Patents by Inventor Christian CAPITINI

Christian CAPITINI has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • T CELL SPECIFIC BIOMARKERS FOR PREDICTING GRAFT-VS-HOST DISEASE AND HEMATOPOIETIC MALIGNANCY RELAPSE FOLLOWING HEMATOPOIETIC STEM CELL TRANSPLANTATION AND TREATMENT THEREOF
    Publication number: 20230221318
    Abstract: The present disclosure generally relates to methods for diagnosing, predicting and treating graft-vs-host disease and/or relapse of a hematologic malignancy following hematopoietic stem cell transplantation based on T-cell specific biomarkers.
    Type: Application
    Filed: January 6, 2023
    Publication date: July 13, 2023
    Inventors: Nicholas Hess, Christian Capitini, Kalyan Nadiminti, Peiman Hematti, Jenny Gumperz
  • LPS priming of stromal cells to generate LPS-specific exosome educated macrophages
    Patent number: 11499730
    Abstract: The disclosure relates to an ex vivo generated population of educated macrophages specific to LPS and methods of making and using such macrophages.
    Type: Grant
    Filed: February 12, 2019
    Date of Patent: November 15, 2022
    Assignee: WISCONSIN ALUMNI RESEARCH FOUNDATION
    Inventors: Peiman Hematti, John A. Kink, Christian Capitini
  • LPS Priming of Stromal Cells to Generate LPS-Specific Exosome Educated Macrophages
    Publication number: 20220349599
    Abstract: The disclosure relates to an ex vivo generated population of educated macrophages specific to LPS and methods of making and using such macrophages.
    Type: Application
    Filed: July 12, 2022
    Publication date: November 3, 2022
    Inventors: Peiman Hematti, John A. Kink, Christian Capitini
  • Use of Toll-Like Receptor 4 Agonists to Treat Inflammation and Tissue Injury
    Publication number: 20220127579
    Abstract: The disclosure relates to populations of educated macrophages and monocytes generated ex vivo or in vivo, and methods of making and using the same using lipid A aminoalkylglucosaminide phosphate molecules, such as CRX molecules or extracellular vesicles (EVs) from mesenchymal stromal cells (MSC) stimulated with CRX molecules. Also described are EVs and methods for making and using the same from MSCs exposed to CRX.
    Type: Application
    Filed: October 22, 2021
    Publication date: April 28, 2022
    Inventors: Peiman HEMATTI, John KINK, Christian CAPITINI, Matthew FORSBERG, Nicholas HESS, Zachary ROSENKRANS, Reinier HERNANDEZ