Patents by Inventor Christian Brander

Christian Brander has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Publication number: 20250180558
    Abstract: The present invention relates to a method for assaying antigen-specific T-cell responses through boosted flow cytometry and boosted ELISPOT technologies that are based on the use of specific combinations of monoclonal antibodies to stain simultaneously cytokines that in their combination identify specific T-cell polarization profiles. The method allows the identification of Tfc CD8+ T cell responses unrecognized so far.
    Type: Application
    Filed: March 9, 2023
    Publication date: June 5, 2025
    Inventors: Marta RUIZ RIOL, Christian BRANDER-SILVA, Alex OLVERA VAN DER STOEP, Luis ROMERO MARTÍN
  • Patent number: 11919926
    Abstract: The present invention relates to novel immunogens based on overlapping peptides (OLPs) and peptides derived therefrom useful for the prevention and treatment of AIDS and its related opportunistic diseases. The invention also relates to isolated nucleic acids, vectors and host cells expressing these immunogens as well as vaccines including said immunogens.
    Type: Grant
    Filed: April 29, 2021
    Date of Patent: March 5, 2024
    Assignees: ESTEVE PHARMACEUTICALS, S.A., FUNDACIO PRIVADA INSTITUT DE RECERCA DE LA SIDA—CAIXA
    Inventors: Christian Brander, Beatriz Mothe Pujadas, Anuska Llano
  • Patent number: 11666651
    Abstract: The present invention relates to immunogenic therapies for the treatment or prevention of a human immunodeficiency virus (HIV) infection or a disease associated with an HIV infection.
    Type: Grant
    Filed: November 12, 2020
    Date of Patent: June 6, 2023
    Assignee: AELIX Therapeutics, S.L.
    Inventors: Christian Brander, Beatriz Mothe-Pujadas
  • Publication number: 20220226459
    Abstract: The present invention relates to immunogenic therapies for the treatment or prevention of a human immunodeficiency virus (HIV) infection or a disease associated with an HIV infection.
    Type: Application
    Filed: May 21, 2020
    Publication date: July 21, 2022
    Inventors: CHRISTIAN BRANDER, BEATRIZ MOTHE PUJADAS, IAN MCGOWAN
  • Publication number: 20220218711
    Abstract: The present disclosure describes methods, compositions, and kits related to the combination of a TLR7 modulating compound and an HIV vaccine. The combination can be used in a method of treating or preventing an HIV infection in a human.
    Type: Application
    Filed: May 21, 2020
    Publication date: July 14, 2022
    Inventors: Romas Geleziunas, Devi Sengupta, Christian Brander, Beatriz Mothe Pujadas, Ian McGowan
  • Patent number: 11325946
    Abstract: The present invention relates to novel immunogens based on overlapping peptides (OLPs) and peptides derived therefrom useful for the prevention and treatment of AIDS and its related opportunistic diseases. The invention also relates to isolated nucleic acids, vectors and host cells expressing these immunogens as well as vaccines including said immunogens.
    Type: Grant
    Filed: May 3, 2018
    Date of Patent: May 10, 2022
    Assignees: LABORATORIOS DEL DR. ESTEVE S.A., FUNDACIÓ PRIVADA INSTITUT DE RECERCA DE LA SIDE—CAIXA
    Inventors: Christian Brander, Beatriz Mothe Pujadas, Anuska Llano
  • Publication number: 20210246172
    Abstract: The present invention relates to novel immunogens based on overlapping peptides (OLPs) and peptides derived therefrom useful for the prevention and treatment of AIDS and its related opportunistic diseases. The invention also relates to isolated nucleic acids, vectors and host cells expressing these immunogens as well as vaccines including said immunogens.
    Type: Application
    Filed: April 29, 2021
    Publication date: August 12, 2021
    Inventors: Christian BRANDER, Beatriz Mothe PUJADAS, Anuska LLANO
  • Publication number: 20210145961
    Abstract: The present invention relates to immunogenic therapies for the treatment or prevention of a human immunodeficiency virus (HIV) infection or a disease associated with an HIV infection.
    Type: Application
    Filed: November 12, 2020
    Publication date: May 20, 2021
    Inventors: Christian BRANDER, Beatriz MOTHE-PUJADAS
  • Patent number: 10815278
    Abstract: The present invention relates to novel immunogens based on overlapping peptides (OLPs) and peptides derived therefrom useful for the prevention and treatment of AIDS and its related opportunistic diseases. The invention also relates to isolated nucleic acids, vectors and host cells expressing these immunogens as well as vaccines including said immunogens.
    Type: Grant
    Filed: September 28, 2017
    Date of Patent: October 27, 2020
    Assignees: Laboratorios del Dr. Esteve S.A., Fundació Privada Institut de Recerca de La Sida—Caixa
    Inventors: Christian Brander, Beatriz Mothe Pujadas, Anuska Llano
  • Publication number: 20190055289
    Abstract: The present invention relates to novel immunogens based on overlapping peptides (OLPs) and peptides derived therefrom useful for the prevention and treatment of AIDS and its related opportunistic diseases. The invention also relates to isolated nucleic acids, vectors and host cells expressing these immunogens as well as vaccines including said immunogens.
    Type: Application
    Filed: May 3, 2018
    Publication date: February 21, 2019
    Inventors: Christian BRANDER, Beatriz MOTHE PUJADAS, Anuska LLANO
  • Publication number: 20180170971
    Abstract: The present invention relates to novel immunogens based on overlapping peptides (OLPs) and peptides derived therefrom useful for the prevention and treatment of AIDS and its related opportunistic diseases. The invention also relates to isolated nucleic acids, vectors and host cells expressing these immunogens as well as vaccines including said immunogens.
    Type: Application
    Filed: September 28, 2017
    Publication date: June 21, 2018
    Inventors: Christian BRANDER, Beatriz MOTHE PUJADAS, Anuska LLANO
  • Patent number: 9988425
    Abstract: The present invention relates to novel immunogens based on overlapping peptides (OLPs) and peptides derived therefrom useful for the prevention and treatment of AIDS and its related opportunistic diseases. The invention also relates to isolated nucleic acids, vectors and host cells expressing these immunogens as well as vaccines including the immunogens.
    Type: Grant
    Filed: January 28, 2013
    Date of Patent: June 5, 2018
    Assignees: Laboratories Del Dr. Esteve S.A., Fundació Privada Institut De Recerca De La Sida—CAIXA
    Inventors: Christian Brander, Beatriz Mothe Pujadas, Anuska Llano
  • Publication number: 20170202950
    Abstract: The invention relates to peptides comprising part or all of a conserved element within a Center-of-Tree (COT) sequence derived from a family of polypeptides encoded by naturally occurring variants of HIV. The invention also relates to immunogenic compositions and vaccines comprising said peptides. The invention also relates to methods for the identification of HIV controller patients based on the detection of the T cells of the patient to mount a cytotoxic T cell response against said peptides and to methods for the identification of immunogenic peptides within a family of variant polypeptides.
    Type: Application
    Filed: March 20, 2017
    Publication date: July 20, 2017
    Inventors: Beatriz MOTHE PUJADAS, Christian BRANDER, James I. MULLINS
  • Patent number: 9709577
    Abstract: The invention relates to a method and a diagnostic kit for monitoring HIV specific T cell responses and identifying subjects capable of controlling HIV progression or preventing HIV infection altogether. The method is based on the combined use of boosted flow cytometry and toggle peptides and can cover a large set of effector functions. The method is also suitable to detect T cell responses of any desirable cytokine or combination of cytokines to any pathogen.
    Type: Grant
    Filed: March 22, 2013
    Date of Patent: July 18, 2017
    Assignees: LABORATORIOS DEL DR. ESTEVE S.A., FUNDACIO PRIVADA INSTITUT DE RECERCA DE LA SIDA—CAIXA, INSTITUCIÓ CATALANA DE RECERCA I ESTUDIOS AVANÇATS
    Inventors: Marta Ruiz Riol, Christian Brander, Javier Ibarrondo
  • Publication number: 20150057175
    Abstract: The invention relates to a method and a diagnostic kit for monitoring HIV specific T cell responses and identifying subjects capable of controlling HIV progression or preventing HIV infection altogether. The method is based on the combined use of boosted flow cytometry and toggle peptides and can cover a vastly larger set of effector functions than standard assays.
    Type: Application
    Filed: March 22, 2013
    Publication date: February 26, 2015
    Inventors: Marta Ruiz Riol, Christian Brander, Javier Ibarrondo
  • Publication number: 20150050310
    Abstract: The present invention relates to novel immunogens based on overlapping peptides (OLPs) and peptides derived therefrom useful for the prevention and treatment of AIDS and its related opportunistic diseases. The invention also relates to isolated nucleic acids, vectors and host cells expressing these immunogens as well as vaccines including the immunogens.
    Type: Application
    Filed: January 28, 2013
    Publication date: February 19, 2015
    Inventors: Christian Brander, Beatriz Mothe Pujadas, Anuska Llano
  • Publication number: 20130302364
    Abstract: The invention relates to peptides comprising part or all of a conserved element within a Center-of-Tree (COT) sequence derived from a family of polypeptides encoded by naturally occurring variants of HIV. The invention also relates to immunogenic compositions and vaccines comprising said peptides. The invention also relates to methods for the identification of HIV controller patients based on the detection of the T cells of the patient to mount a cytotoxic T cell response against said peptides and to methods for the identification of immunogenic peptides within a family of variant polypeptides.
    Type: Application
    Filed: November 10, 2011
    Publication date: November 14, 2013
    Applicants: LABORATORIOS DEL DR. ESTEVE, S.A., UNIVERSITY OF WASHINGTON, INSTITUCIÓ CATALANA DE RECERCA I ESTUDIS AVANÇATS, FUNDACIÓ PRIVADA INSTITUT DE RECERCA DE LA SIDA - CAIXA
    Inventors: Beatriz Mothe Pujadas, Christian Brander, James I. Mullins