Patents by Inventor Christi L. Clogston

Christi L. Clogston has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Crystalline antibody formulations
    Patent number: 11773184
    Abstract: Described herein are anti-PCSK9 antibody crystals, methods of making such antibody crystals and formulations comprising the antibody crystals.
    Type: Grant
    Filed: February 24, 2020
    Date of Patent: October 3, 2023
    Inventors: Twinkle R. Christian, Christi L. Clogston, Timothy David Osslund
  • Reduced viscosity protein pharmaceutical formulations
    Patent number: 11459401
    Abstract: Described herein are therapeutic protein formulations comprising N-methyl pyrrolidone (NMP), methods related to reducing viscosity of pharmaceutical formulations and methods related to stabilizing pharmaceutical formulations using NMP.
    Type: Grant
    Filed: October 6, 2017
    Date of Patent: October 4, 2022
    Assignee: Amgen Inc.
    Inventors: Alona Teran, Qahera Munaim, Nazer Khalaf, Rahul Rajan Kaushik, Christi L. Clogston, Twinkle R. Christian, William J. Callahan
  • METHODS OF TREATING OR PREVENTING CHOLESTEROL RELATED DISORDERS
    Publication number: 20210047434
    Abstract: The present invention relates to methods of treating or preventing cholesterol related disorders, such as hypercholesterolemia, hyperlipidemia or dyslipidemia, using antibodies against proprotein convertase subtilisin/kexin type 9 (PCSK9). Formulations and methods of producing said formulations are also described.
    Type: Application
    Filed: September 3, 2020
    Publication date: February 18, 2021
    Inventors: Joyce Chi Yee Chan, John P. Gibbs, Clapton S. Dias, Scott Wasserman, Robert Andrew Donald Scott, Christi L. Clogston, Timothy David Osslund, Evan A. Stein
  • CRYSTALLINE ANTIBODY FORMULATIONS
    Publication number: 20200299410
    Abstract: Described herein are anti-PCSK9 antibody crystals, methods of making such antibody crystals and formulations comprising the antibody crystals.
    Type: Application
    Filed: February 24, 2020
    Publication date: September 24, 2020
    Applicant: AMGEN INC.
    Inventors: Twinkle R. CHRISTIAN, Christi L. CLOGSTON, Timothy David OSSLUND
  • Crystalline antibody formulations
    Patent number: 10611850
    Abstract: Described herein are anti-PCSK9 antibody crystals, methods of making such antibody crystals and formulations comprising the antibody crystals.
    Type: Grant
    Filed: July 13, 2015
    Date of Patent: April 7, 2020
    Assignee: Amgen Inc.
    Inventors: Twinkle R. Christian, Christi L. Clogston, Timothy David Osslund
  • REDUCED VISCOSITY PROTEIN PHARMACEUTICAL FORMULATIONS
    Publication number: 20200024363
    Abstract: Described herein are therapeutic protein formulations comprising N-methyl pyrrolidone (NMP), methods related to reducing viscosity of pharmaceutical formulations and methods related to stabilizing pharmaceutical formulations using NMP.
    Type: Application
    Filed: October 6, 2017
    Publication date: January 23, 2020
    Inventors: Alona Teran, Qahera Muniam, Nazer Khalaf, Rahul Rajan Kaushik, Christi L. Clogston, Twinkle R. Christian, William J. Callahan
  • CRYSTALLINE ANTIBODY FORMULATIONS
    Publication number: 20170198058
    Abstract: Described herein are anti-PCSK9 antibody crystals, methods of making such antibody crystals and formulations comprising the antibody crystals.
    Type: Application
    Filed: July 13, 2015
    Publication date: July 13, 2017
    Inventors: Twinkle R. CHRISTIAN, Christi L. CLOGSTON, Timothy David OSSLUND
  • Sclerostin antibody crystals and formulations thereof
    Patent number: 9617333
    Abstract: Described herein are anti-sclerostin antibody crystals, methods of making such antibody crystals and formulations comprising the antibody crystals.
    Type: Grant
    Filed: August 21, 2015
    Date of Patent: April 11, 2017
    Assignee: AMGEN INC.
    Inventors: Christi L. Clogston, Twinkle R. Christian, Timothy D. Osslund, Elisabeth Freeman
  • SCLEROSTIN ANTIBODY CRYSTALS AND FORMULATIONS THEREOF
    Publication number: 20160083460
    Abstract: Described herein are anti-sclerostin antibody crystals, methods of making such antibody crystals and formulations comprising the antibody crystals.
    Type: Application
    Filed: August 21, 2015
    Publication date: March 24, 2016
    Inventors: Christi L. Clogston, Twinkle R. Christian, Timothy D. Osslund, Elisabeth Freeman
  • Sclerostin antibody crystals and formulations thereof
    Patent number: 9145457
    Abstract: Described herein are anti-sclerostin antibody crystals, methods of making such antibody crystals and formulations comprising the antibody crystals.
    Type: Grant
    Filed: March 23, 2012
    Date of Patent: September 29, 2015
    Assignee: AMGEN INC.
    Inventors: Christi L. Clogston, Twinkle R. Christian, Timothy David Osslund, Elisabeth Freeman
  • Crystalline polypeptides
    Patent number: 9012605
    Abstract: Crystalline formulations of therapeutic peptides, along with methods for making and using the same, are provided.
    Type: Grant
    Filed: January 22, 2007
    Date of Patent: April 21, 2015
    Assignee: Amgen Inc.
    Inventor: Christi L. Clogston
  • SCLEROSTIN ANTIBODY CRYSTALS AND FORMULATIONS THEREOF
    Publication number: 20140105909
    Abstract: Described herein are anti-sclerostin antibody crystals, methods of making such antibody crystals and formulations comprising the antibody crystals.
    Type: Application
    Filed: March 23, 2012
    Publication date: April 17, 2014
    Applicant: AMGEN INC.
    Inventors: Christi L. Clogston, Twinkle L. Christian, Timothy D. Osslund, Elisabeth Freeman
  • METHODS OF TREATING OR PREVENTING CHOLESTEROL RELATED DISORDERS
    Publication number: 20130064825
    Abstract: The present invention relates to methods of treating or preventing cholesterol related disorders, such as hypercholesterolemia, hyperlipidemia or dyslipidemia, using antibodies against proprotein convertase subtilisin/kexin type 9 (PCSK9). Formulations and methods of producing said formulations are also described.
    Type: Application
    Filed: May 10, 2012
    Publication date: March 14, 2013
    Applicant: Amgen Inc.
    Inventors: Joyce Chi Yee Chan, John P. Gibbs, Clapton S. Dias, Scott Wasserman, Robert Andrew Donald Scott, Christi L. Clogston, Timothy David Osslund
  • Crystalline Polypeptides
    Publication number: 20090221789
    Abstract: Crystalline formulations of therapeutic peptides, along with methods for making and using the same, are provided.
    Type: Application
    Filed: January 22, 2007
    Publication date: September 3, 2009
    Applicant: AMGEN INC.
    Inventor: Christi L. Clogston
  • Crystals of etanercept and methods of making thereof
    Patent number: 7276477
    Abstract: The present invention relates to crystalline etanercept and to methods of making crystalline etanercept; to pharmaceutical compositions comprising crystalline etanercept; and to therapeutic uses of such compositions.
    Type: Grant
    Filed: July 29, 2004
    Date of Patent: October 2, 2007
    Assignee: Amgen Inc.
    Inventors: Timothy D. Osslund, Christi L. Clogston, Shon Lee Crampton, Randal B. Bass