Patents by Inventor Christian Belmant

Christian Belmant has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Enzymatic conjugation of antibodies
    Patent number: 10675359
    Abstract: The present application relates to methods for the functionalization of immunoglobulins, in particular with drugs. Also disclosed herein are linking reagents, functionalized antibodies, pharmaceutical compositions, and method of treating disease and/or conditions.
    Type: Grant
    Filed: September 12, 2017
    Date of Patent: June 9, 2020
    Assignees: Innate Pharma, Paul Scherrer Institut
    Inventors: Patrick Dennler, Delphine Bregeon, Laurent Gauthier, François Romagné, Christian Belmant, Eliane Fischer, Roger Schibli
  • Enzymatic conjugation of polypeptides
    Patent number: 10434180
    Abstract: The present application relates to methods for the enzymatic functionalization of immunoglobulins, in particular with drugs. Also disclosed herein are linking reagents, functionalized antibodies, pharmaceutical compositions, and method of treating disease and/or conditions.
    Type: Grant
    Filed: July 19, 2016
    Date of Patent: October 8, 2019
    Assignees: INNATE PHARMA, PAUL SCHERRER INSTITUT
    Inventors: Delphine Bregeon, Patrick Dennler, Christian Belmant, Laurent Gauthier, François Romagne, Eliane Fischer, Roger Schibli
  • Screening of conjugated antibodies
    Patent number: 10132799
    Abstract: Provided is a method for the functionalization of immunoglobulins through the use of transglutaminase, including methods for screening functionalized antibodies for characteristics of interest, antibody compositions comprising a plurality of functionalized antibodies, and functionalized antibodies with rodent constant regions.
    Type: Grant
    Filed: July 10, 2013
    Date of Patent: November 20, 2018
    Assignees: INNATE PHARMA, PAUL SCHERRER INSTITUT
    Inventors: Christian Belmant, Delphine Bregeon, Patrick Dennler, Eliane Fischer, François Romagne, Roger Schibli, Laurent Gauthier
  • ENZYMATIC CONJUGATION OF ANTIBODIES
    Publication number: 20180193476
    Abstract: The present application relates to methods for the functionalization of immunoglobulins, in particular with drugs. Also disclosed herein are linking reagents, functionalized antibodies, pharmaceutical compositions, and method of treating disease and/or conditions.
    Type: Application
    Filed: September 12, 2017
    Publication date: July 12, 2018
    Inventors: Patrick Dennler, Delphine Bregeon, Laurent Gauthier, François Romagné, Christian Belmant, Eliane Fischer, Roger Schibli
  • ENZYMATIC CONJUGATION OF POLYPEPTIDES
    Publication number: 20180071402
    Abstract: The present application relates to methods for the functionalization of immunoglobulins, in particular with drugs. Also disclosed herein are linking reagents, functionalized antibodies, pharmaceutical compositions, and method of treating disease and/or conditions.
    Type: Application
    Filed: July 19, 2017
    Publication date: March 15, 2018
    Inventors: Delphine Bregeon, Patrick Dennler, Christian Belmant, Eliane Fischer, Laurent Gauthier, Francois Romagné, Roger Schibli
  • Enzymatic conjugation of antibodies
    Patent number: 9764038
    Abstract: The present application relates to methods for the functionalization of immunoglobulins, in particular with drugs. Also disclosed herein are linking reagents, functionalized antibodies, pharmaceutical compositions, and method of treating disease and/or conditions.
    Type: Grant
    Filed: December 21, 2012
    Date of Patent: September 19, 2017
    Assignees: INNATE PHARMA, PAUL SCHERRER INSTITUT
    Inventors: Patrick Dennler, Delphine Bregeon, Laurent Gauthier, François Romagné, Christian Belmant, Eliane Fischer, Roger Schibli
  • Enzymatic conjugation of polypeptides
    Patent number: 9717803
    Abstract: The present application relates to methods for the functionalization of immunoglobulins, in particular with drugs. Also disclosed herein are linking reagents, functionalized antibodies, pharmaceutical compositions, and method of treating disease and/or conditions.
    Type: Grant
    Filed: December 21, 2012
    Date of Patent: August 1, 2017
    Assignees: INNATE PHARMA, PAUL SCHERRER INSTITUT
    Inventors: Delphine Bregeon, Patrick Dennler, Christian Belmant, Eliane Fischer, Laurent Gauthier, Francois Romagné, Roger Schibli
  • ENZYMATIC CONJUGATION OF POLYPEPTIDES
    Publication number: 20160331842
    Abstract: The present application relates to methods for the enzymatic functionalization of immunoglobulins, in particular with drugs. Also disclosed herein are linking reagents, functionalized antibodies, pharmaceutical compositions, and method of treating disease and/or conditions.
    Type: Application
    Filed: July 19, 2016
    Publication date: November 17, 2016
    Inventors: Delphine Bregeon, Patrick Dennler, Christian Belmant, Laurent Gauthier, François Romagne, Eliane Fischer, Roger Schibli
  • Enzymatic conjugation of polypeptides
    Patent number: 9427478
    Abstract: The present application relates to methods for the enzymatic functionalization of immunoglobulins, in particular with drugs. Also disclosed herein are linking reagents, functionalized antibodies, pharmaceutical compositions, and method of treating disease and/or conditions.
    Type: Grant
    Filed: December 23, 2014
    Date of Patent: August 30, 2016
    Assignees: Innate Pharma, Paul Scherrer Institut
    Inventors: Delphine Bregeon, Patrick Dennler, Christian Belmant, Laurent Gauthier, François Romagne, Eliane Fischer, Roger Schibli
  • SCREENING OF CONJUGATED ANTIBODIES
    Publication number: 20150346195
    Abstract: Provided is a method for the functionalization of immunoglobulins through the use of transglutaminase, including methods for screening functionalized antibodies for characteristics of interest, antibody compositions comprising a plurality of functionalized antibodies, and functionalized antibodies with rodent constant regions.
    Type: Application
    Filed: July 10, 2013
    Publication date: December 3, 2015
    Inventors: Christian Belmant, Delphine Bregeon, Patrick Dennler, Eliane Fischer, François Romagne, Roger Schibli
  • ENZYMATIC CONJUGATION OF POLYPEPTIDES
    Publication number: 20150165064
    Abstract: The present application relates to methods for the enzymatic functionalization of immunoglobulins, in particular with drugs. Also disclosed herein are linking reagents, functionalized antibodies, pharmaceutical compositions, and method of treating disease and/or conditions.
    Type: Application
    Filed: December 23, 2014
    Publication date: June 18, 2015
    Inventors: Delphine Bregeon, Patrick Dennler, Christian Belmant, Laurent Gauthier, François Romagne, Eliane Fischer, Roger Schibli
  • ENZYMATIC CONJUGATION OF ANTIBODIES
    Publication number: 20140356385
    Abstract: The present application relates to methods for the functionalization of immunoglobulins, in particular with drugs. Also disclosed herein are linking reagents, functionalized antibodies, pharmaceutical compositions, and method of treating disease and/or conditions.
    Type: Application
    Filed: December 21, 2012
    Publication date: December 4, 2014
    Inventors: Patrick Dennler, Delphine Bregeon, Laurent Gauthier, François Romagné, Christian Belmant, Eliane Fischer, Roger Schibli
  • TLR3 Agonist Compositions
    Publication number: 20110076296
    Abstract: The present invention relates generally to the fields of medicine. More specifically, the present invention relates to improved TLR3 agonists. The present invention provides novel dsRNA such as polyAU composition useful in the treatment of TLR3 related diseases, uses and preparations thereof.
    Type: Application
    Filed: April 22, 2009
    Publication date: March 31, 2011
    Applicant: INNATE PHARMA S.A.
    Inventors: Eric Aubin, Christian Belmant, Laurent Gauthier, Yannis Morel, Carine Paturel, Delphine Bregeon
  • Class of Gamma Delta T Cells Activators and Use Thereof
    Publication number: 20100291118
    Abstract: The present invention relates to a new class of compounds having ?? T cells activating properties of Formula (I), a composition comprising these compounds and methods for regulating an immune response in a subject comprising the step of administering these compounds.
    Type: Application
    Filed: July 28, 2010
    Publication date: November 18, 2010
    Applicant: INNATE PHARMA
    Inventors: Christian Belmant, Patrice Nury
  • Compositions and Methods for Regulating an Immune Response in a Subject
    Publication number: 20100254940
    Abstract: The present invention relates to compositions an methods for regulating an immune response in a subject, particularly to treat a subject with a tumor, notably a solid tumor, or an infectious disease. Disclosed are methods of regulating the innate immunity in a subject, such as by regulating the activity of ?? T cells in a subject. Disclosed are combinations of particular agents, such as a cytokine and a ?? T cell activator, particular administration regimens and dosages can produce a remarkable expansion of ?? T cells in vivo and a remarkable increase in a subject's immune defense. The invention can be used for therapeutic purposes, to produce, regulate or facilitate an immune response in a subject.
    Type: Application
    Filed: June 28, 2010
    Publication date: October 7, 2010
    Applicant: INNATE PHARMA, S.A.
    Inventors: Francois Romagne, Helene Sicard, Jerome Tiollier, Christian Belmant
  • Class of Gamma Delta T Cells Activators and Use Thereof
    Publication number: 20100222306
    Abstract: The present invention relates to a new class of compounds having ?? T cells activating properties referred to herein as angelyl or tiglyl phosphoesters, compositions comprising any of these compounds and methods for regulating an immune response in a subject comprising the step of administering these compounds.
    Type: Application
    Filed: March 22, 2010
    Publication date: September 2, 2010
    Applicant: Innate Pharma, S.A.
    Inventor: Christian Belmant
  • Class of ?? T cells activators and use thereof
    Patent number: 7767842
    Abstract: The present invention relates to a new class of compounds having ?? T cells activating properties of Formula (I), a composition comprising these compounds and methods for regulating an immune response in a subject comprising the step of administering these compounds.
    Type: Grant
    Filed: December 2, 2004
    Date of Patent: August 3, 2010
    Assignee: Innate Pharma SA
    Inventors: Christian Belmant, Patrice Nury
  • Class of ?? T cells activators and use thereof
    Patent number: 7683045
    Abstract: The present invention relates to a new class of compounds having ?? T cells activating properties referred to herein as angelyl or tiglyl phosphoesters, compositions comprising any of these compounds and methods for regulating an immune response in a subject comprising the step of administering these compounds.
    Type: Grant
    Filed: March 21, 2006
    Date of Patent: March 23, 2010
    Assignee: Innate Pharma S.A.
    Inventor: Christian Belmant
  • Phosphohalohydrins, Process For The Production Thereof And Use Thereof
    Publication number: 20100068179
    Abstract: The invention provides compounds comprising at least one phosphohalohydrin group of the formula: where X is a halogen selected from among I, Br, Cl, R1 is selected from among —CH3 and —CH2—CH3, Cat+ is an organic or inorganic cation, and n is an integer between 2 and 20, processes for the production thereof and uses theroef, in particular therapeutic uses and for activating primate T?9?2 lymphocytes.
    Type: Application
    Filed: November 24, 2009
    Publication date: March 18, 2010
    Applicant: Institut National de la Sante et de la Recherche Medicale
    Inventors: Christian Belmant, Jean-Jacques Fournie, Marc Bonneville, Marie-Alix Peyrat
  • Phosphohalohydrins, process for the production thereof and use thereof
    Patent number: 7625879
    Abstract: The invention provides compounds comprising at least one phosphohalohydrin group of the formula: where X is a halogen selected from among I, Br, Cl, R1 is selected from among —CH3 and —CH2—CH3, Cat+ is an organic or inorganic cation, and n is an integer between 2 and 20, processes for the production thereof and uses thereof, in particular therapeutic uses and for activating primate T?9?2 lymphocytes.
    Type: Grant
    Filed: August 30, 2006
    Date of Patent: December 1, 2009
    Assignee: Institut National de la Sante et de la Recherche Medicale
    Inventors: Christian Belmant, Jean-Jacques Fournie, Marc Bonneville, Marie-Alix Peyrat