Patents by Inventor Christian Fledelius

Christian Fledelius has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Insulin derivatives and the medical uses hereof
    Patent number: 11352406
    Abstract: The present invention is in the therapeutic fields of drugs for medical conditions relating to diabetes. More specifically the invention relates to novel acylated derivatives of human insulin analogues. The invention also provides pharmaceutical compositions comprising such insulin derivatives, and relates to the use of such derivatives for the treatment or prevention of medical conditions relating to diabetes.
    Type: Grant
    Filed: August 24, 2016
    Date of Patent: June 7, 2022
    Assignee: Novo Nordisk A/S
    Inventors: Peter Madsen, Anthony Murray, Martin Muenzel, Claudia Ulrich Hjoerringgaard, Susanne Hostrup, Tine Glendorf, Mathias Norrman, Christian Fledelius
  • NOVEL INSULIN DERIVATIVES
    Publication number: 20210024604
    Abstract: The novel insulin derivates delivers, after administration to humans, insulin as a function of the glucose concentration in the tissue.
    Type: Application
    Filed: October 7, 2020
    Publication date: January 28, 2021
    Inventors: Thomas Hoeg-Jensen, Palle Jakobsen, Ulrich Sensfuss, Christian Fledelius, Ulla Ribel-Madsen
  • Novel Insulin Derivatives and the Medical Uses Hereof
    Publication number: 20200283493
    Abstract: The present invention is in the therapeutic fields of drugs for medical conditions relating to diabetes. More specifically the invention relates to novel acylated derivatives of human insulin analogues. The invention also provides pharmaceutical compositions comprising such insulin derivatives, and relates to the use of such derivatives for the treatment or prevention of medical conditions relating to diabetes.
    Type: Application
    Filed: March 25, 2020
    Publication date: September 10, 2020
    Inventors: Peter Madsen, Martin Muenzel, Claudia Ulrich Hjoerringgaard, Susanne Hostrup, Tine Glendorf, Mathias Norrman, Christian Fledelius
  • INSULIN DERIVATIVES
    Publication number: 20200172593
    Abstract: The novel insulin derivates delivers, after administration to humans, insulin as a function of the glucose concentration in the tissue.
    Type: Application
    Filed: February 7, 2020
    Publication date: June 4, 2020
    Inventors: Thomas Hoeg-Jensen, Palle Jakobsen, Ulrich Sensfuss, Christian Fledelius, Ulla Ribel-Madsen
  • Novel Insulin Derivatives and the Medical Uses Hereof
    Publication number: 20190010206
    Abstract: The present invention is in the therapeutic fields of drugs for medical conditions relating to diabetes. More specifically the invention relates to novel acylated derivatives of human insulin analogues. The invention also provides pharmaceutical compositions comprising such insulin derivatives, and relates to the use of such derivatives for the treatment or prevention of medical conditions relating to diabetes.
    Type: Application
    Filed: August 24, 2016
    Publication date: January 10, 2019
    Inventors: Peter Madsen, Martin Muenzel, Claudia Ulrich Hjoerringgaard, Susanne Hostrup, Tine Glendorf, Mathias Norrman, Christian Fledelius
  • NOVEL INSULIN DERIVATIVES
    Publication number: 20180371045
    Abstract: The novel insulin derivates delivers, after administration to humans, insulin as a function of the glucose concentration in the tissue.
    Type: Application
    Filed: July 20, 2018
    Publication date: December 27, 2018
    Inventors: Thomas Hoeg-Jensen, Palle Jakobsen, Ulrich Sensfuss, Christian Fledelius, Ulla Ribel-Madsen
  • Novel Insulin Derivatives and the Medical Uses Hereof
    Publication number: 20180305431
    Abstract: The present invention is in the therapeutic fields of drugs for medical conditions relating to diabetes. More specifically the invention relates to novel acylated derivatives of human insulin analogues. The invention also provides pharmaceutical compositions comprising such insulin derivatives, and relates to the use of such derivatives for the treatment or prevention of medical conditions relating to diabetes.
    Type: Application
    Filed: August 24, 2016
    Publication date: October 25, 2018
    Inventors: Peter Madsen, Anthony Murray, Martin Muenzel, Claudia Ulrich Hjoerringgaard, Susanne Hostrup, Tine Glendorf, Mathias Norrman, Christian Fledelius
  • Novel Insulin Derivatives and the Medical Uses Hereof
    Publication number: 20180244743
    Abstract: The present invention is in the therapeutic fields of drugs for medical conditions relating to diabetes. More specifically the invention relates to novel acylated derivatives of human insulin analogues. The invention also provides pharmaceutical compositions comprising such insulin derivatives, and relates to the use of such derivatives for the treatment or prevention of medical conditions relating to diabetes.
    Type: Application
    Filed: August 24, 2016
    Publication date: August 30, 2018
    Inventors: Peter Madsen, Claudia Ulrich Hjoerringgaard, Martin Muenzel, Susanne Hostrup, Christian Fledelius
  • Insulin derivatives and the medical uses hereof
    Patent number: 10040839
    Abstract: The present invention is in the therapeutic fields of drugs for medical conditions relating to diabetes. More specifically the invention relates to novel acylated derivatives of human insulin analogues. The invention also provides pharmaceutical compositions comprising such insulin derivatives, and relates to the use of such derivatives for the treatment or prevention of medical conditions relating to diabetes.
    Type: Grant
    Filed: February 26, 2015
    Date of Patent: August 7, 2018
    Assignee: Novo Nordisk A/S
    Inventors: Peter Madsen, Susanne Hostrup, Martin Muenzel, Thomas Boerglum Kjeldsen, Claudia Ulrich Hjoerringgaard, Christian Fledelius
  • Novel Insulin Derivatives and the Medical Uses Hereof
    Publication number: 20170008945
    Abstract: The present invention is in the therapeutic fields of drugs for medical conditions relating to diabetes. More specifically the invention relates to novel acylated derivatives of human insulin analogues. The invention also provides pharmaceutical compositions comprising such insulin derivatives, and relates to the use of such derivatives for the treatment or prevention of medical conditions relating to diabetes.
    Type: Application
    Filed: February 26, 2015
    Publication date: January 12, 2017
    Inventors: Peter Madsen, Susanne Hostrup, Martin Muenzel, Thomas Boerglum Kjeldsen, Claudia Ulrich Hjoerringgaard, Christian Fledelius
  • Novel Insulin Derivatives
    Publication number: 20160229902
    Abstract: The novel insulin derivates delivers, after administration to humans, insulin as a function of the glucose concentration in the tissue.
    Type: Application
    Filed: April 18, 2016
    Publication date: August 11, 2016
    Inventors: Thomas Hoeg-Jensen, Palle Jakobsen, Ulrich Sensfuss, Christian Fledelius, Ulla Ribel-Madsen
  • INSULIN DERIVATIVES
    Publication number: 20120184487
    Abstract: The novel insulin derivates delivers, after administration to humans, insulin as a function of the glucose concentration in the tissue.
    Type: Application
    Filed: June 29, 2010
    Publication date: July 19, 2012
    Applicant: Novo Nordisk A/S
    Inventors: Thomas Hoeg-Jensen, Palle Jakobsen, Ulrich Sensfuss, Christian Fledelius, Ulla Ribel-Madsen
  • Assaying fragments of collagen in body fluids
    Patent number: 6420125
    Abstract: This invention relates, in part, to a method of measuring the rate of degradation of collagen is disclosed which comprises determining the amount in a body fluid of one or more fragments of collagen having an amino acid sequence comprising isoaspartic acid. The invention also relates to an immunological binding partner that specifically binds to an amino acid sequence of type II collagen containing an isoaspartic acid residue. The invention further relates to a synthetic peptide having an amino acid sequence of type II collagen that contains an isoaspartic acid residue.
    Type: Grant
    Filed: August 21, 2000
    Date of Patent: July 16, 2002
    Assignee: Osteometer Biotech A/S
    Inventors: Christian Fledelius, Martin Bonde, Per Qvist
  • Assaying D-amino acids in body fluids
    Patent number: 6300083
    Abstract: The rate of degradation in vivo of a body protein is determined by measuring the amount of a D-amino acid containing fragment of the protein in a body fluid using an antibody capable of discriminating between the D-amino acid containing fragment and its L-amino acid containing analogue.
    Type: Grant
    Filed: January 10, 2000
    Date of Patent: October 9, 2001
    Assignee: Osteometer Biotech A/S
    Inventors: Christian Fledelius, Paul Cloos, Per Qvist
  • Assaying protein fragments in body fluids
    Patent number: 6107047
    Abstract: Degradation of body proteins such as bone collagen is studied by detecting in body fluids isomerized peptide fragments of said proteins in which peptide bonding to the .alpha.-carboxylic acid group of aspartic acid or asparagine has become isomerized to an amide bond to the side chain carboxylic acid group of aspartic acid. Antibodies specific for the isomerized peptide sequences are used in assays.
    Type: Grant
    Filed: September 22, 1997
    Date of Patent: August 22, 2000
    Assignee: Osteometer Biotech A/S
    Inventors: Christian Fledelius, Martin Bonde, Per Qvist