Abstract: The present invention relates to a microbioreactor comprising a sample support (7) for holding cells; a bypass (3) with a capillary opening for feeding test reagent and/or for aeration and ventilation of the microbioreactor; a pump module (5) for perfusion of the microbioreactor with test reagent and/or gas feeding and purging of the microbioreactor; a transparent viewing window (2); and fluid channels (4) that form a circuit. The invention further relates to a bioreactor-microtiter plate comprising a plurality of such microbioreactors.

Abstract: The invention relates to a partially active microfluidic system for cell cultivation comprising a multiwell system (4) with multiple wells (17) and cavities formed therein that hold cells. Each cavity (11) is formed by at least one inlay (3) comprising an opening (1) that does not open up directly into the cavity (11), but rather into a space (17) surrounding the cavity, wherein the medium present in the surrounding space communicates with the medium contained in the cavity (11) by way of a sieve structure in the inlay. The invention is suitable in particular for 3D cell cultivation.