Patents by Inventor Christian Loesche

Christian Loesche has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • LTA4H INHIBITORS FOR THE TREATMENT OF HIDRADENITIS SUPPURATIVA
    Publication number: 20220117949
    Abstract: The present disclosure relates to methods for treating Hidradenitis Suppurativa using a LTA4H inhibitor. Also disclosed herein are LTA4H inhibitors, for treating Hidradenitis Suppurativa patients, as well as medicaments, dosing regimens, pharmaceutical formulations, combinations, dosage forms, and kits for use in the disclosed uses and methods.
    Type: Application
    Filed: January 9, 2020
    Publication date: April 21, 2022
    Inventors: Christian Loesche, Carlos PENNO, Till Roehn, Grazyna Wieczorek
  • ANTI-CD40 ANTIBODIES FOR USE IN TREATMENT OF HIDRADENITIS
    Publication number: 20220098315
    Abstract: The disclosure relates to methods, treatment regimens, uses, kits and therapies for treating hidradenitis suppurativa, by employing CD40 antagonists, such as anti-CD40 antibodies.
    Type: Application
    Filed: January 9, 2020
    Publication date: March 31, 2022
    Inventors: Pascal ESPIE, Christian LOESCHE, Lukas ROTH, James RUSH, Grazyna WIECZOREK
  • METHOD OF TREATING HIDRADENTITIS SUPPURATIVA WITH IL-17 ANTAGONISTS
    Publication number: 20200277369
    Abstract: The present disclosure relates to methods for treating Hidradenitis Suppurativa (HS) using IL-17 antagonists, e. g., secukinumab. Also disclosed herein are IL-17 antagonists, e.g., IL-17 antibodies, such as secukinumab, for treating HS patients, as well as medicaments, dosing regimens, pharmaceutical formulations, dosage forms, and kits for use in the disclosed uses and methods.
    Type: Application
    Filed: November 11, 2018
    Publication date: September 3, 2020
    Applicant: Novartis AG
    Inventors: Christian Loesche, Anna Maria DE VERA JUAREZ, Gerard BRUIN, Farkad Ezzet
  • Methods and compositions for safe and effective treatment of erythema
    Patent number: 9861632
    Abstract: Improved methods and compositions for safe and effective treatment of erythema or a symptom associated with erythema in a subject are described. The methods involve topically applying to an affected skin area a topical composition comprising about 0.3% to about 10% by weight of brimonidine and a pharmaceutically acceptable carrier.
    Type: Grant
    Filed: December 14, 2015
    Date of Patent: January 9, 2018
    Assignee: Galderma Laboratories, L.P.
    Inventors: Michael Graeber, Christian Loesche, Philip Freidenreich, Yin-sang Liu, Matthew James Leoni
  • Methods and compositions for safe and effective treatment of erythema
    Patent number: 9861631
    Abstract: Improved methods and compositions for safe and effective treatment of erythema or a symptom associated with erythema in a subject are described. The methods involve topically applying to an affected skin area a topical composition comprising about 0.3% to about 10% by weight of brimonidine and a pharmaceutically acceptable carrier.
    Type: Grant
    Filed: April 6, 2015
    Date of Patent: January 9, 2018
    Assignee: Galderma Laboratories, L.P.
    Inventors: Michael Graeber, Christian Loesche, Philip Freidenreich, Yin-sang Liu, Matthew James Leoni
  • METHODS AND COMPOSITIONS FOR TREATING OR PREVENTING ERYTHEMA
    Publication number: 20170296535
    Abstract: Methods and products for treating or preventing erythema or a symptom associated with erythema in a subject are described. The methods involve topically applying to an affected skin area a topical aqueous gel composition comprising about 0.01% to about 10% by weight of at least one ?-adrenergic receptor agonist and a pharmaceutically acceptable carrier.
    Type: Application
    Filed: June 28, 2017
    Publication date: October 19, 2017
    Inventors: Michael GRAEBER, Christian LOESCHE, Philip FREIDENREICH, Jack A. DEJOVIN, Isabelle Jean DEJOVIN, Yin-sang LIU, Matthew James LEONI
  • COMBINATION/ASSOCIATION OF ADAPALENE AND BENZOYL PEROXIDE FOR TREATING ACNE
    Publication number: 20170202803
    Abstract: Acne lesions, whether of inflammatory and/or non-inflammatory type, are simultaneously or sequentially treated and their number reduced, via daily topical regimen, with the combination or association of adapalene or pharmaceutically acceptable salt thereof and benzoyl peroxide (BPO).
    Type: Application
    Filed: March 31, 2017
    Publication date: July 20, 2017
    Inventors: Marie-Line Abou Chacra VERNET, Denis GROSS, Christian LOESCHE, Michel PONCET
  • METHODS AND COMPOSITIONS FOR TREATING OR PREVENTING ERYTHEMA
    Publication number: 20170087085
    Abstract: Methods and products for treating or preventing erythema or a symptom associated with erythema in a subject are described. The methods involve topically applying to an affected skin area a topical aqueous gel composition comprising about 0.01% to about 10% by weight of at least one ?-adrenergic receptor agonist and a pharmaceutically acceptable carrier.
    Type: Application
    Filed: December 8, 2016
    Publication date: March 30, 2017
    Inventors: Michael GRAEBER, Christian LOESCHE, Philip FREIDENREICH, Jack A. DEJOVIN, Isabelle Jean DEJOVIN, Yin-sang LIU, Matthew James LEONI
  • METHODS AND COMPOSITIONS FOR SAFE AND EFFECTIVE TREATMENT OF ERYTHEMA
    Publication number: 20160095857
    Abstract: Improved methods and compositions for safe and effective treatment of erythema or a symptom associated with erythema in a subject are described. The methods involve topically applying to an affected skin area a topical composition comprising about 0.3% to about 10% by weight of brimonidine and a pharmaceutically acceptable carrier.
    Type: Application
    Filed: December 14, 2015
    Publication date: April 7, 2016
    Inventors: Michael GRAEBER, Christian LOESCHE, Philip FREIDENREICH, Yin-sang LIU, Matthew James LEONI
  • METHODS AND COMPOSITIONS FOR TREATING OR PREVENTING ERYTHEMA
    Publication number: 20160008355
    Abstract: Methods and products for treating or preventing erythema or a symptom associated with erythema in a subject are described. The methods involve topically applying to an affected skin area a topical aqueous gel composition comprising about 0.01% to about 10% by weight of at least one ?-adrenergic receptor agonist and a pharmaceutically acceptable carrier.
    Type: Application
    Filed: September 23, 2015
    Publication date: January 14, 2016
    Inventors: Michael GRAEBER, Christian LOESCHE, Philip FREIDENREICH, Jack A. DEJOVIN, Isabelle Jean DEJOVIN, Yin-sang LIU, Matthew James LEONI
  • METHODS AND COMPOSITIONS FOR SAFE AND EFFECTIVE TREATMENT OF ERYTHEMA
    Publication number: 20150209350
    Abstract: Improved methods and compositions for safe and effective treatment of erythema or a symptom associated with erythema in a subject are described. The methods involve topically applying to an affected skin area a topical composition comprising about 0.3% to about 10% by weight of brimonidine and a pharmaceutically acceptable carrier.
    Type: Application
    Filed: April 6, 2015
    Publication date: July 30, 2015
    Inventors: Michael GRAEBER, Christian LOESCHE, Philip FREIDENREICH, Yin-sang LIU, Matthew James LEONI
  • Methods and compositions for safe and effective treatment of telangiectasia
    Patent number: 8916562
    Abstract: Improved methods and compositions for safe and effective treatment of telangiectasia or a symptom associated with telangiectasia in a subject are described. The methods involve topically applying to an affected skin area a topical composition comprising about 0.3% to about 10% by weight of brimonidine and a pharmaceutically acceptable carrier.
    Type: Grant
    Filed: March 25, 2011
    Date of Patent: December 23, 2014
    Assignee: Galderma Research & Development SNC
    Inventors: Michael Graeber, Christian Loesche, Philip Freidenreich, Yin Liu, Matthew James Leoni
  • COMBINATION/ASSOCIATION OF ADAPALENE AND BENXOYL PEROXIDE FOR TREATING ACNE LESIONS
    Publication number: 20140296340
    Abstract: Acne lesions, whether of inflammatory and/or non-inflammatory type, are simultaneously or sequentially treated and their number reduced, via daily topical regimen, with the combination or association of adapalene or pharmaceutically acceptable salt thereof and benzoyl peroxide (BPO).
    Type: Application
    Filed: June 11, 2014
    Publication date: October 2, 2014
    Inventors: Marie-Line Abou Chacra VERNET, Denis GROSS, Christian LOESCHE, Michel PONCET
  • Combination/association of adapalene and benzoyl peroxide for treating acne lesions
    Patent number: 8785420
    Abstract: Acne lesions, whether of inflammatory and/or non-inflammatory type, are simultaneously or sequentially treated and their number reduced, via daily topical regimen, with the combination or association of adapalene or pharmaceutically acceptable salt thereof and benzoyl peroxide (BPO).
    Type: Grant
    Filed: January 17, 2012
    Date of Patent: July 22, 2014
    Assignee: Galderma Research & Development
    Inventors: Marie-Line Abou Chacra Vernet, Denis Gross, Christian Loesche, Michel Poncet
  • METHODS AND COMPOSITIONS FOR SAFE AND EFFECTIVE TREATMENT OF ERYTHEMA
    Publication number: 20140094469
    Abstract: Improved methods and compositions for safe and effective treatment of erythema or a symptom associated with erythema in a subject are described. The methods involve topically applying to an affected skin area a topical composition comprising about 0.3% to about 10% by weight of brimonidine and a pharmaceutically acceptable carrier.
    Type: Application
    Filed: December 5, 2013
    Publication date: April 3, 2014
    Applicant: GALDERMA RESEARCH & DEVELOPMENT
    Inventors: Michael GRAEBER, Christian LOESCHE, Philip FREIDENREICH, Yin-sang LIU, Matthew James LEONI
  • METHODS AND COMPOSITIONS FOR TREATING OR PREVENTING ERYTHEMA
    Publication number: 20140080836
    Abstract: Methods and products for treating or preventing erythema or a symptom associated with erythema in a subject are described. The methods involve topically applying to an affected skin area a topical aqueous gel composition comprising about 0.01% to about 10% by weight of at least one ?-adrenergic receptor agonist and a pharmaceutically acceptable carrier.
    Type: Application
    Filed: November 19, 2013
    Publication date: March 20, 2014
    Applicant: GALDERMA LABORATORIES INC.
    Inventors: Michael GRAEBER, Christian LOESCHE, Philip FREIDENREICH, Jack A. DEJOVIN, Isabelle Jean DEJOVIN, Yin-sang LIU, Matthew James LEONI
  • COMBINATIONS OF ADAPALENE AND BENZOYL PEROXIDE FOR TREATING ACNE LESIONS
    Publication number: 20140031427
    Abstract: Adapalene or a pharmaceutically acceptable salt thereof formulated into a pharmaceutical composition is useful for reducing the number of acne lesions, via daily topical application, in combination or in association with benzoyl peroxide (BPO); such treatment may be via administration of a pharmaceutical composition combining adapalene and BPO or by a concomitant application of two pharmaceutical compositions, one containing adapalene and the other containing BPO.
    Type: Application
    Filed: September 26, 2013
    Publication date: January 30, 2014
    Applicant: GALDERMA RESEARCH & DEVELOPMENT
    Inventors: Marie-Line ABOU-CHACRA VERNET, Denis GROSS, Christian LOESCHE, Michel PONCET
  • Methods and compositions for treating or preventing erythema
    Patent number: 8586586
    Abstract: Methods and products for treating or preventing erythema or a symptom associated with erythema in a subject are described. The methods involve topically applying to an affected skin area a topical aqueous gel composition comprising about 0.01% to about 10% by weight of at least one ?-adrenergic receptor agonist and a pharmaceutically acceptable carrier.
    Type: Grant
    Filed: March 8, 2013
    Date of Patent: November 19, 2013
    Assignee: Galderma Laboratories Inc.
    Inventors: Michael Graeber, Christian Loesche, Philip Freidenreich, Jack A. DeJovin, Isabelle Jean DeJovin, Yin-sang Liu, Matthew James Leoni
  • Pivot arrangement
    Patent number: 8550740
    Abstract: A joint and/or bearing arrangement (1) with a pivot pin (2), in particular with a pivot pin (2) having a head region (3) which is movable with respect to a receiving joint socket (4), wherein the pivot pin (2) is at least partially surrounded by a circumferential sealing collar (7), is configured so that the outside of the sealing collar (7) is covered by a separate protective cover (11) which conforms to the shape of the sealing collar.
    Type: Grant
    Filed: July 23, 2008
    Date of Patent: October 8, 2013
    Assignee: ZF Friedrichshafen AG
    Inventors: Hans-Gerd Brunneke, Christian Lösche, Werner Schmudde
  • COMBINATIONS OF ADAPALENE AND BENZOYL PEROXIDE FOR TREATING ACNE LESIONS
    Publication number: 20130253062
    Abstract: Adapalene or a pharmaceutically acceptable salt thereof formulated into a pharmaceutical composition is useful for reducing the number of acne lesions, via daily topical application, in combination or in association with benzoyl peroxide (BPO); such treatment may be via administration of a pharmaceutical composition combining adapalene and BPO or by a concomitant application of two pharmaceutical compositions, one containing adapalene and the other containing BPO.
    Type: Application
    Filed: May 13, 2013
    Publication date: September 26, 2013
    Applicant: GALDERMA RESEARCH & DEVELOPMENT
    Inventors: Marie-Line ABOU-CHACRA VERNET, Denis GROSS, Christian LOESCHE, Michel PONCET