Abstract: A hose holder for holding a hose inside an opening in a structure is disclosed. The hose holder includes a hose engagement portion configured to surround at least a portion of a hose and perimeter engaging portions joined to the hose engagement portion for engaging the portions of the structure adjacent to the opening into which the hose is inserted and holding a hose within the opening.

Abstract: The present invention encompasses compounds of formula (I) wherein R1a, R1b, R2a, R2b, Z, R3 to R5, A, p, U, V, W, L and E have the meanings given in the claims and specification, their use as inhibitors of mutant Ras family proteins, pharmaceutical compositions and preparations containing such compounds and their use as medicaments/medical uses, especially as agents for treatment and/or prevention of oncological diseases.

Abstract: The breastfeeding device comprises a suction assembly that attaches to one of the mother's breasts, a pump assembly that provides suction to express milk from the mother's breast and collect it in a reservoir, a pacifier that allow a baby to feed on collected breast milk, and interconnecting flexible tubing. In some embodiments, the breastfeeding device may also comprise a breastfeeding garment which may allow the mother to use the suction assembly while wearing clothing and which may help to hold the suction assembly in place. A shutoff valve on the outlet of the pump assembly may allow the pacifier and associated tubing to be disconnected without loss of breast milk when the baby is not feeding.