Patents by Inventor Christian Bleiholder

Christian Bleiholder has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Tandem ion mobility spectrometer
    Patent number: 10794861
    Abstract: The invention proposes a methods and devices for tandem ion mobility spectrometry using at least one TIMS analyzers (TIMS=trapping ion mobility spectrometry), in particular in the field of structural biology.
    Type: Grant
    Filed: January 30, 2019
    Date of Patent: October 6, 2020
    Inventors: Melvin Andrew Park, Mark Ridgeway, Christian Bleiholder, Fanny Caroline Liu
  • Determining molecular and molecular assembly structures from a momentum transfer cross section distribution
    Patent number: 10605773
    Abstract: Provided are systems and methods for de novo determinations of molecular structures or assemblies, including biologically relevant protein structures or assemblies, from IMS-MS data alone. The systems and methods perform a comprehensive conformational analysis of a molecule or molecular assembly, predict IMS-MS spectra for the molecule or molecular assembly, and report structures that best explain experimental spectra for the molecule or molecular assembly.
    Type: Grant
    Filed: June 6, 2017
    Date of Patent: March 31, 2020
    Assignee: The Florida State University Research Foundation, Inc.
    Inventor: Christian Bleiholder
  • Determining Molecular and Molecular Assembly Structures from a Momentum Transfer Cross Section Distribution
    Publication number: 20190302054
    Abstract: Provided are systems and methods for de novo determinations of molecular structures or assemblies, including biologically relevant protein structures or assemblies, from IMS-MS data alone. The systems and methods perform a comprehensive conformational analysis of a molecule or molecular assembly, predict IMS-MS spectra for the molecule or molecular assembly, and report structures that best explain experimental spectra for the molecule or molecular assembly.
    Type: Application
    Filed: June 6, 2017
    Publication date: October 3, 2019
    Inventor: Christian Bleiholder
  • TANDEM ION MOBILITY SPECTROMETER
    Publication number: 20190265195
    Abstract: The invention proposes a methods and devices for tandem ion mobility spectrometry using at least one TIMS analyzers (TIMS=trapping ion mobility spectrometry), in particular in the field of structural biology.
    Type: Application
    Filed: January 30, 2019
    Publication date: August 29, 2019
    Inventors: Melvin Andrew PARK, Mark RIDGEWAY, Christian BLEIHOLDER, Fanny Caroline LIU
  • Approximation algorithm for solving a momentum transfer cross section
    Patent number: 9829466
    Abstract: The present invention comprises a method for automated, high throughput molecular identification of macromolecular organic compounds. The method may provide an approximate solution to a momentum transfer cross section of an analyte in a buffer gas as measured by an ion mobility spectrometer that has low computational demand, has a high level of accuracy, and is adaptable for a variety of drift gases.
    Type: Grant
    Filed: August 12, 2016
    Date of Patent: November 28, 2017
    Assignee: Florida State University Research Foundation, Inc.
    Inventor: Christian Bleiholder
  • APPROXIMATION ALGORITHM FOR SOLVING A MOMENTUM TRANSFER CROSS SECTION
    Publication number: 20160349212
    Abstract: The present invention comprises a method for automated, high throughput molecular identification of macromolecular organic compounds. The method may provide an approximate solution to a momentum transfer cross section of an analyte in a buffer gas as measured by an ion mobility spectrometer that has low computational demand, has a high level of accuracy, and is adaptable for a variety of drift gases.
    Type: Application
    Filed: August 12, 2016
    Publication date: December 1, 2016
    Inventor: Christian Bleiholder