Patents by Inventor Christian L. A. Renault

Christian L. A. Renault has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Patent number: 4711890
    Abstract: Compounds of the formula: ##STR1## in which R.sub.1 is C.sub.1-6 alkyl, phenyl, C.sub.3-6 cycloalkyl, phenylalkyl, cycloalkyl-alkyl or ##STR2## R.sub.3 and R.sub.4 being H or alkyl, R.sub.5 being alkenyl or alkynyl, and the sum of the carbon atoms in R.sub.3, R.sub.4 and R.sub.5 being 2 to 5, R.sub.2 is as defined for R.sub.1 and may also represent ##STR3## in which n is 0, 1, 2 or 3, it also being possible for R.sub.1 and R.sub.2 to form, with the nitrogen atom to which they are attached, a 5-, 6- or 7-membered heterocyclic radical which can contain another hetero-atom chosen from O and N and which can carry 1 or 2 substituents, Z is phenyl, pyridinyl, thienyl, thiazol-2-yl or substituted phenyl, X and R.sub.0 are H, halogen, C.sub.1-3 alkyl, C.sub.1-3 alkoxy, nitro or CF.sub.3, A represents N or CH and E represents N or CH, some of which are known compounds, are therapeutically useful compounds useful in the treatment of anxiety states or of pulmonary, renal, circulatory or cardiovascular disorders.
    Type: Grant
    Filed: December 22, 1983
    Date of Patent: December 8, 1987
    Assignee: Rhone-Poulenc Sante
    Inventors: Marie-Christine Dubroeucq, Gerard R. Le Fur, Christian L. A. Renault
  • Patent number: 4684652
    Abstract: Compounds of the formula: ##STR1## in which R.sub.1 is C.sub.1-6 alkyl, phenyl, C.sub.3-6 cycloalkyl, phenylalkyl, cycloalkyl-alkyl or ##STR2## R.sub.3 and R.sub.4 being H or alkyl, R.sub.5 being alkenyl or alkynyl, and the sum of the carbon atoms in R.sub.3, R.sub.4 and R.sub.5 being 2 to 5, R.sub.2 is as defined for R.sub.1 and may also represent ##STR3## in which n is 0, 1, 2 or 3, it also being possible for R.sub.1 and R.sub.2 to form, with the nitrogen atom to which they are attached, a 5-, 6- or 7-membered heterocyclic radical which can contain another hetero-atom chosen from O and N and which can carry 1 or 2 substituents, Z is phenyl, pyridinyl, thienyl, thiazol-2-yl or substituted phenyl, X and R.sub.0 are H, halogen, C.sub.1-3 alkyl, C.sub.1-3 alkoxy, nitro or CF.sub.3, A represents N or CH and E represents N or CH, some of which are known compounds, are therapeutically useful compounds useful in the treatment of anxiety states or of pulmonary, renal, circulatory or cardiovascular disorders.
    Type: Grant
    Filed: August 8, 1985
    Date of Patent: August 4, 1987
    Assignee: Rhone-Poulenc Sante
    Inventors: Marie-Christine Dubroeucq, Gerard R. Le Fur, Christian L. A. Renault
  • Patent number: 4613607
    Abstract: Antiarhythmic medicaments containing, as active substance, a compound of the formula: ##STR1## in which n is 1 or 2, X and Y are fixed in positions 5, 6, 7 or 8 on the quinoline cycle and each represents a hydrogen atom or an alkoxy group having 1 to 3 carbons, R is a hydrogen atom or an alkyl group having 1 to 4 carbons, cycloalkyl having 3 to 8 carbons, phenyl or phenyl substituted by alkoxy having 1 to 4 carbons, R.sub.1 is a hydrogen atom or an alkyl group having 1 to 4 carbons or a phenylalkyl group of which the alkyl part has 1 to 3 carbons, R.sub.2 is a hydrogen atom, an alkyl group having 1 to 2 carbons or an alkenyl group having 2 to 4 carbons.
    Type: Grant
    Filed: September 30, 1983
    Date of Patent: September 23, 1986
    Assignee: Pharmuka Laboratoires
    Inventors: Claude G. A. Gueremy, Michel A. P. Mestre, Christian L. A. Renault
  • Patent number: 4505916
    Abstract: Compounds, useful as medicaments, of the formula: ##STR1## in which R is hydrogen, alkyl, alkenyl or arylalkyl, R.sub.1 is hydrogen, alkyl or alkenyl, R.sub.2 is hydrogen, alkyl, arylalkyl, phenyl, pyridyl, thienyl or substituted phenyl, X is hydrogen, halogen, alkyl, alkoxy, alkylthio, trifluoromethyl, nitro, amino or amino substituted by one or two alkyl groups, and A represents a CO or CH.sub.2 group.
    Type: Grant
    Filed: September 29, 1982
    Date of Patent: March 19, 1985
    Assignee: Pharmindustrie
    Inventors: Alain A. Champseix, Gerard R. Le Fur, Christian L. A. Renault
  • Patent number: 4435410
    Abstract: Compounds of the general formula: ##STR1## in which X represents a hydrogen or halogen atom, for example fluorine or chlorine, and R represents an alkyl group having 1 to 3 carbon atoms or alkenyl group having 2 to 3 carbon atoms are disclosed together with methods for their preparation and their use in the treatment of migraines, as anti-thrombosis agents or as rapid acting thymoanaleptic medicaments.
    Type: Grant
    Filed: May 3, 1982
    Date of Patent: March 6, 1984
    Assignee: Pharmindustrie
    Inventors: Gerard R. Le Fur, Christian L. A. Renault
  • Patent number: 4433150
    Abstract: Compounds, useful as medicaments, of the formula: ##STR1## in which R is hydrogen, alkyl, alkenyl or arylalkyl, R.sub.1 is hydrogen, alkyl or alkenyl, R.sub.2 is hydrogen, alkyl, arylalkyl, phenyl, pyridyl, thienyl or substituted phenyl, X is hydrogen, halogen, alkyl, alkoxy, alkylthio, trifluoromethyl, nitro, amino or amino substituted by one or two alkyl groups, and A represents a CO or CH.sub.2 group.
    Type: Grant
    Filed: December 2, 1980
    Date of Patent: February 21, 1984
    Assignee: Pharmindustrie
    Inventors: Alain A. Champseix, Gerard R. Le Fur, Christian L. A. Renault
  • Patent number: 4357337
    Abstract: Compounds, which can be used as medicaments, of the formula: ##STR1## in which n is 1, 2 ore 3, X is fixed in position 4, 5, 6 or 7 on the cycle ##STR2## and represents a hydrogen atom or a halogen atom or an alkyl, alkoxy or alkylthio group having 1 to 4 carbon atoms, the ##STR3## is fixed in position 2 or 3 on the cycle ##STR4## and the broken line represents a second possible bond, are disclosed for the treatment of states of depression, as analgesics and anti-migraine substances.
    Type: Grant
    Filed: June 8, 1981
    Date of Patent: November 2, 1982
    Assignee: Pharmindustrie
    Inventors: Marie-Christine Dubroeucq, Claude G. A. Gueremy, Christian L. A. Renault, Gerard R. Le Fur
  • Patent number: 4224332
    Abstract: The compounds of the formula: ##STR1## in which Ar is phenyl or phenyl substituted by 1 or 2 alkoxy groups, by a halogen atom or by a trifluoromethyl group are disclosed together with a process for the preparation thereof. These compounds are antidepressants and antiparkinson agents.
    Type: Grant
    Filed: December 28, 1978
    Date of Patent: September 23, 1980
    Assignee: Pharmindustrie
    Inventors: Claude G. A. Gueremy, Francoise Hodac, Christian L. A. Renault