Patents by Inventor Christian Diolez

Christian Diolez has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Process for preparing 21 acyloxy-.DELTA.4,9(11),16 pregnatrienes 3-20-dione
    Patent number: 5401864
    Abstract: A process for the preparation of a compound of the formula ##STR1## wherein R.sub.1 is acyl of 1 to 8 carbon atoms, by reducing an intermediary to form an alcohol, oxidizing the alcohol to form an aidehyde, which is subjected to the action of an acyloxylation agent.
    Type: Grant
    Filed: October 29, 1993
    Date of Patent: March 28, 1995
    Assignee: Roussel-Uclaf
    Inventors: Francis Brion, Jean Buendia, Christian Diolez, Michel Vivat
  • Intermediate steroid compounds
    Patent number: 5401840
    Abstract: Novel compounds of the formula ##STR1## wherein either K' is oxygen or a K, a protective group of the oxo of the formula ##STR2## wherein n is 2 or 3, the 17-position dotted line is a bond, R.sub.a and R.sub.b are individually selected from the group consisting of hydrogen, hydroxy, alkyl and alkoxy of 1 to 4 carbon atoms or K' is an oxygen, the 17-position dotted line is an epoxy and R.sub.a and R.sub.b have the meaning indicated above which are useful intermediates for the preparation of hydrocortisone.
    Type: Grant
    Filed: August 12, 1993
    Date of Patent: March 28, 1995
    Assignee: Roussel-Uclaf
    Inventors: Francis Brion, Jean Buendia, Christian Diolez, Michel Vivat
  • 4,9(11),17(20)-pregnatriene-3-ones
    Patent number: 5294704
    Abstract: A process for the production of a compound of the formula ##STR1## wherein R is an acyl group of 1 to 8 carbon atoms. The compound is formed through an intermediate compound of the formula ##STR2## wherein R.sub.1 is selected from the group consisting of methyl, phenyl, tolyl, and xylyl and wherein K is a protective group selected from the group consisting of ##STR3## in which n is 2 or 3 and the wavy line means that the group SO.sub.2 --R.sub.1 may have either isomeric form or are mixtures thereof.
    Type: Grant
    Filed: November 4, 1992
    Date of Patent: March 15, 1994
    Assignee: Roussel-Uclaf
    Inventors: Francis Brion, Jean Buendia, Christian Diolez, Michel Vivat
  • Process for the preparation of hydrocortisone
    Patent number: 5260463
    Abstract: An improved process for the preparation of hydrocortisone and novel intermediates which avoids an 11-hydroxylation step and results in improved yields.
    Type: Grant
    Filed: August 25, 1992
    Date of Patent: November 9, 1993
    Assignee: ROUSSEL-UCLAF
    Inventors: Francis Brion, Jean Buendia, Christian Diolez, Michel Vivat
  • .DELTA..sup.4,9(11),17(20) -pregnatriene-3-ones
    Patent number: 5187273
    Abstract: A compound of the formula ##STR1## wherein Hal is chlorine or bromine, R is selected from the group consisting of alkyl of 1 to 6 carbon atoms, aralkyl of 7 to 15 carbon atoms and a silylated group, K is a protective group selected from the group consisting of ##STR2## n is 2 or 3 and the wavy lines mean the groups may have either isomer form or are mixtures thereof which are intermediates for .DELTA..sup.4,9(11),16 -pregnatriene-3-ones.
    Type: Grant
    Filed: May 18, 1992
    Date of Patent: February 16, 1993
    Assignee: Roussel Uclaf
    Inventors: Francis Brion, Jean Buendia, Christian Diolez, Michel Vivat