Abstract: A valve assembly comprises a fastening element and at least one valve configured to be removably mounted to the fastening element. The fastening element includes a fastening body and a plurality of fastening islands. The fastening element has an elongated shape along a direction of elongation and is configured to be fastened in an automotive vehicle by at rear face of the fastening body. The fastening body comprises a plurality of openings aligned along the direction of elongation, each fastening island being housed in a respective through opening and is mechanically coupled to the fastening body by flexible means. The valve includes a casing, and is configured to be removably mounted in a mounted position to a respective fastening island at a front face thereof by attachment means configured to mount the valve to the fastening island according to a sliding movement and/or a rotating movement.

Abstract: An elevator car for transporting people and goods and having a floor panel, at least three side panels, and a roof panel together forming a door opening. The floor panel, at least one side panel, and the roof panel are unitarily formed of a thermoplastic synthetic resin. A force-spreading element substantially more rigid than the panels is fixed in or on an face of one of the side panels or the roof panel. A hoist system for the car is fixed by fasteners to the load-spreading element.

Abstract: A lock for holding a first part to a second part comprises a holding body with a receptacle for receiving a protruding part of the second part. The holding body has a wall that borders the receptacle and a locking element, the locking element having a protrusion, whereby the locking element has a first position, whereby in the first position the protrusion is in a locking position, whereby in the locking position the protrusion protrudes from the wall into the receptacle by a first amount and the locking element has a second position, whereby in the second position the protrusion is in a release position, whereby in the release position the protrusion either protrudes from the wall into the receptacle by a second amount, whereby the second amount is smaller than the first amount, or the protrusion does not protrude from the wall.

Abstract: A lock for holding a first part to a second part comprises a holding body with a receptacle for receiving a protruding part of the second part. The holding body having has a wall that borders the receptacle and a locking element, the locking element having a protrusion, whereby the locking element has a first position, whereby in the first position the protrusion is in a locking position, whereby in the locking position the protrusion protrudes from the wall into the receptacle by a first amount and the locking element has a second position, whereby in the second position the protrusion is in a release position, whereby in the release position the protrusion either protrudes from the wall into the receptacle by a second amount, whereby the second amount is smaller than the first amount, or the protrusion does not protrude from the wall.

Abstract: A clip with a head and a shank extending along a longitudinal axis from the head in which ribs are provided, each rib extending from a base of the respective rib on the shank to an end of the respective rib radially spaced from the base of the respective rib, a rib is connected in sections directly to the head, a rib has an elastic arm which protrudes from the respective rib, a rib has a side extending between the rib base and the rib end, wherein the elastic arm of this rib protrudes from this side of the rib, an elastic arm having first and second sections, the first section being connected at one end to the rib and at its other end to the second section, the second section extending in a different direction from the first section, the first section is connected directly to the head.

Abstract: A method for detecting p217+tau in blood-based samples from a subject with high sensitivity, accuracy, and precision. The assay comprises contacting a sample with a capture antibody directed against a p217+tau epitope to bind the capture antibody to p217+tau peptides in plasma to form antibody-peptide complexes, and separately contacting the antibody-peptide complexes with a detection antibody to bind the detection antibody to the antibody-peptide complexes. The amount of p217+tau is determined by detecting the detection antibody. The amount of p217+tau detected is used to determine whether the subject has tauopathy or is at risk of developing tauopathy, or whether the subject has amyloidogenic disease or is at risk of developing amyloidogenic disease when the amount of p217+tau peptides is above a predetermined threshold value. The method has improved sensitivity such that the predetermined threshold value is above a Lower Limit of Quantification and/or Lower Limit of Detection of the assay.

Abstract: Disclosed is a device for accommodating a cable assembly. The device comprises a casing having a receiving portion with a connecting piece which is connected at its first end to the casing and extends away from the casing toward its second end; with two side sections each connected to the connecting piece at one end, extending toward the other end away from the connecting piece, and extending in different directions. The device further comprises a cover having an insertion part for insertion into the receiving portion, the insertion part having two sub-sections and each sub-section has an engaging element. The device is designed such that the insertion part can be inserted into the receiving portion, wherein the connecting piece is then located between the sub-sections. When the insertion part is inserted until each engaging element has passed a side section, the engaging elements prevent the insertion part from sliding out.

Abstract: Methods of measuring the amount of singly- or multiply-phosphorylated p217+ tau protein in a sample are provided. Methods of detecting or diagnosing tauopathies, methods of determining the effectiveness of a treatment of a tauopathy, and methods of determining whether a subject is suitable for anti-p217+ tau antibody therapy are also provided. Also described are antibodies for use in the methods and kits comprising the antibodies.

Abstract: Methods of measuring the amount of singly- or multiply-phosphorylated p217+ tau protein in a sample are provided. Methods of detecting or diagnosing tauopathies, methods of determining the effectiveness of a treatment of a tauopathy, and methods of determining whether a subject is suitable for anti-p217+ tau antibody therapy are also provided. Also described are antibodies for use in the methods and kits comprising the antibodies.

Abstract: Methods of measuring the amount of singly- or multiply-phosphorylated p217+ tau protein in a sample are provided. Methods of detecting or diagnosing tauopathies, methods of determining the effectiveness of a treatment of a tauopathy, and methods of determining whether a subject is suitable for anti-p217+ tau antibody therapy are also provided. Also described are antibodies for use in the methods and kits comprising the antibodies.

Abstract: A clip with a head and a shank extending along a longitudinal axis from the head in which ribs are provided, each rib extending from a base of the respective rib on the shank to an end of the respective rib radially spaced from the base of the respective rib, a rib is connected in sections directly to the head, a rib has an elastic arm which protrudes from the respective rib, a rib has a side extending between the rib base and the rib end, wherein the elastic arm of this rib protrudes from this side of the rib, an elastic arm having first and second sections, the first section being connected at one end to the rib and at its other end to the second section, the second section extending in a different direction from the first section, the first section is connected directly to the head.

Abstract: An elevator car for transporting people and goods and having a floor panel, at least three side panels, and a roof panel together forming a door opening. The floor panel, at least one side panel, and the roof panel are unitarily formed of a thermoplastic synthetic resin. A force-spreading element substantially more rigid than the panels is fixed in or on an face of one of the side panels or the roof panel. A hoist system for the car is fixed by fasteners to the load-spreading element.

Abstract: Methods of measuring the amount of singly- or multiply-phosphorylated p217+ tau protein in a sample are provided. Methods of detecting or diagnosing tauopathies, methods of determining the effectiveness of a treatment of a tauopathy, and methods of determining whether a subject is suitable for anti-p217+ tau antibody therapy are also provided. Also described are antibodies for use in the methods and kits comprising the antibodies.

Abstract: Methods of measuring the amount of singly- or multiply-phosphorylated p217+ tau protein in a sample are provided. Methods of detecting or diagnosing tauopathies, methods of determining the effectiveness of a treatment of a tauopathy, and methods of determining whether a subject is suitable for anti-p217+ tau antibody therapy are also provided. Also described are antibodies for use in the methods and kits comprising the antibodies.

Abstract: A plug-in nut has an outer body and an inner body which is mounted in the outer body such that it can be displaced in a rotationally fixed manner. On the inner body, rear-latching lugs are formed on spring arms, which rear-latching lugs fix an attachment component on a carrier part in a variable position of the inner body in relation to the outer body, which variable position is assumed so as to compensate for tolerances, as soon as a screw has been screwed into a screw receiving space of the inner body. This results in a secure hold with very simple handling.

Abstract: A plug-in nut has an outer body and an inner body which is mounted in the outer body such that it can be displaced in a rotationally fixed manner. On the inner body, rear-latching lugs are formed on spring arms, which rear-latching lugs fix an attachment component on a carrier part in a variable position of the inner body in relation to the outer body, which variable position is assumed so as to compensate for tolerances, as soon as a screw has been screwed into a screw receiving space of the inner body. This results in a secure hold with very simple handling.

Abstract: An actuating mechanism for a manual selector-push electrical multiswitch, for example, having an actuating member including a plurality of actuating portions which can be rotatably positioned with respect to the switches to select a predetermined control pattern and reciprocally moved to actuate and deactuate the switches to bring the control pattern about, where the actuating portions can be selectively removed to provide further patterns.