Patents by Inventor Christian Hodneland

Christian Hodneland has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Polypeptide Immobilization
    Publication number: 20150369816
    Abstract: The present invention provides a method, comprising (a) providing a reactant ligand attached to a substrate; (b) contacting the substrate with a fusion polypeptide, said fusion polypeptide comprising a capture polypeptide fused to a display polypeptide under conditions such that said reactant ligand covalently binds to said capture polypeptide; and (c) analyzing said display polypeptide.
    Type: Application
    Filed: June 26, 2015
    Publication date: December 24, 2015
    Inventors: Milan MRKSICH, Christian HODNELAND
  • Polypeptide immobilization
    Patent number: 9074300
    Abstract: The present invention provides a method, comprising (a) providing a reactant ligand attached to a substrate; (b) contacting the substrate with a fusion polypeptide, said fusion polypeptide comprising a capture polypeptide fused to a display polypeptide under conditions such that said reactant ligand covalently binds to said capture polypeptide; and (c) analyzing said display polypeptide.
    Type: Grant
    Filed: February 4, 2011
    Date of Patent: July 7, 2015
    Assignee: The University of Chicago
    Inventors: Milan Mrksich, Christian Hodneland
  • POLYPEPTIDE IMMOBILIZATION
    Publication number: 20120142547
    Abstract: The present invention provides a method, comprising (a) providing a reactant ligand attached to a substrate; (b) contacting the substrate with a fusion polypeptide, said fusion polypeptide comprising a capture polypeptide fused to a display polypeptide under conditions such that said reactant ligand covalently binds to said capture polypeptide; and (c) analyzing said display polypeptide.
    Type: Application
    Filed: February 4, 2011
    Publication date: June 7, 2012
    Inventors: Milan Mrksich, Christian Hodneland
  • Polypeptide immobilization
    Patent number: 7888055
    Abstract: A substrate comprises a surface, and a plurality of moieties, on at least a portion of the surface. The moieties are moieties of formula: Surf-L-Q-T, where -T comprises a reactant ligand, and Surf- designates where the moiety attaches to the surface. The substrate can be made into a protein chip by the reaction of a reactant ligand and a fusion polypeptide, where the fusion polypeptide includes a capture polypeptide moiety which corresponds to the reactant ligand.
    Type: Grant
    Filed: December 21, 2006
    Date of Patent: February 15, 2011
    Assignee: The University of Chicago
    Inventors: Milan Mrksich, Christian Hodneland
  • Immobilization of biological molecules onto surfaces coated with monolayers
    Publication number: 20090325262
    Abstract: The present invention provides an article for immobilizing functional organic biomolecules through a covalent bond to a thiolate monolayer on a coinage metal surface. Also provided are methods for making the article and method for the immobilization of functional organic biomolecules on the article. The thiolate monolayer contains two moieties, one having an inert group that is resistant to reacting with biomolecules and one having a covalent bond forming group that reacts with the functional organic biomolecule to covalently immobilize it on the monolayer.
    Type: Application
    Filed: April 18, 2008
    Publication date: December 31, 2009
    Inventors: Christian Hodneland, Stewart Campbell, David Duffy, Melina Agosto, Evelyn Wang
  • Polypeptide immobilization
    Publication number: 20080064606
    Abstract: A substrate comprises a surface, and a plurality of moieties, on at least a portion of the surface. The moieties are moieties of formula: Surf-L-Q-T, where -T comprises a reactant ligand, and Surf- designates where the moiety attaches to the surface. The substrate can be made into a protein chip by the reaction of a reactant ligand and a fusion polypeptide, where the fusion polypeptide includes a capture polypeptide moiety which corresponds to the reactant ligand.
    Type: Application
    Filed: December 21, 2006
    Publication date: March 13, 2008
    Inventors: Milan Mrksich, Christian Hodneland
  • Polypeptide immobilization
    Patent number: 7172905
    Abstract: A substrate comprises a surface, and a plurality of moieties, on at least a portion of the surface. The moieties are moieties of formula: Surf-L—Q—T, where —T comprises a reactant ligand, and Surf- designates where the moiety attaches to the surface. The substrate can be made into a protein chip by the reaction of a reactant ligand and a fusion polypeptide, where the fusion polypeptide includes a capture polypeptide moiety which corresponds to the reactant ligand.
    Type: Grant
    Filed: August 7, 2001
    Date of Patent: February 6, 2007
    Assignee: The University of Chicago
    Inventors: Milan Mrksich, Christian Hodneland
  • Controlled release composition
    Patent number: 6764768
    Abstract: An alkanethiol of formula (1): HS—L—Q1—T—Q2—M—G—Z  (1), may for a SAM. Under application of a potential to the surface, the leaving group —Z is released.
    Type: Grant
    Filed: February 28, 2001
    Date of Patent: July 20, 2004
    Assignee: Arch Development Corporation
    Inventors: Milan Mrksich, Christian Hodneland
  • Polypeptide immobilization
    Publication number: 20030119054
    Abstract: A substrate comprises a surface, and a plurality of moieties, on at least a portion of the surface.
    Type: Application
    Filed: August 7, 2001
    Publication date: June 26, 2003
    Inventors: Milan Mrksich, Christian Hodneland
  • Controlled release composition
    Publication number: 20020119305
    Abstract: An alkanethiol of formula (1):
    Type: Application
    Filed: February 28, 2001
    Publication date: August 29, 2002
    Inventors: Milan Mrksich, Christian Hodneland