Patents by Inventor Christian Lothschütz

Christian Lothschütz has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Preparation of racemic nicotine by reaction of ethyl nicotinate with N-vinylpyrrolidone in the presence of an alcoholate base and subsequent process steps
    Patent number: 11407730
    Abstract: The present invention relates to a method of preparing racemic nicotine comprising: (i) reacting ethyl nicotinate and N-vinylpyrrolidone in the presence of an alcoholate base to 3-nicotinoyl-1-vinylpyrrolidin-2-one; (ii) reacting the 3-nicotinoyl-1-vinylpyrrolidin-2-one with an acid to myosmine; (iii) reducing the myosmine to nornicotine using a reducing agent; and (iv) methylating the nornicotine to obtain the racemic nicotine.
    Type: Grant
    Filed: December 18, 2018
    Date of Patent: August 9, 2022
    Assignees: Siegfried AG, Contraf-Nicotex-Tobacco GmbH
    Inventors: Beat Theodor Weber, Christian Lothschütz, Ben Pan
  • Preparation of racemic nicotine by reaction of ethyl nicotinate with N-vinylpyrrolidone in the presence of an alcoholate base and subsequent process steps
    Patent number: 11091458
    Abstract: The present invention relates to a method of preparing racemic nicotine comprising: (i) reacting ethyl nicotinate and N-vinylpyrrolidone in the presence of an alcoholate base to 3-nicotinoyl-1-vinylpyrrolidin-2-one; (ii) reacting the 3-nicotinoyl-1-vinylpyrrolidin-2-one with an acid to myosmine; (iii) reducing the myosmine to nornicotine using a reducing agent; and (iv) methylating the nornicotine to obtain the racemic nicotine.
    Type: Grant
    Filed: December 18, 2018
    Date of Patent: August 17, 2021
    Assignees: Siegfried AG, Contraf-Nicotex-Tobacco GmbH
    Inventors: Beat Theodor Weber, Christian Lothschütz, Ben Pan
  • PREPARATION OF RACEMIC NICOTINE BY REACTION OF ETHYL NICOTINATE WITH N-VINYLPYRROLIDONE IN THE PRESENCE OF AN ALCOHOLATE BASE AND SUBSEQUENT PROCESS STEPS
    Publication number: 20200331884
    Abstract: The present invention relates to a method of preparing racemic nicotine comprising: (i) reacting ethyl nicotinate and N-vinylpyrrolidone in the presence of an alcoholate base to 3-nicotinoyl-1-vinylpyrrolidin-2-one; (ii) reacting the 3-nicotinoyl-1-vinylpyrrolidin-2-one with an acid to myosmine; (iii) reducing the myosmine to nornicotine using a reducing agent; and (iv) methylating the nornicotine to obtain the racemic nicotine.
    Type: Application
    Filed: December 18, 2018
    Publication date: October 22, 2020
    Applicants: SIEGFRIED AG, CONTRAF-NICOTEX-TOBACCO GMBH
    Inventors: Beat Theodor Weber, Christian Lothschütz, Ben Pan
  • N-Heterocyclic Carbene Complexes, Their Preparation And Use
    Publication number: 20120108819
    Abstract: Described are N-heterocyclic carbene complexes of the formula I, where n is 0 or 1, M is a metal atom containing group, R1 is selected from hydrogen alkyl, cycloalkyl, heterocycloalkyl, aryl and hetaryl, R2 is selected from hydrogen, alkyl, cycloalkyl, heterocycloalkyl, aryl and hetaryl, wherein R1 and R2 do not both stand for hydrogen. Furthermore, also described are methods for their preparation and their use as catalysts employed in a C—C, C—O, C—N or C—H bond formation reaction.
    Type: Application
    Filed: October 28, 2011
    Publication date: May 3, 2012
    Applicant: BASF SE
    Inventors: A. Stephen K. Hashmi, Christian Lothschütz