers, Sabrina Froels
  • Isolation and cloning of DNA from uncultivated organisms
    Patent number: 7749366
    Abstract: The present invention relates to a device for the isolation and/or purification of nucleic acid molecules suitable to bind and/or inactivate inhibitors of the activity of reagents or enzymes used for DNA manipulation and to separate a plurality of nucleic acid molecules with respect to their size. Moreover, the invention relates to a method for the isolation of a nucleic acid molecule comprising applying a sample to the device of the invention wherein said nucleic acid molecule preferably represents a fraction of the metagenome of a given habitat. Furthermore, the invention relates to a method for the generation of at least one gene library comprising nucleic acid molecules isolated by the method of the invention and to a nucleic acid molecule isolated by the method of the invention.
    Type: Grant
    Filed: August 20, 2003
    Date of Patent: July 6, 2010
    Assignee: B.R.A.I.N. Biotechnology Research and Information Network AG
    Inventors: Achim Quaiser, Torsten Ochsenreiter, Alexander H. Treusch, Arnulf Kletzin, Christa Schleper, Patrick Lorenz, Jürgen Eck
  • Archaeon expression system
    Publication number: 20070134201
    Abstract: The present invention relates to a sulfolobus expression vector comprising: (a) sulfolobus origin of replication; (b) the genes encoding the structural proteins and the site-specific integrase of SSV1, SSV2 or pSSVx, operatively linked to expression control sequences and a packaging signal; (c) one or more selectable marker gene(s), operatively linked to sulfolobus expression control sequences; and (d) a sulfolobus promoter followed 3? by a restriction enzyme recognition site or a multiple cloning site for insertion of a gene of interest and optionally a 3? regulatory element. Moreover, the present invention relates to a shuttle vector comprising the sequences of the expression vector of the invention and additional sequences for propagation and selection in E. coli, wherein the additional sequences comprise (a) an E. coli on of replication; and (b) a marker for selection in E. coli.
    Type: Application
    Filed: June 2, 2004
    Publication date: June 14, 2007
    Applicant: B.R.A.I.N. Biotechnology Research and Information Network AG
    Inventor: Christa Schleper
  • Isolation and cloning of dna from uncultivated organisms
    Publication number: 20060240423
    Abstract: The present invention relates to a device for the isolation and/or purification of nucleic acid molecules suitable to bind and/or inactivate inhibitors of the activity of reagents or enzymes used for DNA manipulation and to separate a plurality of nucleic acid molecules with respect to their size. Moreover, the invention relates to a method for the isolation of a nucleic acid molecule comprising applying a sample to the device of the invention wherein said nucleic acid molecule preferably represents a fraction of the metagenome of a given habitat. Furthermore, the invention relates to a method for the generation of at least one gene library comprising nucleic acid molecules isolated by the method of the invention and to a nucleic acid molecule isolated by the method of the invention.
    Type: Application
    Filed: August 20, 2003
    Publication date: October 26, 2006
    Applicant: B.R.A.I.N. Biotechnology Research And Information Networg AG
    Inventors: Achim Quaiser, Torsten Ochsenreiter, Alexander Treusch, Arnulf Kletzin, Christa Schleper, Patrick Lorenz, Jurgen Eck
  • Nucleic acids and proteins from Cenarchaeum symbiosum
    Patent number: 6632937
    Abstract: The present application relates to nucleic acids and polypeptides from Cenarchaeum symbiosum. Methods of making the polypeptides and antibodies against the polypeptides are also described.
    Type: Grant
    Filed: September 29, 1999
    Date of Patent: October 14, 2003
    Assignee: Diversa Corporation
    Inventors: Ronald V. Swanson, Robert A. Feldman, Christa Schleper
  • Nucleic acids and proteins from cenarchaeum symbiosum
    Publication number: 20030175708
    Abstract: The present application relates to nucleic acids and polypeptides from Cenarchaeum symbiosum. Methods of making the polypeptides and antibodies against the polypeptides are also described.
    Type: Application
    Filed: December 21, 2001
    Publication date: September 18, 2003
    Applicant: Diversa Corporation
    Inventors: Ronald V. Swanson, Robert A. Feldman, Christa Schleper, Edward F. DeLong, Christina M. Preston
  • Nucleic acids and proteins from cenarchaeum symbiosum
    Publication number: 20020198365
    Abstract: The present application relates to nucleic acids and polypeptides from Cenarchaeum symbiosum. Methods of making the polypeptides and antibodies against the polypeptides are also described.
    Type: Application
    Filed: December 21, 2001
    Publication date: December 26, 2002
    Applicant: Diversa Corporation
    Inventors: Ronald V. Swanson, Robert A. Feldman, Christa Schleper, Edward F. DeLong, Christina M. Preston
  • Nucleic acids and proteins from cenarchaeum symbiosum
    Publication number: 20020160476
    Abstract: The present application relates to nucleic acids and polypeptides from Cenarchaeum symbiosum. Methods of making the polypeptides and antibodies against the polypeptides are also described.
    Type: Application
    Filed: December 21, 2001
    Publication date: October 31, 2002
    Applicant: Diversa Corporation
    Inventors: Ronald V. Swanson, Robert A. Feldman, Christa Schleper, Edward F. DeLong, Christina M. Preston