Patents by Inventor Christian Larroque

Christian Larroque has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Patent number: 9409988
    Abstract: The present invention relates to anti-Axl antibodies and uses thereof in diagnostic and therapeutic methods. More particularly, the present invention relates to a monoclonal antibody having specificity for Axl comprising an heavy chain variable region comprising SEQ ID NO:2 in the H-CDR1 region, SEQ ID NO:3 in the H-CDR2 region and SEQ ID NO:4 in the H-CDR3 region; and a light chain variable region comprising SEQ ID NO: 6 in the L-CDR1 region, SEQ ID NO:7 in the L-CDR2 region and SEQ ID NO:8 in the L-CDR3 region. Said monoclonal antibody binds to the extracellular domain of Axl via, SEQ ID NO:9 and SEQ ID NO: 10.
    Type: Grant
    Filed: June 22, 2012
    Date of Patent: August 9, 2016
    Assignees: INSERM (Institut National De La Sante Et De La Recherche Medicale), ORIBASE Pharma, UNIVERSITE De Montpellier 1, INSTITUT Regional Du Cancer De Montpellier-Val D'Aurelle
    Inventors: Bruno Robert, Benedicte Fauvel, Gwenael Cheve, Aziz Yasri, Christel Larbouret, Wilhem Leconet, Thierry Chardes, Christian Larroque, Andre Pelegrin
  • Patent number: 9249228
    Abstract: The present invention relates to anti-Axl antibodies and uses thereof in diagnostic and therapeutic methods. More particularly, the present invention relates to a monoclonal antibody having specificity for Axl comprising an heavy chain variable region comprising SEQ ID NO:2 in the H-CDR1 region, SEQ ID NO:3 in the H-CDR2 region and SEQ ID NO:4 in the H-CDR3 region; and a light chain variable region comprising SEQ ID NO: 6 in the L-CDR1 region, SEQ ID NO:7 in the L-CDR2 region and SEQ ID NO:8 in the L-CDR3 region. Said monoclonal antibody binds to the extracellular domain of Axl via, SEQ ID NO:9, SEQ ID NO: 10 and SEQ ID NO: 11.
    Type: Grant
    Filed: June 22, 2012
    Date of Patent: February 2, 2016
    Assignees: ORIBASE PHARMA, Institut Regional du Cancer de Montpellier-Val d' Aurelle, INSERM (Institut National de la Sante et de la Recherche Medicale), UNIVERSITE DE MONTPELLIER 1
    Inventors: Bruno Robert, Benedicte Fauvel, Gwenael Cheve, Aziz Yasri, Christel Larbouret, Wilhem Leconet, Thierry Chardes, Christian Larroque, Andre Pelegrin
  • Patent number: 9102716
    Abstract: The present invention relates to the use of a peptide consisting of 5 to 30 amino acid residues comprising an amino acid sequence selected from LLADTTHHRPWT (SEQ ID NO: 1), SPGLSLVSHMQT (SEQ ID NO: 2), and the sequences presenting at least 80% identity with SEQ ID NO: 1 or SEQ ID NO: 2, for the functionalization of silicon substrate. The present invention also relates to the specific peptides as such, and to silicon substrates functionalized by the adsorption on their surface of such specific peptides. Finally, the present invention is also directed to a process for the preparation of such functionalized silicon substrates, and to articles comprising a silicon substrate according to the invention.
    Type: Grant
    Filed: May 5, 2011
    Date of Patent: August 11, 2015
    Assignees: Centre National de la Recherche Scientifique, Universite Montpellier I
    Inventors: Csilla Gergely, Elias Estephan, Marie-belle Saab, Christian Larroque, Frédéric Cuisinier
  • Publication number: 20140302041
    Abstract: The present invention relates to anti-Axl antibodies and uses thereof in diagnostic and therapeutic methods. More particularly, the present invention relates to a monoclonal antibody having specificity for Axl comprising an heavy chain variable region comprising SEQ ID NO:2 in the H-CDR1 region, SEQ ID NO:3 in the H-CDR2 region and SEQ ID NO:4 in the H-CDR3 region; and a light chain variable region comprising SEQ ID NO: 6 in the L-CDR1 region, SEQ ID NO:7 in the L-CDR2 region and SEQ ID NO:8 in the L-CDR3 region. Said monoclonal antibody binds to the extracellular domain of Axl via, SEQ ID NO:9, SEQ ID NO: 10 and SEQ ID NO: 11.
    Type: Application
    Filed: June 22, 2012
    Publication date: October 9, 2014
    Applicants: ORIBASE PHARMA, Institut Regional du Cancer de Montpellier-Val d' Aurelle, INSERM (Institut National de la Sante et de la Recherche Medicale), UNIVERSITE DE MONTPELLIER 1
    Inventors: Bruno Robert, Benedicte Fauvel, Gwenael Cheve, Aziz Yasri, Christel Larbouret, Wilhem Leconet, Thierry Chardes, Christian Larroque, Andre Pelegrin
  • Publication number: 20140227283
    Abstract: The present invention relates to anti-Axl antibodies and uses thereof in diagnostic and therapeutic methods. More particularly, the present invention relates to a monoclonal antibody having specificity for Axl comprising an heavy chain variable region comprising SEQ ID NO:2 in the H-CDR1 region, SEQ ID NO:3 in the H-CDR2 region and SEQ ID NO:4 in the H-CDR3 region; and a light chain variable region comprising SEQ ID NO: 6 in the L-CDR1 region, SEQ ID NO:7 in the L-CDR2 region and SEQ ID NO:8 in the L-CDR3 region. Said monoclonal antibody binds to the extracellular domain of Axl via, SEQ ID NO:9 and SEQ ID NO: 10.
    Type: Application
    Filed: June 22, 2012
    Publication date: August 14, 2014
    Applicants: INSERM (Institut National de la Sante et de la Recherche Medicale), Institut Regional du Cancer de Montpellier-Val d'Aurelle, UNIVERSITE DE MONTPELLIER 1, OriBase Pharma
    Inventors: Bruno Robert, Benedicte Fauvel, Gwenael Cheve, Aziz Yasri, Christel Larbouret, Wilhem Leconet, Thierry Chardes, Christian Larroque, Andre Pelegrin
  • Patent number: 8449961
    Abstract: The present invention relates to a pipe usable for an air intake circuit of a motor vehicle engine, and to this air intake circuit in particular for the intake of air at the outlet of a turbocompressor that comprises at least one such pipe. This pipe (1) comprises at least one inner elastomer layer (10), one outer elastomer layer (16), one intermediate elastomer layer (12) and one reinforcing structure (14) which is situated between the intermediate and outer layers and which comprises yarns based on an aliphatic polyester, such as a PET, each intermediate and outer layer being formed from a composition based on at least one acrylate copolymer (ACM). According to the invention, said composition is crosslinked by means of a system chosen from the group consisting of those based on at least one soap combined with sulfur, with a urea derivative and those based on a thiadiazole.
    Type: Grant
    Filed: June 13, 2011
    Date of Patent: May 28, 2013
    Assignee: Hutchinson
    Inventors: Ludovic Nicolas, Gwenaëlle Bierce-Argy, Sandrine Houee, Christian Larroque, Alper Caliskan
  • Publication number: 20130131314
    Abstract: The present invention relates to the use of a peptide consisting of 5 to 30 amino acid residues comprising an amino acid sequence selected from LLADTTHHRPWT (SEQ ID NO: 1), SPGLSLVSHMQT (SEQ ID NO: 2), and the sequences presenting at least 80% identity with SEQ ID NO: 1 or SEQ ID NO: 2, for the funcfionalization of silicon substrate. The present invention also relates to the specific peptides as such, and to silicon substrates functionalized by the adsorption on their surface of such specific peptides. Finally, the present invention is also directed to a process for the preparation of such functionalized silicon substrates, and to articles comprising a silicon substrate according to the invention.
    Type: Application
    Filed: May 5, 2011
    Publication date: May 23, 2013
    Applicants: UNIVERSITE MONTPELLIER I, CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE
    Inventors: Csilla Gergely, Elias Estephan, Marie-Belle Saab, Christian Larroque, Frédéric Cuisinier
  • Publication number: 20110303318
    Abstract: The present invention relates to a pipe usable for an air intake circuit of a motor vehicle engine, and to this air intake circuit in particular for the intake of air at the outlet of a turbocompressor that comprises at least one such pipe. This pipe (1) comprises at least one inner elastomer layer (10), one outer elastomer layer (16), one intermediate elastomer layer (12) and one reinforcing structure (14) which is situated between the intermediate and outer layers and which comprises yarns based on an aliphatic polyester, such as a PET, each intermediate and outer layer being formed from a composition based on at least one acrylate copolymer (ACM). According to the invention, said composition is crosslinked by means of a system chosen from the group consisting of those based on at least one soap combined with sulfur, with a urea derivative and those based on a thiadiazole.
    Type: Application
    Filed: June 13, 2011
    Publication date: December 15, 2011
    Inventors: Ludovic Nicolas, Gwenaëlle Bierce-Argy, Sandrine Houee, Christian Larroque, Alper Caliskan